Click here to switch to the map view.

The map label for this gene is sigC [H]

Identifier: 118579103

GI number: 118579103

Start: 702581

End: 703429

Strand: Direct

Name: sigC [H]

Synonym: Ppro_0664

Alternate gene names: 118579103

Gene position: 702581-703429 (Clockwise)

Preceding gene: 118579102

Following gene: 118579104

Centisome position: 17.53

GC content: 55.01

Gene sequence:

>849_bases
ATGGTGGCACGTCTTCCGGTTGTTGCGGATAGCCTTGCGCTCTATCTGGCTGAGATCAGAAAATTCACCCTATTGAGCGA
AGAAGAGGAGCATCGCACAGCGATTGCTTTTTACGAGAAAAAGGATCTTCGGGCAGCCCACACCCTGATTACGTCAAACC
TCCGCTTTGTCGTTAGGGTTGCCTATGAGTACCGGCACTATGGCCTCAAGATGCTCGACCTGATCCAGGAGGGTAATATC
GGCCTGATGATGGCGGTGAAAAAATACAACCCTTTTAAGGGGGTACGCCTGATTTCCTACGCGGTCTGGTGGATACGAGC
CTATATTCAGAACCACGTCATATCGGCATGGAGTCTGCTCAAGATAGGAACCACCCAGGCCCAGCGTAAACTTTTTTTTA
AGTTGCGCGAGGCCAGGAACGCAATCCGCCACCTGAACGGAGGAGAGGACGACCTCCAATCCACGGCCCGCTCCTTAAAT
GTGTCCGACAGCGAAGTCGTGGAGATGGAGCAGCGCTTGCGGGGCGAGTGCTCCCTGGATGCAGAGTTGCCGGGCGGCGA
AGGTGTTACCGGGCTGGACGGCCTGGTTGACGATCGCATGAACCAGGAAGAACTCCTGTCGGAGTGCCAGTTGCAGCGCA
AGCTGCGCACGGACGTTGCGACCGCTGTTTCCGCTCTCAATGAAAAGGAACGTTTTGTCATCGAGCATCGGGTTTCCGCA
GATACGCCGCTGACGCTGCAGGAGATTGCCTCCCGTTTCTCAATCTCGCGCGAACGTGTGCGACAGATAGAAGAAGCAGC
GCTTAAGAAGCTGAAGCTGTCCCTTGTGTCAGCGGTAGCAGCAGTTTAG

Upstream 100 bases:

>100_bases
AATATCCTTGATTTTGTGATGGTTTGTTGCTAGATTTTTGGCAGTCGGACGGCTTGAGTGCTAATGTGCGCCAATCTGTC
GTGAACGAGGAGAATCATGT

Downstream 100 bases:

>100_bases
TCGCTTCTGCGTAGGCCGCCACGGTGACTTGGTCGTGATTTTTTTGTTGAATCGAAAAAAACAAATTGACAACCGCTGGT
TTTTTCTTTATAGACATAAA

Product: RNA polymerase sigma-32 subunit RpoH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MVARLPVVADSLALYLAEIRKFTLLSEEEEHRTAIAFYEKKDLRAAHTLITSNLRFVVRVAYEYRHYGLKMLDLIQEGNI
GLMMAVKKYNPFKGVRLISYAVWWIRAYIQNHVISAWSLLKIGTTQAQRKLFFKLREARNAIRHLNGGEDDLQSTARSLN
VSDSEVVEMEQRLRGECSLDAELPGGEGVTGLDGLVDDRMNQEELLSECQLQRKLRTDVATAVSALNEKERFVIEHRVSA
DTPLTLQEIASRFSISRERVRQIEEAALKKLKLSLVSAVAAV

Sequences:

>Translated_282_residues
MVARLPVVADSLALYLAEIRKFTLLSEEEEHRTAIAFYEKKDLRAAHTLITSNLRFVVRVAYEYRHYGLKMLDLIQEGNI
GLMMAVKKYNPFKGVRLISYAVWWIRAYIQNHVISAWSLLKIGTTQAQRKLFFKLREARNAIRHLNGGEDDLQSTARSLN
VSDSEVVEMEQRLRGECSLDAELPGGEGVTGLDGLVDDRMNQEELLSECQLQRKLRTDVATAVSALNEKERFVIEHRVSA
DTPLTLQEIASRFSISRERVRQIEEAALKKLKLSLVSAVAAV
>Mature_282_residues
MVARLPVVADSLALYLAEIRKFTLLSEEEEHRTAIAFYEKKDLRAAHTLITSNLRFVVRVAYEYRHYGLKMLDLIQEGNI
GLMMAVKKYNPFKGVRLISYAVWWIRAYIQNHVISAWSLLKIGTTQAQRKLFFKLREARNAIRHLNGGEDDLQSTARSLN
VSDSEVVEMEQRLRGECSLDAELPGGEGVTGLDGLVDDRMNQEELLSECQLQRKLRTDVATAVSALNEKERFVIEHRVSA
DTPLTLQEIASRFSISRERVRQIEEAALKKLKLSLVSAVAAV

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is essential for normal fruiting body formation [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789871, Length=270, Percent_Identity=38.1481481481481, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1789098, Length=274, Percent_Identity=31.7518248175182, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789448, Length=241, Percent_Identity=29.8755186721992, Blast_Score=100, Evalue=9e-23,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 32030; Mature: 32030

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00715 SIGMA70_1 ; PS00716 SIGMA70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVARLPVVADSLALYLAEIRKFTLLSEEEEHRTAIAFYEKKDLRAAHTLITSNLRFVVRV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYEYRHYGLKMLDLIQEGNIGLMMAVKKYNPFKGVRLISYAVWWIRAYIQNHVISAWSLL
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIGTTQAQRKLFFKLREARNAIRHLNGGEDDLQSTARSLNVSDSEVVEMEQRLRGECSLD
HHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
AELPGGEGVTGLDGLVDDRMNQEELLSECQLQRKLRTDVATAVSALNEKERFVIEHRVSA
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
DTPLTLQEIASRFSISRERVRQIEEAALKKLKLSLVSAVAAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVARLPVVADSLALYLAEIRKFTLLSEEEEHRTAIAFYEKKDLRAAHTLITSNLRFVVRV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYEYRHYGLKMLDLIQEGNIGLMMAVKKYNPFKGVRLISYAVWWIRAYIQNHVISAWSLL
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIGTTQAQRKLFFKLREARNAIRHLNGGEDDLQSTARSLNVSDSEVVEMEQRLRGECSLD
HHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
AELPGGEGVTGLDGLVDDRMNQEELLSECQLQRKLRTDVATAVSALNEKERFVIEHRVSA
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
DTPLTLQEIASRFSISRERVRQIEEAALKKLKLSLVSAVAAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501037 [H]