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The map label for this gene is glcK [H]

Identifier: 118579088

GI number: 118579088

Start: 687825

End: 688802

Strand: Direct

Name: glcK [H]

Synonym: Ppro_0649

Alternate gene names: 118579088

Gene position: 687825-688802 (Clockwise)

Preceding gene: 118579087

Following gene: 118579089

Centisome position: 17.16

GC content: 64.72

Gene sequence:

>978_bases
ATGACGGAAAGGAACACTCTCGCCATAGCCGTTGATATCGGCGGCACCAATCTCCGCTTCGCCCTCGTGGATGCCGCCGG
TTGCGTTCTCTCCCGCAACCGGACTCTCAGTCGTATCGACCATGGCCGCGACCCCTTCTGCCGTCGCCTCCTGGAGGGAA
TCTCCGGGATGGAGCACGAGGCTTCCGCGAGGGGGGCGTCCGTCGTCGGTATTGGCGTCGGTGTGCCCGGACTCGTTGGC
AGGGATGGAATGATCCATGCCTCGGTCAACATGCGCCCCCTGGACGGTTTTGTCCTGTCCAGATTTCTGGAACAGCAGAC
TTCACTGCCGTCCACATGCGACAATGACGCCAACCTCATCGCCCGGGGAGAGGCAGCCCACGGTGCCGGTCGCGGGCTGC
ACTCCTTCGTGGTGATCACCCTCGGAACGGGGGTGGGGAGCGGGCTTGTTCTCGACGGTCGGATCTGGAACGGTGTCGGC
GGTTTTGCCGCGGAATTCGGCCATGTTACGGTTGAGCCGGAAGGGGCGCCCTGTAGCTGCGGCAACAGGGGCTGTCTGGA
ACAGTATGCCTCAGCCAGCGCGATTGCCCGCATCGCGGGGGAACTCATCAAGGGGGGGCAGGTGGATGATGCCTCCCCGC
TGGACGCGGCCCGGGTCGCCCGACTGGCCCGCCAGGGGTGGGTGGAGGCGCAGACGGCATTCGAGGTGGCTGGCCGCTAT
CTGGGGATTGCCCTGGCCTCGTTGACCACGACCCTCAACCTGGAGGCGGCAATCATCTGCGGCGGCGTGGCGCCCAGTCT
GGAGTTGATGCGCCCCTCCCTGGTCAATGAACTGCGGATGCGCTGTTTTTCCCAAATCCTTGCCGATTTTTCAATCCTGC
GGGGCGAACTGGGTGACGACGCCGGGTTGCTGGGGGCAGCCGCGACAATACGTGCCAGGGCCGCCCATGATGTCCCTGGT
GACTCCTTGGCCACTTGA

Upstream 100 bases:

>100_bases
CCAACTTCATGGCGACCTGTGGAGGGGTGAGGGTCATTCCCGACGGACTGCTGGAATCCTACGACCGACTGTATCAGGCC
CTGGGGAGATGTCCCTGATC

Downstream 100 bases:

>100_bases
AGCCGGGGCCTGTGCGCGGCAAGGGGATGAGGGCCAAATCCAGTAGCAATTCATTGACTTTGTGTGGTTTGTTCTATATT
GATACAGATTGCCTGAACCG

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTERNTLAIAVDIGGTNLRFALVDAAGCVLSRNRTLSRIDHGRDPFCRRLLEGISGMEHEASARGASVVGIGVGVPGLVG
RDGMIHASVNMRPLDGFVLSRFLEQQTSLPSTCDNDANLIARGEAAHGAGRGLHSFVVITLGTGVGSGLVLDGRIWNGVG
GFAAEFGHVTVEPEGAPCSCGNRGCLEQYASASAIARIAGELIKGGQVDDASPLDAARVARLARQGWVEAQTAFEVAGRY
LGIALASLTTTLNLEAAIICGGVAPSLELMRPSLVNELRMRCFSQILADFSILRGELGDDAGLLGAAATIRARAAHDVPG
DSLAT

Sequences:

>Translated_325_residues
MTERNTLAIAVDIGGTNLRFALVDAAGCVLSRNRTLSRIDHGRDPFCRRLLEGISGMEHEASARGASVVGIGVGVPGLVG
RDGMIHASVNMRPLDGFVLSRFLEQQTSLPSTCDNDANLIARGEAAHGAGRGLHSFVVITLGTGVGSGLVLDGRIWNGVG
GFAAEFGHVTVEPEGAPCSCGNRGCLEQYASASAIARIAGELIKGGQVDDASPLDAARVARLARQGWVEAQTAFEVAGRY
LGIALASLTTTLNLEAAIICGGVAPSLELMRPSLVNELRMRCFSQILADFSILRGELGDDAGLLGAAATIRARAAHDVPG
DSLAT
>Mature_324_residues
TERNTLAIAVDIGGTNLRFALVDAAGCVLSRNRTLSRIDHGRDPFCRRLLEGISGMEHEASARGASVVGIGVGVPGLVGR
DGMIHASVNMRPLDGFVLSRFLEQQTSLPSTCDNDANLIARGEAAHGAGRGLHSFVVITLGTGVGSGLVLDGRIWNGVGG
FAAEFGHVTVEPEGAPCSCGNRGCLEQYASASAIARIAGELIKGGQVDDASPLDAARVARLARQGWVEAQTAFEVAGRYL
GIALASLTTTLNLEAAIICGGVAPSLELMRPSLVNELRMRCFSQILADFSILRGELGDDAGLLGAAATIRARAAHDVPGD
SLAT

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=266, Percent_Identity=30.8270676691729, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI298566325, Length=266, Percent_Identity=30.8270676691729, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4885285, Length=266, Percent_Identity=30.8270676691729, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI190014632, Length=266, Percent_Identity=30.8270676691729, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1786891, Length=318, Percent_Identity=27.0440251572327, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787878, Length=266, Percent_Identity=22.9323308270677, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87081733, Length=314, Percent_Identity=25.4777070063694, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787363, Length=315, Percent_Identity=25.7142857142857, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790522, Length=285, Percent_Identity=29.8245614035088, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082230, Length=257, Percent_Identity=30.3501945525292, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082127, Length=166, Percent_Identity=26.5060240963855, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33683; Mature: 33552

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERNTLAIAVDIGGTNLRFALVDAAGCVLSRNRTLSRIDHGRDPFCRRLLEGISGMEHE
CCCCCEEEEEEEECCCCEEEEEEEHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCCH
ASARGASVVGIGVGVPGLVGRDGMIHASVNMRPLDGFVLSRFLEQQTSLPSTCDNDANLI
HHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEE
ARGEAAHGAGRGLHSFVVITLGTGVGSGLVLDGRIWNGVGGFAAEFGHVTVEPEGAPCSC
EECCCCCCCCCCHHEEEEEEEECCCCCCEEECCEEECCCCCHHHHCCEEEECCCCCCCCC
GNRGCLEQYASASAIARIAGELIKGGQVDDASPLDAARVARLARQGWVEAQTAFEVAGRY
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
LGIALASLTTTLNLEAAIICGGVAPSLELMRPSLVNELRMRCFSQILADFSILRGELGDD
HHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGLLGAAATIRARAAHDVPGDSLAT
CCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TERNTLAIAVDIGGTNLRFALVDAAGCVLSRNRTLSRIDHGRDPFCRRLLEGISGMEHE
CCCCEEEEEEEECCCCEEEEEEEHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCCH
ASARGASVVGIGVGVPGLVGRDGMIHASVNMRPLDGFVLSRFLEQQTSLPSTCDNDANLI
HHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEE
ARGEAAHGAGRGLHSFVVITLGTGVGSGLVLDGRIWNGVGGFAAEFGHVTVEPEGAPCSC
EECCCCCCCCCCHHEEEEEEEECCCCCCEEECCEEECCCCCHHHHCCEEEECCCCCCCCC
GNRGCLEQYASASAIARIAGELIKGGQVDDASPLDAARVARLARQGWVEAQTAFEVAGRY
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
LGIALASLTTTLNLEAAIICGGVAPSLELMRPSLVNELRMRCFSQILADFSILRGELGDD
HHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGLLGAAATIRARAAHDVPGDSLAT
CCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]