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The map label for this gene is yfbQ [C]

Identifier: 118579061

GI number: 118579061

Start: 658550

End: 659854

Strand: Direct

Name: yfbQ [C]

Synonym: Ppro_0622

Alternate gene names: 118579061

Gene position: 658550-659854 (Clockwise)

Preceding gene: 118579060

Following gene: 118579064

Centisome position: 16.43

GC content: 60.61

Gene sequence:

>1305_bases
ATGCGAATCGAACTGGTACCACCCGGAGCCGGTGAACTGACCTACGAGATCAGAAACATCGTCAACGTGGCTGACAAGTT
GCAGAAGCGCGGCATCAAGGTCAACTGGGAGAATATCGGTGATCCCATCGCCAAGGGGGAGATCATCCCCGCCTGGATGA
AGGAGATCGTGGTCCGGGCGGTCATGGACGATTCCACCTGGGGCTACTGCCACACCCGCGGTGTGCTGGAAACCCGTGAG
TTCATCTGCGACAGGACCAACAGCCGTGGCGGCGCGCACATCACGCCGGACGACATCATCTTCTTCAACGGTCTGGGTGA
CGCCATCGCCAAGGTCTACGGCTGCCTGCGGGCAGGCGCGCGGGTGCTGATGCCCTCACCCTCCTACACCACCCATACCG
TGGGGGAAATCTATCATGCCCAGTCTGCCCCCTCCCTGTTCCGCCTAAAGCCCGAGGACAGGTGGTATCCCGATATCGAC
GAGATGCGCATGCACGTGCGCTACAACCCCAACATCGCCGCCATACTGATCATCAACCCGGACAATCCCACTGGCATGGT
CTATACCCGGGAGATGCTGGAGCAGATCGTCGAGGTGGCCCGGGAAAACAACCTGTTCATCATCGCCGATGAGGTCTATA
CCAACATCGCCTACAACGGCGAAACAACGGTGCCGATCTGCGACGTGATCGGCGACGTGCCGGCCATCTCCATGCGGGGC
ATCTCCAAGGAACTGCCCTGGCCCGGCTCCCGTTGCGGCTGGATCGAGGTGTACAACAGCGACAAGGACGAACACTTCCG
CAAGTACGTCAACCTGATCCTGAACGGAAAGATGAACGAGGTCTGTTCCACCACCCTGCCCCAGACGGTCTTTCCGGCCA
TCATGCGGCACCCCGAGTACCAGCCCTATCTGGCGGAGCGCATCGCCCGCTACGAGAAGATGAGCAACATCACCTACGAC
TACTTGAGCCAGGTGCCGGCCCTGCAGGTCAATCGCACCAACGGCGCTTTCTACATGGCGGTCGCCTTCAGGGAGGGGCT
GCTCAATCATCGCCAGTCGCTTCCCATTGCCAACGCCGATGTCAGGGAGTATATCCAGGGGCTGGTCAACCAGCCGGGGG
TCTCGCCGGACAAACGCTTCGTCTATCACATGCTGGCGGCAACCGGCATCTGCGTGGTGCCGCTCTCCTCCTTCTCCACG
CCGCTGCAGGGGTTCCGCGTGACCCTGCTGGAAAAGGATGAGGACGAGTGCCGCCGCATCTACCAAACCCTGGCGGAGAA
GATAGGCGAGTACCTGCAGTCATAG

Upstream 100 bases:

>100_bases
CGGTCCGGTTCGGCACGTTCGCTATCATGTGGCGGACGCATCTACTCCCGCTCTCCGTGTCGAGCTGATTCCAAGAAACC
ATCGTGGCGGAGGAAAAAAC

Downstream 100 bases:

>100_bases
CTGCGGGTGCCGCTGCCATCGCCGTGGGTTCGCACACGCAGAAACGGGGAGAGGCCCTTGCCTCTCCCCGTTTCTGTATT
CATCCCCCCTGTCAGGGAAG

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRIELVPPGAGELTYEIRNIVNVADKLQKRGIKVNWENIGDPIAKGEIIPAWMKEIVVRAVMDDSTWGYCHTRGVLETRE
FICDRTNSRGGAHITPDDIIFFNGLGDAIAKVYGCLRAGARVLMPSPSYTTHTVGEIYHAQSAPSLFRLKPEDRWYPDID
EMRMHVRYNPNIAAILIINPDNPTGMVYTREMLEQIVEVARENNLFIIADEVYTNIAYNGETTVPICDVIGDVPAISMRG
ISKELPWPGSRCGWIEVYNSDKDEHFRKYVNLILNGKMNEVCSTTLPQTVFPAIMRHPEYQPYLAERIARYEKMSNITYD
YLSQVPALQVNRTNGAFYMAVAFREGLLNHRQSLPIANADVREYIQGLVNQPGVSPDKRFVYHMLAATGICVVPLSSFST
PLQGFRVTLLEKDEDECRRIYQTLAEKIGEYLQS

Sequences:

>Translated_434_residues
MRIELVPPGAGELTYEIRNIVNVADKLQKRGIKVNWENIGDPIAKGEIIPAWMKEIVVRAVMDDSTWGYCHTRGVLETRE
FICDRTNSRGGAHITPDDIIFFNGLGDAIAKVYGCLRAGARVLMPSPSYTTHTVGEIYHAQSAPSLFRLKPEDRWYPDID
EMRMHVRYNPNIAAILIINPDNPTGMVYTREMLEQIVEVARENNLFIIADEVYTNIAYNGETTVPICDVIGDVPAISMRG
ISKELPWPGSRCGWIEVYNSDKDEHFRKYVNLILNGKMNEVCSTTLPQTVFPAIMRHPEYQPYLAERIARYEKMSNITYD
YLSQVPALQVNRTNGAFYMAVAFREGLLNHRQSLPIANADVREYIQGLVNQPGVSPDKRFVYHMLAATGICVVPLSSFST
PLQGFRVTLLEKDEDECRRIYQTLAEKIGEYLQS
>Mature_434_residues
MRIELVPPGAGELTYEIRNIVNVADKLQKRGIKVNWENIGDPIAKGEIIPAWMKEIVVRAVMDDSTWGYCHTRGVLETRE
FICDRTNSRGGAHITPDDIIFFNGLGDAIAKVYGCLRAGARVLMPSPSYTTHTVGEIYHAQSAPSLFRLKPEDRWYPDID
EMRMHVRYNPNIAAILIINPDNPTGMVYTREMLEQIVEVARENNLFIIADEVYTNIAYNGETTVPICDVIGDVPAISMRG
ISKELPWPGSRCGWIEVYNSDKDEHFRKYVNLILNGKMNEVCSTTLPQTVFPAIMRHPEYQPYLAERIARYEKMSNITYD
YLSQVPALQVNRTNGAFYMAVAFREGLLNHRQSLPIANADVREYIQGLVNQPGVSPDKRFVYHMLAATGICVVPLSSFST
PLQGFRVTLLEKDEDECRRIYQTLAEKIGEYLQS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4885351, Length=372, Percent_Identity=27.4193548387097, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4507369, Length=310, Percent_Identity=24.8387096774194, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI19263340, Length=478, Percent_Identity=24.6861924686192, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI215599424, Length=387, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788627, Length=331, Percent_Identity=30.2114803625378, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788722, Length=259, Percent_Identity=26.6409266409266, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=399, Percent_Identity=28.5714285714286, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71981209, Length=384, Percent_Identity=25.5208333333333, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320317, Length=365, Percent_Identity=25.4794520547945, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323118, Length=374, Percent_Identity=22.9946524064171, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859735, Length=395, Percent_Identity=24.5569620253165, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24641770, Length=384, Percent_Identity=24.21875, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641760, Length=384, Percent_Identity=24.21875, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641768, Length=384, Percent_Identity=24.21875, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641766, Length=384, Percent_Identity=24.21875, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641764, Length=384, Percent_Identity=24.21875, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45551451, Length=384, Percent_Identity=24.21875, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 49233; Mature: 49233

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIELVPPGAGELTYEIRNIVNVADKLQKRGIKVNWENIGDPIAKGEIIPAWMKEIVVRA
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHCCCCCHHHHHHHHHHH
VMDDSTWGYCHTRGVLETREFICDRTNSRGGAHITPDDIIFFNGLGDAIAKVYGCLRAGA
HHCCCCCCEEECCCHHHHHHHHHCCCCCCCCCEECCCCEEEECCHHHHHHHHHHHHHHCC
RVLMPSPSYTTHTVGEIYHAQSAPSLFRLKPEDRWYPDIDEMRMHVRYNPNIAAILIINP
EEEECCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHHCEEEEEECCCEEEEEEECC
DNPTGMVYTREMLEQIVEVARENNLFIIADEVYTNIAYNGETTVPICDVIGDVPAISMRG
CCCCCEEEHHHHHHHHHHHHHCCCEEEEEHHHHHEEEECCCCCCHHHHHHCCCCCEECCC
ISKELPWPGSRCGWIEVYNSDKDEHFRKYVNLILNGKMNEVCSTTLPQTVFPAIMRHPEY
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHCCCCC
QPYLAERIARYEKMSNITYDYLSQVPALQVNRTNGAFYMAVAFREGLLNHRQSLPIANAD
CHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHHHHCCCCCCHH
VREYIQGLVNQPGVSPDKRFVYHMLAATGICVVPLSSFSTPLQGFRVTLLEKDEDECRRI
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEEECCHHHHHHH
YQTLAEKIGEYLQS
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRIELVPPGAGELTYEIRNIVNVADKLQKRGIKVNWENIGDPIAKGEIIPAWMKEIVVRA
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHCCCCCHHHHHHHHHHH
VMDDSTWGYCHTRGVLETREFICDRTNSRGGAHITPDDIIFFNGLGDAIAKVYGCLRAGA
HHCCCCCCEEECCCHHHHHHHHHCCCCCCCCCEECCCCEEEECCHHHHHHHHHHHHHHCC
RVLMPSPSYTTHTVGEIYHAQSAPSLFRLKPEDRWYPDIDEMRMHVRYNPNIAAILIINP
EEEECCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHHCEEEEEECCCEEEEEEECC
DNPTGMVYTREMLEQIVEVARENNLFIIADEVYTNIAYNGETTVPICDVIGDVPAISMRG
CCCCCEEEHHHHHHHHHHHHHCCCEEEEEHHHHHEEEECCCCCCHHHHHHCCCCCEECCC
ISKELPWPGSRCGWIEVYNSDKDEHFRKYVNLILNGKMNEVCSTTLPQTVFPAIMRHPEY
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHCCCCC
QPYLAERIARYEKMSNITYDYLSQVPALQVNRTNGAFYMAVAFREGLLNHRQSLPIANAD
CHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHHHHCCCCCCHH
VREYIQGLVNQPGVSPDKRFVYHMLAATGICVVPLSSFSTPLQGFRVTLLEKDEDECRRI
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEEECCHHHHHHH
YQTLAEKIGEYLQS
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]