Click here to switch to the map view.

The map label for this gene is capA [H]

Identifier: 118579054

GI number: 118579054

Start: 652328

End: 653350

Strand: Reverse

Name: capA [H]

Synonym: Ppro_0615

Alternate gene names: 118579054

Gene position: 653350-652328 (Counterclockwise)

Preceding gene: 118579062

Following gene: 118579053

Centisome position: 16.3

GC content: 65.49

Gene sequence:

>1023_bases
ATGAAATCAGCGATCATCCTGTTCATAACCGCCCTGTTGCCGCTTCTGTGCCCCGCCGTTGCCACCGCACAGGAGATCGT
CGTCAACGCCGTTGGCGACATCATGCTGGCCGGCCGTTGGACGGCCGACCTGAGAGCAGCGGGCTACGACCCCCTCTTTG
ACAACCTCAGGGACGAACTGGCCAGGGGCGACATCAACCTGGCCAACCTGGAGTCGCCCCTGGCCCGTTGCGGCAGGGAG
TTCACCACCAAGAAGTTCCGTTTCCGGGGCGAACCGGCGGTTGCCCCGGCCCTGCGCAGGGCCGGCTTCAACCTGGTCAC
CCTGGCCAACAACCACAGCATGGATTTCGGCTGGCCGGCCCTGGCCGAGACCCGCGGCCACCTGAAGGATGCAGGTATCG
CCTGGATCGGCGCCGGAGAAAACCTGGAGCAGGCCCGCCGCATGGCGCTCTTCACGGTCAGAGGGAAGCGGGTCGCCTTT
CTGGGCTATTCCCTGACCCAGCCGCTGGAATTCTTTGCCGCCCCCCGGCGTCCCGGAACCGCACCCGGTTATGCCAAGCT
GGTGGCGGCCGACGTGGCGGCCGCCCGCGGAAAGGCCGATTACGTGATCGTCTCATTTCACTGGGGCAGGGAAGCCAGCA
CAACGGTGCAGGCCTACCAGCGCGACACGGCCCACCGGGCCATCGATGCTGGCGCCGACGTTATCATCGGGCACCACCCC
CATGTGCTGCAAGGGGTGGAGCGCTACCGGCGGGGCATCATCTTCTACAGCCTGGGCAACTTCGCCTTTGCCAGCACAAG
CACCATTGCCGATGTGTCTGCCCTGGTCCGCCTGCGGCTGGACGGCAGGCAGCGCCAGGCCGAACTGCTGCCGCTGGATG
TGCTGTACCGGCGGGTCAGGTTCCAGCCACGCCTGTTGAAGGGGGACCGGGGAGCCGCCGTGATCAGCAGGATCAACGAA
CTGTCCCGCCCTTTCAGGACCGAGATACGTGAGATGGGCGGAAGATACGTGGTGCTGTTTTAG

Upstream 100 bases:

>100_bases
ATGAATTTCATGTCGAGCATCTTAATTCACCTTTATTTTTTATGGTCAAGCGTGTATGTAGTAGCACCGCCCACGCCTCC
CGTCAATCCCAAAGAGCCCT

Downstream 100 bases:

>100_bases
TCAGCCACGAACTTGGCCCCTTCCAGAGACAGGGACCCCGAACAGCAATAGAACGCGGATGCCCCCGAGCCGGCAACGCC
GGAAGCAACCGAAAACCAAA

Product: capsule biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKSAIILFITALLPLLCPAVATAQEIVVNAVGDIMLAGRWTADLRAAGYDPLFDNLRDELARGDINLANLESPLARCGRE
FTTKKFRFRGEPAVAPALRRAGFNLVTLANNHSMDFGWPALAETRGHLKDAGIAWIGAGENLEQARRMALFTVRGKRVAF
LGYSLTQPLEFFAAPRRPGTAPGYAKLVAADVAAARGKADYVIVSFHWGREASTTVQAYQRDTAHRAIDAGADVIIGHHP
HVLQGVERYRRGIIFYSLGNFAFASTSTIADVSALVRLRLDGRQRQAELLPLDVLYRRVRFQPRLLKGDRGAAVISRINE
LSRPFRTEIREMGGRYVVLF

Sequences:

>Translated_340_residues
MKSAIILFITALLPLLCPAVATAQEIVVNAVGDIMLAGRWTADLRAAGYDPLFDNLRDELARGDINLANLESPLARCGRE
FTTKKFRFRGEPAVAPALRRAGFNLVTLANNHSMDFGWPALAETRGHLKDAGIAWIGAGENLEQARRMALFTVRGKRVAF
LGYSLTQPLEFFAAPRRPGTAPGYAKLVAADVAAARGKADYVIVSFHWGREASTTVQAYQRDTAHRAIDAGADVIIGHHP
HVLQGVERYRRGIIFYSLGNFAFASTSTIADVSALVRLRLDGRQRQAELLPLDVLYRRVRFQPRLLKGDRGAAVISRINE
LSRPFRTEIREMGGRYVVLF
>Mature_340_residues
MKSAIILFITALLPLLCPAVATAQEIVVNAVGDIMLAGRWTADLRAAGYDPLFDNLRDELARGDINLANLESPLARCGRE
FTTKKFRFRGEPAVAPALRRAGFNLVTLANNHSMDFGWPALAETRGHLKDAGIAWIGAGENLEQARRMALFTVRGKRVAF
LGYSLTQPLEFFAAPRRPGTAPGYAKLVAADVAAARGKADYVIVSFHWGREASTTVQAYQRDTAHRAIDAGADVIIGHHP
HVLQGVERYRRGIIFYSLGNFAFASTSTIADVSALVRLRLDGRQRQAELLPLDVLYRRVRFQPRLLKGDRGAAVISRINE
LSRPFRTEIREMGGRYVVLF

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 37555; Mature: 37555

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAIILFITALLPLLCPAVATAQEIVVNAVGDIMLAGRWTADLRAAGYDPLFDNLRDEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCHHHHHHHHHH
ARGDINLANLESPLARCGREFTTKKFRFRGEPAVAPALRRAGFNLVTLANNHSMDFGWPA
HHCCCCHHHHHHHHHHHCHHHHCHHHEECCCCCHHHHHHHCCCEEEEEECCCCCCCCCCH
LAETRGHLKDAGIAWIGAGENLEQARRMALFTVRGKRVAFLGYSLTQPLEFFAAPRRPGT
HHHHHCCCCCCCEEEEECCCCHHHHHHHEEEEECCCEEEEECCCHHCCHHHHCCCCCCCC
APGYAKLVAADVAAARGKADYVIVSFHWGREASTTVQAYQRDTAHRAIDAGADVIIGHHP
CCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCC
HVLQGVERYRRGIIFYSLGNFAFASTSTIADVSALVRLRLDGRQRQAELLPLDVLYRRVR
HHHHHHHHHHCCEEEEEECCEEECCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHC
FQPRLLKGDRGAAVISRINELSRPFRTEIREMGGRYVVLF
CCCCEECCCCCHHHHHHHHHHCCHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MKSAIILFITALLPLLCPAVATAQEIVVNAVGDIMLAGRWTADLRAAGYDPLFDNLRDEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCHHHHHHHHHH
ARGDINLANLESPLARCGREFTTKKFRFRGEPAVAPALRRAGFNLVTLANNHSMDFGWPA
HHCCCCHHHHHHHHHHHCHHHHCHHHEECCCCCHHHHHHHCCCEEEEEECCCCCCCCCCH
LAETRGHLKDAGIAWIGAGENLEQARRMALFTVRGKRVAFLGYSLTQPLEFFAAPRRPGT
HHHHHCCCCCCCEEEEECCCCHHHHHHHEEEEECCCEEEEECCCHHCCHHHHCCCCCCCC
APGYAKLVAADVAAARGKADYVIVSFHWGREASTTVQAYQRDTAHRAIDAGADVIIGHHP
CCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCC
HVLQGVERYRRGIIFYSLGNFAFASTSTIADVSALVRLRLDGRQRQAELLPLDVLYRRVR
HHHHHHHHHHCCEEEEEECCEEECCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHC
FQPRLLKGDRGAAVISRINELSRPFRTEIREMGGRYVVLF
CCCCEECCCCCHHHHHHHHHHCCHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]