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The map label for this gene is atpA1

Identifier: 118579043

GI number: 118579043

Start: 639057

End: 640565

Strand: Direct

Name: atpA1

Synonym: Ppro_0604

Alternate gene names: 118579043

Gene position: 639057-640565 (Clockwise)

Preceding gene: 118579042

Following gene: 118579044

Centisome position: 15.94

GC content: 62.62

Gene sequence:

>1509_bases
ATGAAAATCAGAGCGGAAGAGATCAGCGAGATCATCAAGAAACAGATCAGAGAGTACGGCAAGGAGGTCGAGGTCTCGGA
GACCGGCACGATCATCTCCATCGGCGACGGCATTGCCCGTATTCACGGCCTTTCGGGCGCCATGGCGGGGGAGTTGCTGG
AATTTCCCGGCGGCGTTTCGGGCATGGTCCTCAACCTGGAGGAGGACAATGTCGGTGCCGCGGTCCTGGGTGAATTCACC
GCGATCAAGGAGGGTCACACCGTCAAGCGCACCGGCCGCATTGCCGAGGTTCCTGTGGGCGAAGCCCTGATCGGGCGGGT
GGTCAACGCCATCGGCGAGCCGATCGACGGCAAGGGGCCGATCAAAACCGACACCTTCAGCAAGGTGGAGATCAAGGCTC
CCGGCATCGTTGCCCGCAAATCGGTTGATCAGCCCATGGCCTCCGGCCTCAAGGCCGTCGACGCCATGGTTCCCATCGGC
CGCGGCCAGCGCGAACTGATCATCGGCGACCGCCAGACTGGCAAGACAGCCGTAGCAGTGGATACGATCATCAACCAGAA
GGGTGGGGACGTGATCTGCATCTACGTTGCCATCGGCCAGAAGCGCTCCACCGTGGCCCAAGTGGTGGCCAAGCTCTCCG
ATCACGGCGCCATGGACTACACCATCGTCGTTGCCGCTTCCGCATCCGAGTCGGCGCCGCTCCAGTTCATCGCCCCCTAC
AGCGGGGTCACCATGGGCGAGTACTTCCGCGACAAAGGCCAGCACGCCCTGATCATCTATGACGACCTTTCCAAGCAGGC
TGTAGCCTACCGCCAGCTGTCGCTGCTGCTGCGCCGCCCTCCGGGGCGCGAGGCCTACCCCGGTGACGTCTTCTACCTGC
ACAGCCGTCTGCTGGAACGCGCCTGCAAGCTGTCCGACGAGTGCGGCGGCGGTTCGCTCACCGCGCTTCCCATCATCGAG
ACCCAGGCCGGCGACGTCTCCGCTTACATCCCGACCAACGTCATCTCCATCACCGACGGCCAGATCTATCTGGAATCGGA
CCTGTTCTTCTCCGGCGTGCGTCCGGCCATCAACGTCGGCCTCTCCGTCTCCCGCGTCGGTGGCAAGGCGCAGACCAAAT
CCATGAAGCAGGTTGCCGGCACCCTGCGGCTGAACCTGGCCCAGTACCGCGAGATGGCGGCCTTTGCCCAGTTCGGTTCC
GACCTGGACAAGGCGACCCAGATGCAGCTTGCCCGTGGCGAGCGTCTGGTGGAGATCCTGAAACAGCCGCAGTACCGCCC
GCTGTCCAACGAAAAGCAGGTGCTGATCATCTTTGCCGCCAACAACGGCTTCCTGGACGAGCTGCCGGTCTCCACGCTGA
GGCGTTACGAGGATGAGATGTACGCATTCTTCGACAACCGCCAGGCCGACCTGCTGTCGGAGCTGCGCGACAAGAAAGCC
ATCGATGACGAGCTGAAGAAGCGCATCGTGGCTGCCCTGGAGCAGTTCAAGAAAGAATTCAGCGCGTAA

Upstream 100 bases:

>100_bases
GGCGGTGTTGTCGTTCAGATCGGTGATACGGTCTACGACAGCAGTGTAAAGACGCAACTCAAGCGGATACAAGATCAATT
ACAGAAGGGGTAATGCTCCC

Downstream 100 bases:

>100_bases
GCACAAGGACGGACTACAACCATGGCGAGCCTCAAGAGCATAAAGAAACGGATTGTCTCGGTAAAGAATACCTACCAGAT
CACCAAGGCCATGAAGATGG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKIRAEEISEIIKKQIREYGKEVEVSETGTIISIGDGIARIHGLSGAMAGELLEFPGGVSGMVLNLEEDNVGAAVLGEFT
AIKEGHTVKRTGRIAEVPVGEALIGRVVNAIGEPIDGKGPIKTDTFSKVEIKAPGIVARKSVDQPMASGLKAVDAMVPIG
RGQRELIIGDRQTGKTAVAVDTIINQKGGDVICIYVAIGQKRSTVAQVVAKLSDHGAMDYTIVVAASASESAPLQFIAPY
SGVTMGEYFRDKGQHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERACKLSDECGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLESDLFFSGVRPAINVGLSVSRVGGKAQTKSMKQVAGTLRLNLAQYREMAAFAQFGS
DLDKATQMQLARGERLVEILKQPQYRPLSNEKQVLIIFAANNGFLDELPVSTLRRYEDEMYAFFDNRQADLLSELRDKKA
IDDELKKRIVAALEQFKKEFSA

Sequences:

>Translated_502_residues
MKIRAEEISEIIKKQIREYGKEVEVSETGTIISIGDGIARIHGLSGAMAGELLEFPGGVSGMVLNLEEDNVGAAVLGEFT
AIKEGHTVKRTGRIAEVPVGEALIGRVVNAIGEPIDGKGPIKTDTFSKVEIKAPGIVARKSVDQPMASGLKAVDAMVPIG
RGQRELIIGDRQTGKTAVAVDTIINQKGGDVICIYVAIGQKRSTVAQVVAKLSDHGAMDYTIVVAASASESAPLQFIAPY
SGVTMGEYFRDKGQHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERACKLSDECGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLESDLFFSGVRPAINVGLSVSRVGGKAQTKSMKQVAGTLRLNLAQYREMAAFAQFGS
DLDKATQMQLARGERLVEILKQPQYRPLSNEKQVLIIFAANNGFLDELPVSTLRRYEDEMYAFFDNRQADLLSELRDKKA
IDDELKKRIVAALEQFKKEFSA
>Mature_502_residues
MKIRAEEISEIIKKQIREYGKEVEVSETGTIISIGDGIARIHGLSGAMAGELLEFPGGVSGMVLNLEEDNVGAAVLGEFT
AIKEGHTVKRTGRIAEVPVGEALIGRVVNAIGEPIDGKGPIKTDTFSKVEIKAPGIVARKSVDQPMASGLKAVDAMVPIG
RGQRELIIGDRQTGKTAVAVDTIINQKGGDVICIYVAIGQKRSTVAQVVAKLSDHGAMDYTIVVAASASESAPLQFIAPY
SGVTMGEYFRDKGQHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERACKLSDECGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLESDLFFSGVRPAINVGLSVSRVGGKAQTKSMKQVAGTLRLNLAQYREMAAFAQFGS
DLDKATQMQLARGERLVEILKQPQYRPLSNEKQVLIIFAANNGFLDELPVSTLRRYEDEMYAFFDNRQADLLSELRDKKA
IDDELKKRIVAALEQFKKEFSA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=63.0952380952381, Blast_Score=641, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=63.0952380952381, Blast_Score=641, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=343, Percent_Identity=27.4052478134111, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913426, Length=368, Percent_Identity=26.3586956521739, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI32189394, Length=370, Percent_Identity=24.5945945945946, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI19913424, Length=247, Percent_Identity=25.9109311740891, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790172, Length=508, Percent_Identity=58.4645669291339, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI1788251, Length=325, Percent_Identity=29.2307692307692, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790170, Length=387, Percent_Identity=24.8062015503876, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=503, Percent_Identity=63.6182902584493, Blast_Score=647, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=503, Percent_Identity=63.6182902584493, Blast_Score=646, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=503, Percent_Identity=59.8409542743539, Blast_Score=593, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17570191, Length=331, Percent_Identity=26.2839879154079, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=364, Percent_Identity=24.4505494505494, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=350, Percent_Identity=24.5714285714286, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=70, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988068, Length=71, Percent_Identity=45.0704225352113, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=507, Percent_Identity=60.7495069033531, Blast_Score=634, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=331, Percent_Identity=27.190332326284, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=370, Percent_Identity=24.8648648648649, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=61.5841584158416, Blast_Score=629, Evalue=1e-180,
Organism=Drosophila melanogaster, GI281361666, Length=333, Percent_Identity=26.4264264264264, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24646341, Length=333, Percent_Identity=26.4264264264264, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17136796, Length=333, Percent_Identity=26.4264264264264, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24638766, Length=370, Percent_Identity=25.6756756756757, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574560, Length=379, Percent_Identity=25.3298153034301, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583988, Length=266, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583986, Length=266, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583984, Length=266, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583992, Length=266, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129479, Length=240, Percent_Identity=27.5, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_PELPD (A1ALL5)

Other databases:

- EMBL:   CP000482
- EMBL:   CP000482
- RefSeq:   YP_900293.1
- RefSeq:   YP_901178.1
- ProteinModelPortal:   A1ALL5
- SMR:   A1ALL5
- STRING:   A1ALL5
- GeneID:   4572198
- GeneID:   4572385
- GenomeReviews:   CP000482_GR
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0604
- KEGG:   ppd:Ppro_1505
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   A1ALL5
- ProtClustDB:   PRK09281
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54481; Mature: 54481

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRAEEISEIIKKQIREYGKEVEVSETGTIISIGDGIARIHGLSGAMAGELLEFPGGVS
CCCCHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCCC
GMVLNLEEDNVGAAVLGEFTAIKEGHTVKRTGRIAEVPVGEALIGRVVNAIGEPIDGKGP
EEEEEECCCCCCHHHHHHHHHHCCCCEEHHCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
IKTDTFSKVEIKAPGIVARKSVDQPMASGLKAVDAMVPIGRGQRELIIGDRQTGKTAVAV
CCCCCCCEEEEECCCEEEHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEE
DTIINQKGGDVICIYVAIGQKRSTVAQVVAKLSDHGAMDYTIVVAASASESAPLQFIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCC
SGVTMGEYFRDKGQHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ACKLSDECGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLESDLFFSGVRPAINVG
HHCCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEECCCCCCCCCHHHHCC
LSVSRVGGKAQTKSMKQVAGTLRLNLAQYREMAAFAQFGSDLDKATQMQLARGERLVEIL
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KQPQYRPLSNEKQVLIIFAANNGFLDELPVSTLRRYEDEMYAFFDNRQADLLSELRDKKA
HCCCCCCCCCCCEEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IDDELKKRIVAALEQFKKEFSA
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIRAEEISEIIKKQIREYGKEVEVSETGTIISIGDGIARIHGLSGAMAGELLEFPGGVS
CCCCHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCCC
GMVLNLEEDNVGAAVLGEFTAIKEGHTVKRTGRIAEVPVGEALIGRVVNAIGEPIDGKGP
EEEEEECCCCCCHHHHHHHHHHCCCCEEHHCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
IKTDTFSKVEIKAPGIVARKSVDQPMASGLKAVDAMVPIGRGQRELIIGDRQTGKTAVAV
CCCCCCCEEEEECCCEEEHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEE
DTIINQKGGDVICIYVAIGQKRSTVAQVVAKLSDHGAMDYTIVVAASASESAPLQFIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCC
SGVTMGEYFRDKGQHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ACKLSDECGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLESDLFFSGVRPAINVG
HHCCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEECCCCCCCCCHHHHCC
LSVSRVGGKAQTKSMKQVAGTLRLNLAQYREMAAFAQFGSDLDKATQMQLARGERLVEIL
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KQPQYRPLSNEKQVLIIFAANNGFLDELPVSTLRRYEDEMYAFFDNRQADLLSELRDKKA
HCCCCCCCCCCCEEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IDDELKKRIVAALEQFKKEFSA
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA