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The map label for this gene is atpB1

Identifier: 118579038

GI number: 118579038

Start: 636313

End: 637002

Strand: Direct

Name: atpB1

Synonym: Ppro_0599

Alternate gene names: 118579038

Gene position: 636313-637002 (Clockwise)

Preceding gene: 118579037

Following gene: 118579039

Centisome position: 15.88

GC content: 56.96

Gene sequence:

>690_bases
ATGGTCCACCCGTTACTCTTTCTCGAATTTTTCCGCAAGCTGCTCGAACCGCTGCACATGTCCGAGGCCGGTGCGGACGC
CGTTGCCTACACCTGGCTTATTATGCTGTTACTGCTGCTGTTCTCTTTTCTGGCTACCAGGGCGCTCAAGATGATCCCCT
GTGGATTGCAGAATTTCATGGAAGTTGTTGTCGGTGGCGTTGAGAACATGATCGTCGAGACCATGGGTGAGCATGGCCGC
CCCTACTTCCCGCTGGTGGCCACCGTGGGACTCTTTGTACTGGTTTCCAATCTGATCGGCCTGATCCCCGGGTTTTTCCC
GCCGACGGCCAACATCAACACCACCGCCGCCTGTGCCATAGTGGTGTTCATCGCCACCCATGTGGTGGGTATAAAGCGGC
ATGGCATTGGCTACATAAAACACTTCTGCGGCCCCATTCTCTGGCTGGCGCCGGTCATGTTCTTCATCGAGGTCATCGGA
CACCTGAGCCGTCCGCTTTCCCTGACCCTGCGTCTGTTCGGCAACATGAACGGCCACGAACTGGTCCTGATCATCTTCTT
CGGCCTGGCGCCCTTCCTGGTGCCGCTGCCGATGATGCTGATGGGGGTGCTGGTCTCCTTCATTCAGGCGTTCGTCTTCA
TGCTGCTGACGATGATCTACATCCAGGGTTCGCTTGAAGAGGCCCACTGA

Upstream 100 bases:

>100_bases
TTCATAAACAAGTTTTTTGCTGTTTCTTTTTTGGTGATTGATGTCGAAGGCATGGCCTGCTTGTCCAGGCCGTGAAATTT
TGCTGGGGGGTAGGTTCGCC

Downstream 100 bases:

>100_bases
TCCACCGGTTGATTCACAACAATTATCAAGATCCTATACTGCTTAGGATACATCACACTCCGAGGGGAGAACGAACCATG
AACTTTTTCACTATGTGTGT

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a 1; F-ATPase subunit 6 1

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MVHPLLFLEFFRKLLEPLHMSEAGADAVAYTWLIMLLLLLFSFLATRALKMIPCGLQNFMEVVVGGVENMIVETMGEHGR
PYFPLVATVGLFVLVSNLIGLIPGFFPPTANINTTAACAIVVFIATHVVGIKRHGIGYIKHFCGPILWLAPVMFFIEVIG
HLSRPLSLTLRLFGNMNGHELVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH

Sequences:

>Translated_229_residues
MVHPLLFLEFFRKLLEPLHMSEAGADAVAYTWLIMLLLLLFSFLATRALKMIPCGLQNFMEVVVGGVENMIVETMGEHGR
PYFPLVATVGLFVLVSNLIGLIPGFFPPTANINTTAACAIVVFIATHVVGIKRHGIGYIKHFCGPILWLAPVMFFIEVIG
HLSRPLSLTLRLFGNMNGHELVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH
>Mature_229_residues
MVHPLLFLEFFRKLLEPLHMSEAGADAVAYTWLIMLLLLLFSFLATRALKMIPCGLQNFMEVVVGGVENMIVETMGEHGR
PYFPLVATVGLFVLVSNLIGLIPGFFPPTANINTTAACAIVVFIATHVVGIKRHGIGYIKHFCGPILWLAPVMFFIEVIG
HLSRPLSLTLRLFGNMNGHELVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=208, Percent_Identity=31.7307692307692, Blast_Score=85, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6226527, Length=214, Percent_Identity=26.1682242990654, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP61_PELPD (A1ALL0)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900288.1
- ProteinModelPortal:   A1ALL0
- SMR:   A1ALL0
- STRING:   A1ALL0
- GeneID:   4572380
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0599
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   DAQKHLS
- PhylomeDB:   A1ALL0
- ProtClustDB:   CLSK924394
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 25402; Mature: 25402

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21678b74)-; HASH(0x210c8930)-; HASH(0x22cce2a8)-; HASH(0x230ae5c0)-; HASH(0x21fee640)-; HASH(0x2111471c)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHPLLFLEFFRKLLEPLHMSEAGADAVAYTWLIMLLLLLFSFLATRALKMIPCGLQNFM
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVVGGVENMIVETMGEHGRPYFPLVATVGLFVLVSNLIGLIPGFFPPTANINTTAACAI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
VVFIATHVVGIKRHGIGYIKHFCGPILWLAPVMFFIEVIGHLSRPLSLTLRLFGNMNGHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHH
LVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCH
>Mature Secondary Structure
MVHPLLFLEFFRKLLEPLHMSEAGADAVAYTWLIMLLLLLFSFLATRALKMIPCGLQNFM
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVVGGVENMIVETMGEHGRPYFPLVATVGLFVLVSNLIGLIPGFFPPTANINTTAACAI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
VVFIATHVVGIKRHGIGYIKHFCGPILWLAPVMFFIEVIGHLSRPLSLTLRLFGNMNGHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHH
LVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA