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The map label for this gene is ppiC [H]

Identifier: 118579009

GI number: 118579009

Start: 605468

End: 606199

Strand: Direct

Name: ppiC [H]

Synonym: Ppro_0570

Alternate gene names: 118579009

Gene position: 605468-606199 (Clockwise)

Preceding gene: 118579006

Following gene: 118579021

Centisome position: 15.11

GC content: 64.89

Gene sequence:

>732_bases
ATGCCCGCTACCGCCCGTCACATCCTCGTTGATACCGAGGACCTCTGCCTGAAGCTCAAGACCGAGATCGAAGCCGGCGC
CGACTTTGCCGACGTTGCCCGCCGCGAATCCTCATGCCCGTCTCGCCAGCAGGGGGGCGACCTGGGCACGTTCAACCCCG
GCCAGATGGTGCCCGAGTTCGATCACGCGGTCTTTACCGGGGAGGTGAACAAGCTGCTCGGCCCGGTTCAGACCCAGTTC
GGCTATCACCTGATCGAGGTGACCCGCCGCTGGGAGGAGGCGGCTGCGGAAGCCTCTCCGGCGGAGAACGCCCTGGACCG
TGCCCTGGCGGCGCTGCACCAGGATGTGAATGATCCCAAGGCGCAGTCGGCCTTTTACGGCACCTTCCTCAACACGACCT
TCTGCGTGCCGACCCTGGATTCGAAGGAACTGGACGGCGAAGAAGCGGGCGCGGAGGAGCGGGTGCTTCCGCTGGTCCTT
GAGGCCGACGGGACCAGGTACCTTATTGTTTTCAGCAGCGAAGCTCGCCTGACGGAGTGGGCCGGCCGTTCCGTCGACTG
GGCTCCGGTTCCGGGGCACGTACTGGCGACCACCGCCATGCCGCCGCTGCACATCGCCATGAACGTGGGCACCGAATACT
CGAAACAGTTCAACCCCGAAGAAATCGCCTGGCTCAGGGAGGTGGTGAAGCGCAGCCGGCAGACGGAAAGCGGGGAGGAG
CAAACGAACTGA

Upstream 100 bases:

>100_bases
GCGGCGACGTGCCAACCACGGGCTCACCCGATAACGGTTGTCAGCGTCGGTCGACTCGGCTACTATGCCGCACACTATTT
TAGCCGTTCAAGGAGCATCC

Downstream 100 bases:

>100_bases
AGCGGGCGTCAACCTGCGTGAATAACTGTTCGGAGACGGCCCCGGTCGGGGCTCCTCCGAACTTCACCATGCTCTGACCG
TTCTCTCCGGTGCCCGGGCG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase C; Parvulin; Rotamase C [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MPATARHILVDTEDLCLKLKTEIEAGADFADVARRESSCPSRQQGGDLGTFNPGQMVPEFDHAVFTGEVNKLLGPVQTQF
GYHLIEVTRRWEEAAAEASPAENALDRALAALHQDVNDPKAQSAFYGTFLNTTFCVPTLDSKELDGEEAGAEERVLPLVL
EADGTRYLIVFSSEARLTEWAGRSVDWAPVPGHVLATTAMPPLHIAMNVGTEYSKQFNPEEIAWLREVVKRSRQTESGEE
QTN

Sequences:

>Translated_243_residues
MPATARHILVDTEDLCLKLKTEIEAGADFADVARRESSCPSRQQGGDLGTFNPGQMVPEFDHAVFTGEVNKLLGPVQTQF
GYHLIEVTRRWEEAAAEASPAENALDRALAALHQDVNDPKAQSAFYGTFLNTTFCVPTLDSKELDGEEAGAEERVLPLVL
EADGTRYLIVFSSEARLTEWAGRSVDWAPVPGHVLATTAMPPLHIAMNVGTEYSKQFNPEEIAWLREVVKRSRQTESGEE
QTN
>Mature_242_residues
PATARHILVDTEDLCLKLKTEIEAGADFADVARRESSCPSRQQGGDLGTFNPGQMVPEFDHAVFTGEVNKLLGPVQTQFG
YHLIEVTRRWEEAAAEASPAENALDRALAALHQDVNDPKAQSAFYGTFLNTTFCVPTLDSKELDGEEAGAEERVLPLVLE
ADGTRYLIVFSSEARLTEWAGRSVDWAPVPGHVLATTAMPPLHIAMNVGTEYSKQFNPEEIAWLREVVKRSRQTESGEEQ
TN

Specific function: PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=88, Percent_Identity=53.4090909090909, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 26756; Mature: 26625

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATARHILVDTEDLCLKLKTEIEAGADFADVARRESSCPSRQQGGDLGTFNPGQMVPEF
CCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCC
DHAVFTGEVNKLLGPVQTQFGYHLIEVTRRWEEAAAEASPAENALDRALAALHQDVNDPK
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCH
AQSAFYGTFLNTTFCVPTLDSKELDGEEAGAEERVLPLVLEADGTRYLIVFSSEARLTEW
HHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHH
AGRSVDWAPVPGHVLATTAMPPLHIAMNVGTEYSKQFNPEEIAWLREVVKRSRQTESGEE
CCCCCCCCCCCCCEEEECCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
QTN
CCC
>Mature Secondary Structure 
PATARHILVDTEDLCLKLKTEIEAGADFADVARRESSCPSRQQGGDLGTFNPGQMVPEF
CCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCC
DHAVFTGEVNKLLGPVQTQFGYHLIEVTRRWEEAAAEASPAENALDRALAALHQDVNDPK
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCH
AQSAFYGTFLNTTFCVPTLDSKELDGEEAGAEERVLPLVLEADGTRYLIVFSSEARLTEW
HHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHH
AGRSVDWAPVPGHVLATTAMPPLHIAMNVGTEYSKQFNPEEIAWLREVVKRSRQTESGEE
CCCCCCCCCCCCCEEEECCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
QTN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]