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The map label for this gene is yiaY [H]

Identifier: 118578993

GI number: 118578993

Start: 590613

End: 591776

Strand: Reverse

Name: yiaY [H]

Synonym: Ppro_0554

Alternate gene names: 118578993

Gene position: 591776-590613 (Counterclockwise)

Preceding gene: 118578994

Following gene: 118578988

Centisome position: 14.76

GC content: 57.3

Gene sequence:

>1164_bases
ATGGCATTAGCAGATCAGACGTTCGGTTTTTTCATCCCTAGCGTAACACTGTTGGGTCTCGGCTGCTCGAAAGAAGCAGG
CGAACAGGCTAAAGCGCTTGGCGCAACGAAACTGTTGATCGTCACCGACGCGGGCCTTGCCAAGATGGGTGTTGCCGACA
CTATCAAAGGCTATGTTGAAGCAGCCGGCCTCCAGGCCGCCATTTACCCCGGTGCAGAGCCGAACCCGACCGACAAGAAC
GTACACGATGGCGTAAAAGCCTATCAGGACAACAAGTGTGATGGCATTATCTCCCTCGGCGGCGGCAGCTCCCATGACTG
CGGCAAGGGTATCGGCCTTGTTATCGCTGGCGGCGGCAACATCCGCGACTACGAAGGCGTCAACAAGTCAACCAAAGTGA
TGCCTCCGTTCCTGGCTATCAACACCACCGCCGGTACCGCCTCCGAAATGACCCGCTTCTGCATCATCACCAACACCGAC
ACCCATGTCAAAATGGCTATCGTTGACTGGCGTGTAACTCCGAACATCGCCATAGATGACCCCCTGATGATGGTTGGCAT
GCCGCCGAAACTGACCGCCGCAACCGGCATGGACGCACTGACCCACGCTGTCGAAGCGTATGTTTCCATCATCGCCAACC
CGATCACCGACGCTTGCGCCATCAAGGCTATCGAACTGATCGCCAAGAACCTGAGCCCGGCTGTTGCCAACGGCGAAGAC
CTGGTTGCCCGTGACGCCATGGCATATGCCGAATATCTGGCCGGTATGGCATTCAACAACGCCAGCCTCGGCTATGTTCA
CTCCATGGCTCACCAGTTGGGCGGTTTCTACAACCTGCCCCACGGCGTCTGCAACGCCATCCTGCTGCCCGTCGTCAGCC
AGTTCAACCTGATCGCCTGCCCGCAGCGTTTTGCCGACATCGCCGTTGCTCTCGGCGAGTGCATCGACGGCCTGTCGGTA
ACCGAAGCCGGCCAGAAAGCCATCGACAGAATCAAGTCCCTGTCCGCTTCCATCGGCATTCCTGCCAACCTGACCGAGCT
GGGCGTAAAAGAAGCCGACCTGAAGATTATGTCCGAAAACGCCAAGAAAGACGCTTGCCAGCTGACCAACCCGCGTAAAG
CCACGTTGGACGAAGTCATTAGCATCTTCAAAGCTGCTCTGTAA

Upstream 100 bases:

>100_bases
ATAAGCACAATCTCTGAGTTTCAAACTGTATGCCAACACCAAGAAGCGCATACAGATTCCTGCAGGCAGGCAACATCTCA
ATTCAAAGGAGAATGTACAC

Downstream 100 bases:

>100_bases
TCAACGCAAGAATACTCTGCATGTATTGTTTTTTGATGTGCCGGGCCAGTGGTAACAATTTGTGCCCGATATGGTCCATT
CTTAGAGACTGGCCCGGTCC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MALADQTFGFFIPSVTLLGLGCSKEAGEQAKALGATKLLIVTDAGLAKMGVADTIKGYVEAAGLQAAIYPGAEPNPTDKN
VHDGVKAYQDNKCDGIISLGGGSSHDCGKGIGLVIAGGGNIRDYEGVNKSTKVMPPFLAINTTAGTASEMTRFCIITNTD
THVKMAIVDWRVTPNIAIDDPLMMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSPAVANGED
LVARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIACPQRFADIAVALGECIDGLSV
TEAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSENAKKDACQLTNPRKATLDEVISIFKAAL

Sequences:

>Translated_387_residues
MALADQTFGFFIPSVTLLGLGCSKEAGEQAKALGATKLLIVTDAGLAKMGVADTIKGYVEAAGLQAAIYPGAEPNPTDKN
VHDGVKAYQDNKCDGIISLGGGSSHDCGKGIGLVIAGGGNIRDYEGVNKSTKVMPPFLAINTTAGTASEMTRFCIITNTD
THVKMAIVDWRVTPNIAIDDPLMMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSPAVANGED
LVARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIACPQRFADIAVALGECIDGLSV
TEAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSENAKKDACQLTNPRKATLDEVISIFKAAL
>Mature_386_residues
ALADQTFGFFIPSVTLLGLGCSKEAGEQAKALGATKLLIVTDAGLAKMGVADTIKGYVEAAGLQAAIYPGAEPNPTDKNV
HDGVKAYQDNKCDGIISLGGGSSHDCGKGIGLVIAGGGNIRDYEGVNKSTKVMPPFLAINTTAGTASEMTRFCIITNTDT
HVKMAIVDWRVTPNIAIDDPLMMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSPAVANGEDL
VARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIACPQRFADIAVALGECIDGLSVT
EAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSENAKKDACQLTNPRKATLDEVISIFKAAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=374, Percent_Identity=27.807486631016, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=56.0846560846561, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1789163, Length=373, Percent_Identity=41.8230563002681, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI87082107, Length=379, Percent_Identity=35.3562005277045, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787493, Length=381, Percent_Identity=33.5958005249344, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789386, Length=388, Percent_Identity=24.2268041237113, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537053, Length=416, Percent_Identity=23.0769230769231, Blast_Score=117, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6321181, Length=381, Percent_Identity=50.6561679790026, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24657991, Length=413, Percent_Identity=26.3922518159806, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40339; Mature: 40208

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALADQTFGFFIPSVTLLGLGCSKEAGEQAKALGATKLLIVTDAGLAKMGVADTIKGYVE
CCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHCCEEEEEEECCCHHHHCHHHHHHHHHH
AAGLQAAIYPGAEPNPTDKNVHDGVKAYQDNKCDGIISLGGGSSHDCGKGIGLVIAGGGN
HCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEECCCC
IRDYEGVNKSTKVMPPFLAINTTAGTASEMTRFCIITNTDTHVKMAIVDWRVTPNIAIDD
CCCCCCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEEEEECCCCEECC
PLMMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSPAVANGED
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCH
LVARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIAC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEC
PQRFADIAVALGECIDGLSVTEAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSEN
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHEECCC
AKKDACQLTNPRKATLDEVISIFKAAL
CCHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALADQTFGFFIPSVTLLGLGCSKEAGEQAKALGATKLLIVTDAGLAKMGVADTIKGYVE
CCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHCCEEEEEEECCCHHHHCHHHHHHHHHH
AAGLQAAIYPGAEPNPTDKNVHDGVKAYQDNKCDGIISLGGGSSHDCGKGIGLVIAGGGN
HCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEECCCC
IRDYEGVNKSTKVMPPFLAINTTAGTASEMTRFCIITNTDTHVKMAIVDWRVTPNIAIDD
CCCCCCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEEEEECCCCEECC
PLMMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSPAVANGED
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCH
LVARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIAC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEC
PQRFADIAVALGECIDGLSVTEAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSEN
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHEECCC
AKKDACQLTNPRKATLDEVISIFKAAL
CCHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]