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The map label for this gene is phoP [H]

Identifier: 118578946

GI number: 118578946

Start: 530170

End: 530880

Strand: Reverse

Name: phoP [H]

Synonym: Ppro_0507

Alternate gene names: 118578946

Gene position: 530880-530170 (Counterclockwise)

Preceding gene: 118578947

Following gene: 118578945

Centisome position: 13.25

GC content: 64.14

Gene sequence:

>711_bases
ATGAACAGGGATACGGAAAAACCGCACATCATGCTGGTCGAGGACGAGATTCACCTGGCGCGGGGGATCTGTTTCAACCT
GGAGGAAGATGGATGCCGGATCAGCCACTTCGCCACCGGCGAGAAGGCACTGGAAGCGCTGCAGTTCGAGCATTTCGACC
TGATCATCCTGGACGTGATGCTCCCCGGCATGGACGGCTTCCAGGTCTGCCAGTCGGTGCGCCGGATGGACGGGCGGGTG
CCGATCCTGATGCTCACCGCCCGCTCCGAGGAGAGCGACCGGGTGCACGGCCTGGAGACCGGCGCCGACGACTACCTGAC
CAAGCCGTTCAACCTGGTGGAATTCCTGCTGCGGGTCAAGGGGATGCTGCGCCGCTCCTCCTGGTACCGTCCCGACCCGG
TGGAGGAGGGGTATTGCTTCGGCTCCAACGAGGTGTTCCTGCTCTCCTACCGCGCCCGCACCGCCCAGGGAGAGATCGAC
CTGACCGAGATGGAGGTGAGGGTACTGTCGATCTTCTTCCAGAAGGAGGGTCAGGCCATCCCGCGGGGGGAGCTGCTCCA
GAAGGTGTGGGGCTACAGCAGCGACACTGAGACCAGGACCCTGGACAACTTTATCGTCCGCCTGCGCCGCTACTTCGAGC
CGGACCCGGCCAAGCCGACGCACTTCCAGACCGTGCGCGGGGTGGGGTACAGGTTCAGCAGGAAGGGGTAG

Upstream 100 bases:

>100_bases
GGGGATACGGCGGCACGGTAACGGCGGAGAGCACAGGCATTGGCCAGGGCTGCACCTTTACCATCACCCTGCCCAAACCA
CAGACAAAGGGTAGCTGAAG

Downstream 100 bases:

>100_bases
GGTAGCGCTTTTCCAGGAACCCGGGGAACATGGGGGCATCATGCGCCATCAGCAGCAGGCCTCCACGGAAACCGGCAACC
GCCGAAGGTGAATCCATGAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MNRDTEKPHIMLVEDEIHLARGICFNLEEDGCRISHFATGEKALEALQFEHFDLIILDVMLPGMDGFQVCQSVRRMDGRV
PILMLTARSEESDRVHGLETGADDYLTKPFNLVEFLLRVKGMLRRSSWYRPDPVEEGYCFGSNEVFLLSYRARTAQGEID
LTEMEVRVLSIFFQKEGQAIPRGELLQKVWGYSSDTETRTLDNFIVRLRRYFEPDPAKPTHFQTVRGVGYRFSRKG

Sequences:

>Translated_236_residues
MNRDTEKPHIMLVEDEIHLARGICFNLEEDGCRISHFATGEKALEALQFEHFDLIILDVMLPGMDGFQVCQSVRRMDGRV
PILMLTARSEESDRVHGLETGADDYLTKPFNLVEFLLRVKGMLRRSSWYRPDPVEEGYCFGSNEVFLLSYRARTAQGEID
LTEMEVRVLSIFFQKEGQAIPRGELLQKVWGYSSDTETRTLDNFIVRLRRYFEPDPAKPTHFQTVRGVGYRFSRKG
>Mature_236_residues
MNRDTEKPHIMLVEDEIHLARGICFNLEEDGCRISHFATGEKALEALQFEHFDLIILDVMLPGMDGFQVCQSVRRMDGRV
PILMLTARSEESDRVHGLETGADDYLTKPFNLVEFLLRVKGMLRRSSWYRPDPVEEGYCFGSNEVFLLSYRARTAQGEID
LTEMEVRVLSIFFQKEGQAIPRGELLQKVWGYSSDTETRTLDNFIVRLRRYFEPDPAKPTHFQTVRGVGYRFSRKG

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=39.4736842105263, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=36.8888888888889, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=36.3247863247863, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=35.4260089686099, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=34.841628959276, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=34.8739495798319, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=35.4700854700855, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=33.1896551724138, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=31.2775330396476, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=30.7692307692308, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=32.7433628318584, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=35.2422907488987, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=29.6137339055794, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=28.8702928870293, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=30.5785123966942, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=102, Percent_Identity=32.3529411764706, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=82, Percent_Identity=35.3658536585366, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=28.448275862069, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=103, Percent_Identity=31.0679611650485, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27320; Mature: 27320

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRDTEKPHIMLVEDEIHLARGICFNLEEDGCRISHFATGEKALEALQFEHFDLIILDVM
CCCCCCCCEEEEEECCHHHHCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCCEEEEEEC
LPGMDGFQVCQSVRRMDGRVPILMLTARSEESDRVHGLETGADDYLTKPFNLVEFLLRVK
CCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHH
GMLRRSSWYRPDPVEEGYCFGSNEVFLLSYRARTAQGEIDLTEMEVRVLSIFFQKEGQAI
HHHHHCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
PRGELLQKVWGYSSDTETRTLDNFIVRLRRYFEPDPAKPTHFQTVRGVGYRFSRKG
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEECCCC
>Mature Secondary Structure
MNRDTEKPHIMLVEDEIHLARGICFNLEEDGCRISHFATGEKALEALQFEHFDLIILDVM
CCCCCCCCEEEEEECCHHHHCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCCEEEEEEC
LPGMDGFQVCQSVRRMDGRVPILMLTARSEESDRVHGLETGADDYLTKPFNLVEFLLRVK
CCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHH
GMLRRSSWYRPDPVEEGYCFGSNEVFLLSYRARTAQGEIDLTEMEVRVLSIFFQKEGQAI
HHHHHCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
PRGELLQKVWGYSSDTETRTLDNFIVRLRRYFEPDPAKPTHFQTVRGVGYRFSRKG
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]