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The map label for this gene is nreC [H]

Identifier: 118578818

GI number: 118578818

Start: 388015

End: 388737

Strand: Reverse

Name: nreC [H]

Synonym: Ppro_0376

Alternate gene names: 118578818

Gene position: 388737-388015 (Counterclockwise)

Preceding gene: 118578827

Following gene: 118578817

Centisome position: 9.7

GC content: 60.58

Gene sequence:

>723_bases
ATGTTGTGCAGCCACAGCGCCCCCGTCCCGAAACCGGAAACAAGGCATGGGGACGCACTGAAGGGGATTACCGTGAAAGA
CAATGACACTACTGGAATTCTGGTCGCAAGCGACCAGATCCTGCTGCGCGCCGGATTGCGCGAGTTGCTGCACACAGAGC
CGAACCTTGATGTCGTGGGAGAAGCGCTGGACGAGAATGAAACGATCTATCTAACGGGTCGACTTGAGCCGGACATCGTT
CTAATGGTTGTACTGAACAGGAGAGAGGCCAGCATCGGGGTCACCAAACGACTGAAAGCCCAGCATCCCGACATCGGCGT
TATCCTGGTAACCAGCTGCGAGGATACCACATTCGCCCGGGATATCATCCGGGCCGGCGCCTCCGGCTATCTCCCCACCC
GGGCGGCGCAATCGGAACTGATCAACGCCATTCACGCCATCAGGCGCGGGGACCTCTACATCCACCCTTCCATGACCCGT
TGCCTCCTGTACGGCCAGACATCTCCGGCCGTGGCCAGGGTCCCTCCCCGGAAGCCGCTGACACGCAGGGAAGCAGAGAT
ACTGGGCTACATCGCCCAGGGGCATACCAATCGCCAGATCGCCGAGCTTCTCTTCGTCAGCGTGCGTACCGTCGAGAGTC
ACCGGGCCAGACTGCAGGGGAAACTGAACGCCCACTGCCGCATGGATCTGGTACGGCACGCGGCGAACCTGGACATCAGG
TAG

Upstream 100 bases:

>100_bases
TCCCGCGGTGCAGCCTCACCTCCATCGATGCGGGGGCACTCTCATGACGGCATCGGCAAAAACCGGCACCATGAACCATG
CTTCATAAATAAGTGCTATC

Downstream 100 bases:

>100_bases
CTCTCCACTGAATTTCCCCTCTGTGTTCGGTCATGGGACGGGAATACATCAGTAGTTTATACGTACGGACTCCGCATCAG
CTCCGCAGTTTACCGCGATA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLCSHSAPVPKPETRHGDALKGITVKDNDTTGILVASDQILLRAGLRELLHTEPNLDVVGEALDENETIYLTGRLEPDIV
LMVVLNRREASIGVTKRLKAQHPDIGVILVTSCEDTTFARDIIRAGASGYLPTRAAQSELINAIHAIRRGDLYIHPSMTR
CLLYGQTSPAVARVPPRKPLTRREAEILGYIAQGHTNRQIAELLFVSVRTVESHRARLQGKLNAHCRMDLVRHAANLDIR

Sequences:

>Translated_240_residues
MLCSHSAPVPKPETRHGDALKGITVKDNDTTGILVASDQILLRAGLRELLHTEPNLDVVGEALDENETIYLTGRLEPDIV
LMVVLNRREASIGVTKRLKAQHPDIGVILVTSCEDTTFARDIIRAGASGYLPTRAAQSELINAIHAIRRGDLYIHPSMTR
CLLYGQTSPAVARVPPRKPLTRREAEILGYIAQGHTNRQIAELLFVSVRTVESHRARLQGKLNAHCRMDLVRHAANLDIR
>Mature_240_residues
MLCSHSAPVPKPETRHGDALKGITVKDNDTTGILVASDQILLRAGLRELLHTEPNLDVVGEALDENETIYLTGRLEPDIV
LMVVLNRREASIGVTKRLKAQHPDIGVILVTSCEDTTFARDIIRAGASGYLPTRAAQSELINAIHAIRRGDLYIHPSMTR
CLLYGQTSPAVARVPPRKPLTRREAEILGYIAQGHTNRQIAELLFVSVRTVESHRARLQGKLNAHCRMDLVRHAANLDIR

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=29.126213592233, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=30, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=26.8292682926829, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788712, Length=201, Percent_Identity=26.3681592039801, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=29.0816326530612, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26533; Mature: 26533

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCSHSAPVPKPETRHGDALKGITVKDNDTTGILVASDQILLRAGLRELLHTEPNLDVVG
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHH
EALDENETIYLTGRLEPDIVLMVVLNRREASIGVTKRLKAQHPDIGVILVTSCEDTTFAR
HHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCEEEEECCCCHHHHH
DIIRAGASGYLPTRAAQSELINAIHAIRRGDLYIHPSMTRCLLYGQTSPAVARVPPRKPL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCEEECCCCCCC
TRREAEILGYIAQGHTNRQIAELLFVSVRTVESHRARLQGKLNAHCRMDLVRHAANLDIR
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLCSHSAPVPKPETRHGDALKGITVKDNDTTGILVASDQILLRAGLRELLHTEPNLDVVG
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHH
EALDENETIYLTGRLEPDIVLMVVLNRREASIGVTKRLKAQHPDIGVILVTSCEDTTFAR
HHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCEEEEECCCCHHHHH
DIIRAGASGYLPTRAAQSELINAIHAIRRGDLYIHPSMTRCLLYGQTSPAVARVPPRKPL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCEEECCCCCCC
TRREAEILGYIAQGHTNRQIAELLFVSVRTVESHRARLQGKLNAHCRMDLVRHAANLDIR
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]