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The map label for this gene is cisA [H]

Identifier: 118578717

GI number: 118578717

Start: 270281

End: 272023

Strand: Reverse

Name: cisA [H]

Synonym: Ppro_0274

Alternate gene names: 118578717

Gene position: 272023-270281 (Counterclockwise)

Preceding gene: 118578718

Following gene: 118578714

Centisome position: 6.79

GC content: 33.91

Gene sequence:

>1743_bases
ATGAAGGTTGTTGGTTATTGCAGGGTGAGCACACAAGAACAAGCTGTCAACGGAACTTCAATTGAAACACAAAAGCTGCA
TATTCAAAATGAATGTAAAAAACTTGGTTATCAGCTTATTGAGATCTATATTGATGGCGGTGTTTCTGGTAATGATGGTA
ATCGCTTCGCTTTAAATAGACTTCTTGAAGACGCGAAGTTCAAAACATTCAATTGTGTCATGTTTACAAAACCAGACAGG
TTAAGTAGAAATTTGGGATATTCAATAAATGTTGTTAAAAGCTTAGAACAACTCCAAGTCAAAATTCATTGTATTGAGCA
ACCTATAATAAACAAGCCCGGTCTGATGTTTAATATTTTGGGGTCTTTTGCAGAACATGAAAGAGACATGATAAAGGAGA
GAACAGATTCTGGTAGAAAAGCTAAATGGAAATCAGAATCATCAGTTATCGGAAGTCTTCCTTTTGGGTACAAAAAAGTA
AATGGTAAAGTTGAAATTGATGACCTAAATTCACTTATATACAATAGAATAGTAAATATGTATCTTAATCAAAACTATTC
TATGAAAGATATAGCAGTTAAACTAACCGCAGAAGGTATTCCACTACCTGGAGCAAGCAACAATAAACACAGCAATTCAT
GGAGTTCAACAACAATTAGTGATATTCTGAAGAATGATTCTTATACTGGAATTACATATCAAAACAAATACGTATTTGAA
TCAAGAAAGAGCAAAAAAACCAATAAAAGCTACTATGCTGCTACTAATGTAGAAAAAGATAAGAGTGAATGGATAAAAAG
AACATATCCAAAATTGATAGATCAAGATAGGTTTGATAAAATTCAAAAACGCATTTCACTTCAAAAAAAGAAACCCAAAA
AACAGCATTCTGGCCTTAATGAACACTTTATGGCAGATAATACTTTGTACTGTGGCTATTGTGGAACAAGGCTCAGAAAA
CTTAAAACAAATGAAGGAAAACTAAAATATACTTGTCATTGGGCTTATACGACAAAAACTGATTTGTTTTTGAGTAATCG
TAATAAATGTATCTTAAAACCAATTGATGCAAAAGAAGCTGACGATAGAATATTCGATGAAATCACAGAAATTATCTCAG
ATCCTGGACACTTTGCACAGGAATGGCTCAGAGATACAAACATTGATGAGCTTAGTGATAAAGTAAACAGGCTTAATAAA
ATAGAAAATAATCTTCGTAACGCTCTCCTTGACGGCTTTAGACTGGTTCAAGAATCAGATAATCCCGAAATTAAACAAAT
ATATAAGGATGCTTTGCGTAATAAAGAACAAGAATTCTCAGAAGTGCAGAACAGCCTCAAAAATGCAAACAATGAATTAT
TTTTTGCTGTAAACAAAGTGAACCATCTCGCTGAATTTCAAAGTGCTTTAGAGGACGCTGCAAAGAGAGATAAGATTGGC
ATCTATTTTTCAGCAAAAGCGCAATTCAAAACGTTTTTATGCAATTTGCCATTTCAAGAGAAAAAGCGTATTGTTGGCGC
TGTTGTCTCACCAGAAGATGGTGGCAAATATTTAGTTCGCCATCCTACTTTAAACGATATTGCAGACGATACTGATAGCA
TTCCGGAGGATGAACTTTACACTTCTCTTCCTGCAAAGGGTCATATACTTGATGGTATTTTTTCGATAGATCTGAACCGA
ATTCAATCCATCATAAGCAGCTTGAATTACATGGAGTTATTAAGTAGTGCTGTTCCTGGATGA

Upstream 100 bases:

>100_bases
TGCGAGTAATTAAAGAATCACAATATAAATATAATATAATCATCTGATTCCAGAAAACGCCTGTATGATACAAATGAAAT
AAATAATCATGGGGGCAAAA

Downstream 100 bases:

>100_bases
ACTTCCCGAATTCAAAAAGAACGTGCTGGAAGTGCTGCGCCAGCCGCTGGAGGATGGCCGCGTGACCATCTCCCGCTCGC
TGATATCCCTGACCTATCCG

Product: resolvase domain-containing protein

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MKVVGYCRVSTQEQAVNGTSIETQKLHIQNECKKLGYQLIEIYIDGGVSGNDGNRFALNRLLEDAKFKTFNCVMFTKPDR
LSRNLGYSINVVKSLEQLQVKIHCIEQPIINKPGLMFNILGSFAEHERDMIKERTDSGRKAKWKSESSVIGSLPFGYKKV
NGKVEIDDLNSLIYNRIVNMYLNQNYSMKDIAVKLTAEGIPLPGASNNKHSNSWSSTTISDILKNDSYTGITYQNKYVFE
SRKSKKTNKSYYAATNVEKDKSEWIKRTYPKLIDQDRFDKIQKRISLQKKKPKKQHSGLNEHFMADNTLYCGYCGTRLRK
LKTNEGKLKYTCHWAYTTKTDLFLSNRNKCILKPIDAKEADDRIFDEITEIISDPGHFAQEWLRDTNIDELSDKVNRLNK
IENNLRNALLDGFRLVQESDNPEIKQIYKDALRNKEQEFSEVQNSLKNANNELFFAVNKVNHLAEFQSALEDAAKRDKIG
IYFSAKAQFKTFLCNLPFQEKKRIVGAVVSPEDGGKYLVRHPTLNDIADDTDSIPEDELYTSLPAKGHILDGIFSIDLNR
IQSIISSLNYMELLSSAVPG

Sequences:

>Translated_580_residues
MKVVGYCRVSTQEQAVNGTSIETQKLHIQNECKKLGYQLIEIYIDGGVSGNDGNRFALNRLLEDAKFKTFNCVMFTKPDR
LSRNLGYSINVVKSLEQLQVKIHCIEQPIINKPGLMFNILGSFAEHERDMIKERTDSGRKAKWKSESSVIGSLPFGYKKV
NGKVEIDDLNSLIYNRIVNMYLNQNYSMKDIAVKLTAEGIPLPGASNNKHSNSWSSTTISDILKNDSYTGITYQNKYVFE
SRKSKKTNKSYYAATNVEKDKSEWIKRTYPKLIDQDRFDKIQKRISLQKKKPKKQHSGLNEHFMADNTLYCGYCGTRLRK
LKTNEGKLKYTCHWAYTTKTDLFLSNRNKCILKPIDAKEADDRIFDEITEIISDPGHFAQEWLRDTNIDELSDKVNRLNK
IENNLRNALLDGFRLVQESDNPEIKQIYKDALRNKEQEFSEVQNSLKNANNELFFAVNKVNHLAEFQSALEDAAKRDKIG
IYFSAKAQFKTFLCNLPFQEKKRIVGAVVSPEDGGKYLVRHPTLNDIADDTDSIPEDELYTSLPAKGHILDGIFSIDLNR
IQSIISSLNYMELLSSAVPG
>Mature_580_residues
MKVVGYCRVSTQEQAVNGTSIETQKLHIQNECKKLGYQLIEIYIDGGVSGNDGNRFALNRLLEDAKFKTFNCVMFTKPDR
LSRNLGYSINVVKSLEQLQVKIHCIEQPIINKPGLMFNILGSFAEHERDMIKERTDSGRKAKWKSESSVIGSLPFGYKKV
NGKVEIDDLNSLIYNRIVNMYLNQNYSMKDIAVKLTAEGIPLPGASNNKHSNSWSSTTISDILKNDSYTGITYQNKYVFE
SRKSKKTNKSYYAATNVEKDKSEWIKRTYPKLIDQDRFDKIQKRISLQKKKPKKQHSGLNEHFMADNTLYCGYCGTRLRK
LKTNEGKLKYTCHWAYTTKTDLFLSNRNKCILKPIDAKEADDRIFDEITEIISDPGHFAQEWLRDTNIDELSDKVNRLNK
IENNLRNALLDGFRLVQESDNPEIKQIYKDALRNKEQEFSEVQNSLKNANNELFFAVNKVNHLAEFQSALEDAAKRDKIG
IYFSAKAQFKTFLCNLPFQEKKRIVGAVVSPEDGGKYLVRHPTLNDIADDTDSIPEDELYTSLPAKGHILDGIFSIDLNR
IQSIISSLNYMELLSSAVPG

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 66324; Mature: 66324

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00397 RECOMBINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVGYCRVSTQEQAVNGTSIETQKLHIQNECKKLGYQLIEIYIDGGVSGNDGNRFALNR
CCEEEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHH
LLEDAKFKTFNCVMFTKPDRLSRNLGYSINVVKSLEQLQVKIHCIEQPIINKPGLMFNIL
HHHHCCCCEEEEEEEECCHHHHHCCCCEEHHHHHHHHHHHHHEEECCCCCCCCCHHHHHH
GSFAEHERDMIKERTDSGRKAKWKSESSVIGSLPFGYKKVNGKVEIDDLNSLIYNRIVNM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEECCCEEEEHHHHHHHHHHHHHH
YLNQNYSMKDIAVKLTAEGIPLPGASNNKHSNSWSSTTISDILKNDSYTGITYQNKYVFE
HHCCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEECCCEEEC
SRKSKKTNKSYYAATNVEKDKSEWIKRTYPKLIDQDRFDKIQKRISLQKKKPKKQHSGLN
CHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHCCCC
EHFMADNTLYCGYCGTRLRKLKTNEGKLKYTCHWAYTTKTDLFLSNRNKCILKPIDAKEA
HHCCCCCCEEEECHHHHHHHHCCCCCCEEEEEEEEEECCEEEEEECCCEEEEECCCCCCC
DDRIFDEITEIISDPGHFAQEWLRDTNIDELSDKVNRLNKIENNLRNALLDGFRLVQESD
HHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPEIKQIYKDALRNKEQEFSEVQNSLKNANNELFFAVNKVNHLAEFQSALEDAAKRDKIG
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCEE
IYFSAKAQFKTFLCNLPFQEKKRIVGAVVSPEDGGKYLVRHPTLNDIADDTDSIPEDELY
EEEECCHHHHHHHCCCCHHHHHHHHEEEECCCCCCEEEEECCCHHHHCCCCCCCCCHHHH
TSLPAKGHILDGIFSIDLNRIQSIISSLNYMELLSSAVPG
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVVGYCRVSTQEQAVNGTSIETQKLHIQNECKKLGYQLIEIYIDGGVSGNDGNRFALNR
CCEEEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHH
LLEDAKFKTFNCVMFTKPDRLSRNLGYSINVVKSLEQLQVKIHCIEQPIINKPGLMFNIL
HHHHCCCCEEEEEEEECCHHHHHCCCCEEHHHHHHHHHHHHHEEECCCCCCCCCHHHHHH
GSFAEHERDMIKERTDSGRKAKWKSESSVIGSLPFGYKKVNGKVEIDDLNSLIYNRIVNM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEECCCEEEEHHHHHHHHHHHHHH
YLNQNYSMKDIAVKLTAEGIPLPGASNNKHSNSWSSTTISDILKNDSYTGITYQNKYVFE
HHCCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEECCCEEEC
SRKSKKTNKSYYAATNVEKDKSEWIKRTYPKLIDQDRFDKIQKRISLQKKKPKKQHSGLN
CHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHCCCC
EHFMADNTLYCGYCGTRLRKLKTNEGKLKYTCHWAYTTKTDLFLSNRNKCILKPIDAKEA
HHCCCCCCEEEECHHHHHHHHCCCCCCEEEEEEEEEECCEEEEEECCCEEEEECCCCCCC
DDRIFDEITEIISDPGHFAQEWLRDTNIDELSDKVNRLNKIENNLRNALLDGFRLVQESD
HHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPEIKQIYKDALRNKEQEFSEVQNSLKNANNELFFAVNKVNHLAEFQSALEDAAKRDKIG
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCEE
IYFSAKAQFKTFLCNLPFQEKKRIVGAVVSPEDGGKYLVRHPTLNDIADDTDSIPEDELY
EEEECCHHHHHHHCCCCHHHHHHHHEEEECCCCCCEEEEECCCHHHHCCCCCCCCCHHHH
TSLPAKGHILDGIFSIDLNRIQSIISSLNYMELLSSAVPG
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]