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The map label for this gene is glmS [H]

Identifier: 118578541

GI number: 118578541

Start: 109621

End: 111450

Strand: Direct

Name: glmS [H]

Synonym: Ppro_0093

Alternate gene names: 118578541

Gene position: 109621-111450 (Clockwise)

Preceding gene: 118578540

Following gene: 118578543

Centisome position: 2.74

GC content: 64.75

Gene sequence:

>1830_bases
ATGTGCGGTATCGTAGGATATATCGGCGGCCAGGCCGCCACCCCCATCATTCTGGAGGGGCTGAAAAAACTGGAGTACCG
GGGGTACGACTCGGCCGGCATCGCCACCCTGGCGGACGGCGGCTCCGCCATCCGCCGCAGCGAGGGGAAGCTGGTCAACC
TGGAGAACCTGCTGGCCGAGCAGCCGCTTTTGGGCTCCATCGGCATCGGCCACACCCGTTGGGCCACCCACGGCCGCCCT
TCCGAGATCAACGCCCATCCCCACAGGGCCGGCTCCATCATCGTGGTGCACAACGGCATTATCGAGAACTACCTGCAGCT
GCGCGAGGAGCTCAAAAAAGGGGGCCATACGTTCAGGAGCGAGACCGACACAGAGGTCATCTCCCACCTGATCGAGGATA
CCCTCACCCGGGAGCCGGATTTCGAGAAGGCCGTGAGAACGGCTCTCTCCCGCCTGGTGGGGGCCTATGCGGTCTGCATC
TTGAACGAGTGGGAGCCGGGAACGCTGATCGCCGCCAAGCTCGGTTCTCCCCTGGTGGTGGGGCTGGGCACGGGTGAATT
CTTCGTCGCCTCCGATATCCCCGCCATCCTGGCCCACACCCGCGAGATGGTCTTCATGGATGACGGCGAGATGGCCGTGT
TCCGTGACGGGTCGGCCTCCTTCTCCACCATCCAAGGCTCCCCCCTGGACAAGAAGGCGCGCCACATCGACTGGTCGCCG
CTGATGGCCGAGAAAGGGGGCTACCGGCACTTCATGCTCAAGGAGATCCACGAGCAGCCCCGGGCCGTGCGCGACACCAT
CGCCGGCCGGTTGCTGGAGGATAGCGGCGACGTGCACCTGGGGGACCTGAATTTCAACGACCAGCAGCTGAGCCGGATCA
GGCGCATCGTCATCGTGGCCTGCGGTACCTCCTGGCACGCGGCGCTCCTGGGCAAGTTCTACCTGGAGGGGCGCTGCCGC
ATCCCGGTGGAGGTGGATATCGCCTCCGAGTTCCGCTACCGCGATCCGGTGATCGATGGTTCCACCCTGATGATGGTCAT
CTCCCAGTCCGGCGAGACCGCCGATACCCTGGCTGCCCTGCGCGAGGCCAAGTCCCGGGGCGCCATGGCCATGGCCATCT
GCAACGTGGTGGACTCCTCCATCGCCCGCGAGGCGGGCAACGTGATCTACACCCATGCCGGCCCGGAGATCGGCGTGGCC
TCCACCAAGGCCTTCGTCACCCAGCTGACGGCCCTGTACCTGTTCACCATCCGTCTGGGCCGCAGCATTGGTAGTATCGA
CGCCGAAACCGGAAAGGCGATGCTGGCCTCCCTCAAGCGGGTGCCATCCCTGCTGGAAGAGGTGCTCAAGCTGAACGGGT
GCACCGAGAAGATCGCCCGCAAGTACATGAACGCCCGTGACTTCCTCTACCTGGGGCGTGGCAAGAACTACCCCATCGCC
CTGGAGGGGGCGCTCAAGCTGAAGGAGATCTCCTACATCCATGCCGAGGGATACCCGGCAGGCGAGATGAAGCACGGCCC
CATCGCCCTGATCGACGAGGATATGCCGGTGGTGGTGCTGGCGCCGCGCAACAGTGCCTTCGAGAAGACCCTCTCCAACA
TGGAGGAGGTGATTGCCCGCAGCGGTCGGGTGATCGCGCTCTGCAGCGCCGGTGATGATGAGGTGAGCGGGAGGGCCGAG
GATGTCATCCAGATTCCCCGTCTGGACGAGGACATGGACCCGCTGCTGCTCTCCGTGCCGCTGCAGCTTCTGGCCTACCA
TGTGGCGGTGCTCAAGGGTACCGACGTTGACCAGCCGCGCAACCTGGCCAAATCGGTGACGGTTGAGTAG

Upstream 100 bases:

>100_bases
GGGAGGGACCCGTTCCCCCGTTGCCGCCCACGCTTCTCCTCCCTGGGAGGGAGGATTTCACGGCAGGGCTTTCCCTGCCA
TTTCCGGAGGAATACAGATT

Downstream 100 bases:

>100_bases
GCCGGGAGGAATCGTTGGTGCTGGTGATTCGCCACAATAACGTGGAAACTGAAATGGCTGCCGGAGTATTGGCAGCCATT
TTCCGTGTGGCACCGCCTAT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MCGIVGYIGGQAATPIILEGLKKLEYRGYDSAGIATLADGGSAIRRSEGKLVNLENLLAEQPLLGSIGIGHTRWATHGRP
SEINAHPHRAGSIIVVHNGIIENYLQLREELKKGGHTFRSETDTEVISHLIEDTLTREPDFEKAVRTALSRLVGAYAVCI
LNEWEPGTLIAAKLGSPLVVGLGTGEFFVASDIPAILAHTREMVFMDDGEMAVFRDGSASFSTIQGSPLDKKARHIDWSP
LMAEKGGYRHFMLKEIHEQPRAVRDTIAGRLLEDSGDVHLGDLNFNDQQLSRIRRIVIVACGTSWHAALLGKFYLEGRCR
IPVEVDIASEFRYRDPVIDGSTLMMVISQSGETADTLAALREAKSRGAMAMAICNVVDSSIAREAGNVIYTHAGPEIGVA
STKAFVTQLTALYLFTIRLGRSIGSIDAETGKAMLASLKRVPSLLEEVLKLNGCTEKIARKYMNARDFLYLGRGKNYPIA
LEGALKLKEISYIHAEGYPAGEMKHGPIALIDEDMPVVVLAPRNSAFEKTLSNMEEVIARSGRVIALCSAGDDEVSGRAE
DVIQIPRLDEDMDPLLLSVPLQLLAYHVAVLKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_609_residues
MCGIVGYIGGQAATPIILEGLKKLEYRGYDSAGIATLADGGSAIRRSEGKLVNLENLLAEQPLLGSIGIGHTRWATHGRP
SEINAHPHRAGSIIVVHNGIIENYLQLREELKKGGHTFRSETDTEVISHLIEDTLTREPDFEKAVRTALSRLVGAYAVCI
LNEWEPGTLIAAKLGSPLVVGLGTGEFFVASDIPAILAHTREMVFMDDGEMAVFRDGSASFSTIQGSPLDKKARHIDWSP
LMAEKGGYRHFMLKEIHEQPRAVRDTIAGRLLEDSGDVHLGDLNFNDQQLSRIRRIVIVACGTSWHAALLGKFYLEGRCR
IPVEVDIASEFRYRDPVIDGSTLMMVISQSGETADTLAALREAKSRGAMAMAICNVVDSSIAREAGNVIYTHAGPEIGVA
STKAFVTQLTALYLFTIRLGRSIGSIDAETGKAMLASLKRVPSLLEEVLKLNGCTEKIARKYMNARDFLYLGRGKNYPIA
LEGALKLKEISYIHAEGYPAGEMKHGPIALIDEDMPVVVLAPRNSAFEKTLSNMEEVIARSGRVIALCSAGDDEVSGRAE
DVIQIPRLDEDMDPLLLSVPLQLLAYHVAVLKGTDVDQPRNLAKSVTVE
>Mature_609_residues
MCGIVGYIGGQAATPIILEGLKKLEYRGYDSAGIATLADGGSAIRRSEGKLVNLENLLAEQPLLGSIGIGHTRWATHGRP
SEINAHPHRAGSIIVVHNGIIENYLQLREELKKGGHTFRSETDTEVISHLIEDTLTREPDFEKAVRTALSRLVGAYAVCI
LNEWEPGTLIAAKLGSPLVVGLGTGEFFVASDIPAILAHTREMVFMDDGEMAVFRDGSASFSTIQGSPLDKKARHIDWSP
LMAEKGGYRHFMLKEIHEQPRAVRDTIAGRLLEDSGDVHLGDLNFNDQQLSRIRRIVIVACGTSWHAALLGKFYLEGRCR
IPVEVDIASEFRYRDPVIDGSTLMMVISQSGETADTLAALREAKSRGAMAMAICNVVDSSIAREAGNVIYTHAGPEIGVA
STKAFVTQLTALYLFTIRLGRSIGSIDAETGKAMLASLKRVPSLLEEVLKLNGCTEKIARKYMNARDFLYLGRGKNYPIA
LEGALKLKEISYIHAEGYPAGEMKHGPIALIDEDMPVVVLAPRNSAFEKTLSNMEEVIARSGRVIALCSAGDDEVSGRAE
DVIQIPRLDEDMDPLLLSVPLQLLAYHVAVLKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=37.956204379562, Blast_Score=450, Evalue=1e-126,
Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=36.6959064327485, Blast_Score=440, Evalue=1e-123,
Organism=Homo sapiens, GI29570798, Length=180, Percent_Identity=32.2222222222222, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790167, Length=612, Percent_Identity=50, Blast_Score=576, Evalue=1e-165,
Organism=Escherichia coli, GI1788651, Length=173, Percent_Identity=33.5260115606936, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17539970, Length=430, Percent_Identity=41.1627906976744, Blast_Score=320, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17532899, Length=438, Percent_Identity=39.9543378995434, Blast_Score=317, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI17532897, Length=438, Percent_Identity=39.9543378995434, Blast_Score=317, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6322745, Length=444, Percent_Identity=39.1891891891892, Blast_Score=307, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6323731, Length=438, Percent_Identity=30.5936073059361, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6323730, Length=206, Percent_Identity=37.378640776699, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6323958, Length=169, Percent_Identity=27.810650887574, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI21357745, Length=685, Percent_Identity=38.8321167883212, Blast_Score=465, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66286; Mature: 66286

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYIGGQAATPIILEGLKKLEYRGYDSAGIATLADGGSAIRRSEGKLVNLENLLAE
CCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHCCCCCEECHHHHHHC
QPLLGSIGIGHTRWATHGRPSEINAHPHRAGSIIVVHNGIIENYLQLREELKKGGHTFRS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCC
ETDTEVISHLIEDTLTREPDFEKAVRTALSRLVGAYAVCILNEWEPGTLIAAKLGSPLVV
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCCCEEE
GLGTGEFFVASDIPAILAHTREMVFMDDGEMAVFRDGSASFSTIQGSPLDKKARHIDWSP
EECCCCEEEECCCHHHHHCCCEEEEEECCCEEEEECCCCCCCEECCCCCCCHHHCCCCCC
LMAEKGGYRHFMLKEIHEQPRAVRDTIAGRLLEDSGDVHLGDLNFNDQQLSRIRRIVIVA
HHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCEEEEEE
CGTSWHAALLGKFYLEGRCRIPVEVDIASEFRYRDPVIDGSTLMMVISQSGETADTLAAL
ECCCHHHHHHHHHHCCCCEECCEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHH
REAKSRGAMAMAICNVVDSSIAREAGNVIYTHAGPEIGVASTKAFVTQLTALYLFTIRLG
HHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHC
RSIGSIDAETGKAMLASLKRVPSLLEEVLKLNGCTEKIARKYMNARDFLYLGRGKNYPIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCEE
LEGALKLKEISYIHAEGYPAGEMKHGPIALIDEDMPVVVLAPRNSAFEKTLSNMEEVIAR
EECCEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHC
SGRVIALCSAGDDEVSGRAEDVIQIPRLDEDMDPLLLSVPLQLLAYHVAVLKGTDVDQPR
CCCEEEEECCCCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
NLAKSVTVE
HHHHHCCCC
>Mature Secondary Structure
MCGIVGYIGGQAATPIILEGLKKLEYRGYDSAGIATLADGGSAIRRSEGKLVNLENLLAE
CCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHCCCCCEECHHHHHHC
QPLLGSIGIGHTRWATHGRPSEINAHPHRAGSIIVVHNGIIENYLQLREELKKGGHTFRS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCC
ETDTEVISHLIEDTLTREPDFEKAVRTALSRLVGAYAVCILNEWEPGTLIAAKLGSPLVV
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCCCEEE
GLGTGEFFVASDIPAILAHTREMVFMDDGEMAVFRDGSASFSTIQGSPLDKKARHIDWSP
EECCCCEEEECCCHHHHHCCCEEEEEECCCEEEEECCCCCCCEECCCCCCCHHHCCCCCC
LMAEKGGYRHFMLKEIHEQPRAVRDTIAGRLLEDSGDVHLGDLNFNDQQLSRIRRIVIVA
HHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCEEEEEE
CGTSWHAALLGKFYLEGRCRIPVEVDIASEFRYRDPVIDGSTLMMVISQSGETADTLAAL
ECCCHHHHHHHHHHCCCCEECCEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHH
REAKSRGAMAMAICNVVDSSIAREAGNVIYTHAGPEIGVASTKAFVTQLTALYLFTIRLG
HHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHC
RSIGSIDAETGKAMLASLKRVPSLLEEVLKLNGCTEKIARKYMNARDFLYLGRGKNYPIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCEE
LEGALKLKEISYIHAEGYPAGEMKHGPIALIDEDMPVVVLAPRNSAFEKTLSNMEEVIAR
EECCEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHC
SGRVIALCSAGDDEVSGRAEDVIQIPRLDEDMDPLLLSVPLQLLAYHVAVLKGTDVDQPR
CCCEEEEECCCCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
NLAKSVTVE
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA