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The map label for this gene is pbpG [H]

Identifier: 118578528

GI number: 118578528

Start: 92125

End: 94239

Strand: Direct

Name: pbpG [H]

Synonym: Ppro_0080

Alternate gene names: 118578528

Gene position: 92125-94239 (Clockwise)

Preceding gene: 118578527

Following gene: 118578529

Centisome position: 2.3

GC content: 64.78

Gene sequence:

>2115_bases
ATGTATCCTGGAAACGGCATTGGGGAGCTGCCGCGCGTTCGCGCGGACGGGCTCTCTCCGGCAGCTCCCACATGCCAATG
TACGTTTATCACCCACAAGGAGTACACGATCACCGTGATTTTCACCCCATCCCTCTCTGCAAGAAAATGGATCTGCTTCA
TCCTGCTGTGCAGTTTCCTCCTCATTCCCGCCGCCCCGCTCCTGGCCCGGGAGAGCTTCGCCAGCCACCCCACGTTGCCG
CGGGGCTACAGCTCCATCAGGATCTTCGACAACCAGGGGCGCTTCGTTGGCCGTATCCTCCCGGAGCGGAGGTACTGGGT
CTCCATCGACCGCATCCCCAGCTTCCTGCAGAAGGCGGTCATCGCCGTGGAGGACGCCCGCTTCTACGAGCATAGCGGCA
TCGATGTGCGCGGTATCGCCCGGGCCCTGGTGAAGGATGTGGTCAAGGGAAGAATGGCCGAGGGGGGCTCCACCATCACC
CAGCAGCTGATCAAGAATCGGTACCTGTCCGGGGAGAAGACCATCGACAGGAAACTGAAGGAAGGGCGCATGGCCCTGGA
GTTCGAGCAGAAGTACACGAAGAAGCAGATCCTGGAGATGTACTTCAACGAGATCTACTACGGGAATGGGGCCTGGGGAA
TCGCCCAGGCCGCCCGCCTCTACTTCGACAAGAACCCCGAGCAGCTGAGCGAGGCCGAATGCTCGCTTTTGGCCGGGGTG
CCCAAGGCGCCGGGCGTCTACAATCCGCGGGGAAAGGCGTCCAATGTCATGGCGCGCAGGGATGTCGTTCTCAAGCGCAT
GGTGGAGCTGGGTATGATCTCCCGCGGCAAACAGCAGAGCCTGCGGGTCCATCCCCCCTCGGTCATTCCTCCCGGCCCGG
CTCCCTCCTATGTGGCCCATATCCGGAGCAGGCTGATTGAGCAGTACGGTGCGGGGATCGTCGAGCAGGGGGGGCTGGAG
GTGACCACGGCCATGGACCTGAAACTCCAGAAGCTGGCGGAGAAGACTCTTGGCGAGGGGGTCAGGCGCGTATCGCCACA
ACTCCAGGGCGCGCTGGTCTGCCTGGACCCGGCCAACGGCGACCTGCTGGCCATGGTGGGGGGCACAGGCTCCGACGGGA
ACGGCTACAACCGCGCCTTGTCGGCCAGGCGTCAGCCCGGGTCGGCCATCAAGCCGCTGATCTTTGCCGCGGCGGTGGAA
AATGGCTATACGGCCGCCAGCATCTGGAACGACCGGCCGGAGAGCTACAGCAGCGGCAGTGCCGGAACCTGGAAACCGCG
CAACTACGGCGGAGAGCGCTTCGGAGACCTGTCGCTCAGGCAGGCCCTGGCCTACTCCAACAACGTCATCACGGTGAAGC
TGCTGGATGCGGTGGGCGTCCCCGCTTTTACCGATTTCGCTGCCCGCCTGGGGCTTCCCCTGCGGGCGCGACACGATCTG
ACCCTGGCCCTGGGAACCGAAGAGGTCACCCTGCACGATCTGGTGCTTGCCTACGCCCCCCTGGCAAATGGTGGCTCGCG
GCCCAAGTCGCGCAGCATCATCCGCATCTACGACCGCAGGCACGAGAGCTGGACGAACAATCCCCCGGCACTGACGCCGG
TCCTCTCCCCGGCAAGCGCCTATGTCACCACCCAGATGATGAGGGATGTCATGGTCTACGGCACCGCCAAGAGCCTGAAG
AAGTTCAGCTTGAAACGTCCCTCGGCCGGGAAGACCGGCACCACCGACGACTACCGGGATGCCTGGTTCGTGGGCTATAC
CCCACAGATCATAACCGGCATCTGGGTGGGGCATGACAAGCCGCGGCCCGGCGGGAAGGGCTTTACCGGCGGTGCGGTCC
CCGCGCCCATCTGGGGGCGATTCATGGATCAGGCGCTGGCCTCCCGGCCGGCGGTCGACTTCACCCGGCCGGATACGGTG
GTTTCCGTAACCATCGATCCCGCCACCGGCTTTCTGGCGACGCCGGACTGCCCGCGGAAACGGGTCGAGTTCTTTGTCCA
GGGGACCGAGCCGATGGAGAGCTGTCCCGAGCATGGCGGAAGCGTTGCTGCGCCAGCGTCCGTACCCCCCGTGGCTCCGG
CGAGCGACGGCCAGCAGCCGGTCCAGCAGCCCTGA

Upstream 100 bases:

>100_bases
GTCAGGCGCTGGTACGGTACGGAGCAATGAATCAGAGGCTCACATCTGTTTCCGAATCCAGAACAACGCGGATCAGGTGT
GTGCCTGAGATGCCTGTCGC

Downstream 100 bases:

>100_bases
GGGACGAAATCACACCAGCAAGGAGATTCTGTTGAGCTTCACTGTACGTAATCCTGAGTATGAGGCGCGCATACGGGAGA
GGTTTGCCACCACCGGAACC

Product: 1A family penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MYPGNGIGELPRVRADGLSPAAPTCQCTFITHKEYTITVIFTPSLSARKWICFILLCSFLLIPAAPLLARESFASHPTLP
RGYSSIRIFDNQGRFVGRILPERRYWVSIDRIPSFLQKAVIAVEDARFYEHSGIDVRGIARALVKDVVKGRMAEGGSTIT
QQLIKNRYLSGEKTIDRKLKEGRMALEFEQKYTKKQILEMYFNEIYYGNGAWGIAQAARLYFDKNPEQLSEAECSLLAGV
PKAPGVYNPRGKASNVMARRDVVLKRMVELGMISRGKQQSLRVHPPSVIPPGPAPSYVAHIRSRLIEQYGAGIVEQGGLE
VTTAMDLKLQKLAEKTLGEGVRRVSPQLQGALVCLDPANGDLLAMVGGTGSDGNGYNRALSARRQPGSAIKPLIFAAAVE
NGYTAASIWNDRPESYSSGSAGTWKPRNYGGERFGDLSLRQALAYSNNVITVKLLDAVGVPAFTDFAARLGLPLRARHDL
TLALGTEEVTLHDLVLAYAPLANGGSRPKSRSIIRIYDRRHESWTNNPPALTPVLSPASAYVTTQMMRDVMVYGTAKSLK
KFSLKRPSAGKTGTTDDYRDAWFVGYTPQIITGIWVGHDKPRPGGKGFTGGAVPAPIWGRFMDQALASRPAVDFTRPDTV
VSVTIDPATGFLATPDCPRKRVEFFVQGTEPMESCPEHGGSVAAPASVPPVAPASDGQQPVQQP

Sequences:

>Translated_704_residues
MYPGNGIGELPRVRADGLSPAAPTCQCTFITHKEYTITVIFTPSLSARKWICFILLCSFLLIPAAPLLARESFASHPTLP
RGYSSIRIFDNQGRFVGRILPERRYWVSIDRIPSFLQKAVIAVEDARFYEHSGIDVRGIARALVKDVVKGRMAEGGSTIT
QQLIKNRYLSGEKTIDRKLKEGRMALEFEQKYTKKQILEMYFNEIYYGNGAWGIAQAARLYFDKNPEQLSEAECSLLAGV
PKAPGVYNPRGKASNVMARRDVVLKRMVELGMISRGKQQSLRVHPPSVIPPGPAPSYVAHIRSRLIEQYGAGIVEQGGLE
VTTAMDLKLQKLAEKTLGEGVRRVSPQLQGALVCLDPANGDLLAMVGGTGSDGNGYNRALSARRQPGSAIKPLIFAAAVE
NGYTAASIWNDRPESYSSGSAGTWKPRNYGGERFGDLSLRQALAYSNNVITVKLLDAVGVPAFTDFAARLGLPLRARHDL
TLALGTEEVTLHDLVLAYAPLANGGSRPKSRSIIRIYDRRHESWTNNPPALTPVLSPASAYVTTQMMRDVMVYGTAKSLK
KFSLKRPSAGKTGTTDDYRDAWFVGYTPQIITGIWVGHDKPRPGGKGFTGGAVPAPIWGRFMDQALASRPAVDFTRPDTV
VSVTIDPATGFLATPDCPRKRVEFFVQGTEPMESCPEHGGSVAAPASVPPVAPASDGQQPVQQP
>Mature_704_residues
MYPGNGIGELPRVRADGLSPAAPTCQCTFITHKEYTITVIFTPSLSARKWICFILLCSFLLIPAAPLLARESFASHPTLP
RGYSSIRIFDNQGRFVGRILPERRYWVSIDRIPSFLQKAVIAVEDARFYEHSGIDVRGIARALVKDVVKGRMAEGGSTIT
QQLIKNRYLSGEKTIDRKLKEGRMALEFEQKYTKKQILEMYFNEIYYGNGAWGIAQAARLYFDKNPEQLSEAECSLLAGV
PKAPGVYNPRGKASNVMARRDVVLKRMVELGMISRGKQQSLRVHPPSVIPPGPAPSYVAHIRSRLIEQYGAGIVEQGGLE
VTTAMDLKLQKLAEKTLGEGVRRVSPQLQGALVCLDPANGDLLAMVGGTGSDGNGYNRALSARRQPGSAIKPLIFAAAVE
NGYTAASIWNDRPESYSSGSAGTWKPRNYGGERFGDLSLRQALAYSNNVITVKLLDAVGVPAFTDFAARLGLPLRARHDL
TLALGTEEVTLHDLVLAYAPLANGGSRPKSRSIIRIYDRRHESWTNNPPALTPVLSPASAYVTTQMMRDVMVYGTAKSLK
KFSLKRPSAGKTGTTDDYRDAWFVGYTPQIITGIWVGHDKPRPGGKGFTGGAVPAPIWGRFMDQALASRPAVDFTRPDTV
VSVTIDPATGFLATPDCPRKRVEFFVQGTEPMESCPEHGGSVAAPASVPPVAPASDGQQPVQQP

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=572, Percent_Identity=30.9440559440559, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1788867, Length=590, Percent_Identity=29.3220338983051, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87082258, Length=263, Percent_Identity=37.6425855513308, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1789601, Length=166, Percent_Identity=36.7469879518072, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 76716; Mature: 76716

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPGNGIGELPRVRADGLSPAAPTCQCTFITHKEYTITVIFTPSLSARKWICFILLCSFL
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHH
LIPAAPLLARESFASHPTLPRGYSSIRIFDNQGRFVGRILPERRYWVSIDRIPSFLQKAV
HHCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHHHHHHHHHH
IAVEDARFYEHSGIDVRGIARALVKDVVKGRMAEGGSTITQQLIKNRYLSGEKTIDRKLK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH
EGRMALEFEQKYTKKQILEMYFNEIYYGNGAWGIAQAARLYFDKNPEQLSEAECSLLAGV
HCCEEEHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
PKAPGVYNPRGKASNVMARRDVVLKRMVELGMISRGKQQSLRVHPPSVIPPGPAPSYVAH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHH
IRSRLIEQYGAGIVEQGGLEVTTAMDLKLQKLAEKTLGEGVRRVSPQLQGALVCLDPANG
HHHHHHHHHCCCCEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHCCEEEEEECCCC
DLLAMVGGTGSDGNGYNRALSARRQPGSAIKPLIFAAAVENGYTAASIWNDRPESYSSGS
CEEEEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
AGTWKPRNYGGERFGDLSLRQALAYSNNVITVKLLDAVGVPAFTDFAARLGLPLRARHDL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCEECCCCE
TLALGTEEVTLHDLVLAYAPLANGGSRPKSRSIIRIYDRRHESWTNNPPALTPVLSPASA
EEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCHHH
YVTTQMMRDVMVYGTAKSLKKFSLKRPSAGKTGTTDDYRDAWFVGYTPQIITGIWVGHDK
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCHHHHEEEEECCCC
PRPGGKGFTGGAVPAPIWGRFMDQALASRPAVDFTRPDTVVSVTIDPATGFLATPDCPRK
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHH
RVEFFVQGTEPMESCPEHGGSVAAPASVPPVAPASDGQQPVQQP
HHHEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYPGNGIGELPRVRADGLSPAAPTCQCTFITHKEYTITVIFTPSLSARKWICFILLCSFL
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHH
LIPAAPLLARESFASHPTLPRGYSSIRIFDNQGRFVGRILPERRYWVSIDRIPSFLQKAV
HHCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHHHHHHHHHH
IAVEDARFYEHSGIDVRGIARALVKDVVKGRMAEGGSTITQQLIKNRYLSGEKTIDRKLK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH
EGRMALEFEQKYTKKQILEMYFNEIYYGNGAWGIAQAARLYFDKNPEQLSEAECSLLAGV
HCCEEEHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
PKAPGVYNPRGKASNVMARRDVVLKRMVELGMISRGKQQSLRVHPPSVIPPGPAPSYVAH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHH
IRSRLIEQYGAGIVEQGGLEVTTAMDLKLQKLAEKTLGEGVRRVSPQLQGALVCLDPANG
HHHHHHHHHCCCCEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHCCEEEEEECCCC
DLLAMVGGTGSDGNGYNRALSARRQPGSAIKPLIFAAAVENGYTAASIWNDRPESYSSGS
CEEEEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
AGTWKPRNYGGERFGDLSLRQALAYSNNVITVKLLDAVGVPAFTDFAARLGLPLRARHDL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCEECCCCE
TLALGTEEVTLHDLVLAYAPLANGGSRPKSRSIIRIYDRRHESWTNNPPALTPVLSPASA
EEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCHHH
YVTTQMMRDVMVYGTAKSLKKFSLKRPSAGKTGTTDDYRDAWFVGYTPQIITGIWVGHDK
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCHHHHEEEEECCCC
PRPGGKGFTGGAVPAPIWGRFMDQALASRPAVDFTRPDTVVSVTIDPATGFLATPDCPRK
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHH
RVEFFVQGTEPMESCPEHGGSVAAPASVPPVAPASDGQQPVQQP
HHHEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]