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The map label for this gene is gpsA [H]

Identifier: 118578456

GI number: 118578456

Start: 10401

End: 11420

Strand: Direct

Name: gpsA [H]

Synonym: Ppro_0007

Alternate gene names: 118578456

Gene position: 10401-11420 (Clockwise)

Preceding gene: 118578455

Following gene: 118578457

Centisome position: 0.26

GC content: 65.59

Gene sequence:

>1020_bases
ATGACGACGAAGAATAGCCCGCTCAGGGTGGCGGTCATCGGCGGCGGAAGCTGGGGTACGGCCCTGGCCAACGTGCTGGC
GGGGAATAGCCATGACACGGTTCTCTGGGTGCATGACACCGAGCTGGTGGACGAGATCAACCAGCGCCACATGAACCCGC
TCTTCCTCCCCGGCATCCCGCTCTGCCCCGCTTTGGTCTGCACAGAGAACCTGACCCACGCCCTGTCCGGTCGCGATCTT
GTCCTGATGGTGACGCCGGTGCAGGTCATGCGCGGCGTCCTGGACCGGGCCCGGGGGCTGATCGACCCGGATGCCGTGAT
CGTCAACGCCTCCAAGGGGATCGAGCTGGAGAGCCTGAAGACCGTGTCCCAGATCTGCGCCGAGTTTTTCGGAGAGCGGT
TCCTGGAGCGCTATGTGGCCCTGTCCGGCCCCACCTTTGCCCGCGAGGTCGCTCAGGGACTCCCCTCCTTGATCGTGGCC
GCCTCCCGCGTTGAATCCTGTGCCCGAAAGGTGCAGACCGCCTTCAGCAATCCAACATTCCGCGCCTACACCAACAGCGA
CGTTATCGGCGTGGAGCTGGGGGGAGCGGTCAAGAACGTGATCGCCATTGCCGCCGGCATCTGCGATGGCCTGGGTTTCG
GCCACAACGCCCGTGCGGCCCTGATCACCCGCGGCTTGGCCGAGATGAACCGTCTGGGGCTGGCCATGGGGGCCCAGGCT
GCCACCTTCGCTGGCCTGGCCGGCATGGGCGACCTGGTGCTGACCTGCACCGGCGATCTCTCCCGCAACCGCACCGTCGG
CTTTAAGCTGGGGCAGGGGATGCGTTTGAAAGACATCCTGGCCGAGATGCGCATGGTGGCCGAGGGGGTCAAGACCGCCG
AATCGGTCTTCCAGCTCTCCCGCAAGCTGGGGGTGGAGATGCCCATCGTGGAGAAGGCCTATCAGATCCTTCACGAGGAC
AAGCCGGCCAAGCAGGCGGTGACGGAACTGATGGCCAGGGCGCTGAAGGCGGAGGGGTAG

Upstream 100 bases:

>100_bases
GAGTCGCGCCACCCCTTTATCAGGCGCTTGATTATGGATAGTATCGAGACGGCCCGCCAGGCCCTGGCCGACGGGTACGA
CCTACGATTGGAGGAAGGCT

Downstream 100 bases:

>100_bases
GGGACGTTATTGTCCATTGTGGATAGCTTGCCGGTCCGTTCCCGATATGAAGGACAATGACCATGGCGAGGGATCGAGGA
AAAGCGCCGGTCACAGTAGC

Product: glycerol-3-phosphate dehydrogenase (NAD(P)(+))

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTTKNSPLRVAVIGGGSWGTALANVLAGNSHDTVLWVHDTELVDEINQRHMNPLFLPGIPLCPALVCTENLTHALSGRDL
VLMVTPVQVMRGVLDRARGLIDPDAVIVNASKGIELESLKTVSQICAEFFGERFLERYVALSGPTFAREVAQGLPSLIVA
ASRVESCARKVQTAFSNPTFRAYTNSDVIGVELGGAVKNVIAIAAGICDGLGFGHNARAALITRGLAEMNRLGLAMGAQA
ATFAGLAGMGDLVLTCTGDLSRNRTVGFKLGQGMRLKDILAEMRMVAEGVKTAESVFQLSRKLGVEMPIVEKAYQILHED
KPAKQAVTELMARALKAEG

Sequences:

>Translated_339_residues
MTTKNSPLRVAVIGGGSWGTALANVLAGNSHDTVLWVHDTELVDEINQRHMNPLFLPGIPLCPALVCTENLTHALSGRDL
VLMVTPVQVMRGVLDRARGLIDPDAVIVNASKGIELESLKTVSQICAEFFGERFLERYVALSGPTFAREVAQGLPSLIVA
ASRVESCARKVQTAFSNPTFRAYTNSDVIGVELGGAVKNVIAIAAGICDGLGFGHNARAALITRGLAEMNRLGLAMGAQA
ATFAGLAGMGDLVLTCTGDLSRNRTVGFKLGQGMRLKDILAEMRMVAEGVKTAESVFQLSRKLGVEMPIVEKAYQILHED
KPAKQAVTELMARALKAEG
>Mature_338_residues
TTKNSPLRVAVIGGGSWGTALANVLAGNSHDTVLWVHDTELVDEINQRHMNPLFLPGIPLCPALVCTENLTHALSGRDLV
LMVTPVQVMRGVLDRARGLIDPDAVIVNASKGIELESLKTVSQICAEFFGERFLERYVALSGPTFAREVAQGLPSLIVAA
SRVESCARKVQTAFSNPTFRAYTNSDVIGVELGGAVKNVIAIAAGICDGLGFGHNARAALITRGLAEMNRLGLAMGAQAA
TFAGLAGMGDLVLTCTGDLSRNRTVGFKLGQGMRLKDILAEMRMVAEGVKTAESVFQLSRKLGVEMPIVEKAYQILHEDK
PAKQAVTELMARALKAEG

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=350, Percent_Identity=30.5714285714286, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI33695088, Length=341, Percent_Identity=28.1524926686217, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1790037, Length=339, Percent_Identity=46.3126843657817, Blast_Score=285, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI32564399, Length=343, Percent_Identity=30.6122448979592, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32564403, Length=352, Percent_Identity=29.8295454545455, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193210136, Length=352, Percent_Identity=29.8295454545455, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17507425, Length=334, Percent_Identity=27.2455089820359, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI193210134, Length=342, Percent_Identity=28.3625730994152, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324513, Length=348, Percent_Identity=30.7471264367816, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6320181, Length=349, Percent_Identity=30.6590257879656, Blast_Score=132, Evalue=6e-32,
Organism=Drosophila melanogaster, GI17136200, Length=332, Percent_Identity=28.3132530120482, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136204, Length=332, Percent_Identity=28.3132530120482, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136202, Length=332, Percent_Identity=28.3132530120482, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI22026922, Length=346, Percent_Identity=26.878612716763, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI45551945, Length=350, Percent_Identity=28, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281362270, Length=239, Percent_Identity=31.7991631799163, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24648969, Length=339, Percent_Identity=27.7286135693215, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36078; Mature: 35947

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKNSPLRVAVIGGGSWGTALANVLAGNSHDTVLWVHDTELVDEINQRHMNPLFLPGIP
CCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCC
LCPALVCTENLTHALSGRDLVLMVTPVQVMRGVLDRARGLIDPDAVIVNASKGIELESLK
HHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHH
TVSQICAEFFGERFLERYVALSGPTFAREVAQGLPSLIVAASRVESCARKVQTAFSNPTF
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCE
RAYTNSDVIGVELGGAVKNVIAIAAGICDGLGFGHNARAALITRGLAEMNRLGLAMGAQA
EEECCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
ATFAGLAGMGDLVLTCTGDLSRNRTVGFKLGQGMRLKDILAEMRMVAEGVKTAESVFQLS
HHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKLGVEMPIVEKAYQILHEDKPAKQAVTELMARALKAEG
HHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTKNSPLRVAVIGGGSWGTALANVLAGNSHDTVLWVHDTELVDEINQRHMNPLFLPGIP
CCCCCCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCC
LCPALVCTENLTHALSGRDLVLMVTPVQVMRGVLDRARGLIDPDAVIVNASKGIELESLK
HHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHH
TVSQICAEFFGERFLERYVALSGPTFAREVAQGLPSLIVAASRVESCARKVQTAFSNPTF
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCE
RAYTNSDVIGVELGGAVKNVIAIAAGICDGLGFGHNARAALITRGLAEMNRLGLAMGAQA
EEECCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
ATFAGLAGMGDLVLTCTGDLSRNRTVGFKLGQGMRLKDILAEMRMVAEGVKTAESVFQLS
HHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKLGVEMPIVEKAYQILHEDKPAKQAVTELMARALKAEG
HHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA