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The map label for this gene is yhcY [H]

Identifier: 118480443

GI number: 118480443

Start: 5174721

End: 5176292

Strand: Reverse

Name: yhcY [H]

Synonym: BALH_4912

Alternate gene names: 118480443

Gene position: 5176292-5174721 (Counterclockwise)

Preceding gene: 118480445

Following gene: 118480442

Centisome position: 98.46

GC content: 35.18

Gene sequence:

>1572_bases
ATGTTTCAAGAGAATCGTACAAATGAATTAGTTATATTAAAAGAAATTGCAGAAACGCTAAATACATCAAATGATACATA
CCATGTATTGCAAGCAGTGCTAGAAAAATTACTTAGTGTAACAGGTTTAACGACAGGATGGATATTTCTTGCGGATGAAA
ATGGTAGATATACAAAATTAATTGATTATCAATTACCAGAGGCACTTACATATGAAAATAAACGCCCGATGTGTGAAGGG
GAATGTTGGTGTTTACGCGGCTTTGTGGATGGAAAGTTAGAGAGAGCTGTTAATATTATTGAATGTAAAAGAATTAATAA
TGCAATTGAATATAATTGGGGAGATACAGAAGGGATTCTTCATCATGCTACGGTTCCTTTAAAGGCTGGAGGAGAAAAAT
TTGGTTTGTTAAATGTGGCAAGCCCAGGTAAAACACATTTTTCAGAAGAAGAATTAGTATTGCTTCAATCAGTTGCTTTC
CAAATTGGAACGGCTTTAAAACGAGCAAAGTTATATGAAAATGAAAAGCGAAGAGCGCATTATTATGTGAAATTAGAACG
TTTCATTCAAGTTTTAAGAACGATTCATCAATTTAATATATTGCCTGAAAAAGTTGTAAATCAATTAGGTGAAGTGTTTC
AGTGGAATCAAGTGGTGTTTTTTATTAGGGAAGAGGAAGAATTATCTTTGAGGGCATCTTATTGCCAGGAAGAATTGCAC
GAGGATATAAAAGAAGCAGCGAAAGAAGCATTAGAAAAAGGTGAACTTATTTTATTAAACGATCAAATCAGTCATAAGGT
AGCCTCTAATAGAACGGTTATTGCCACACCAATACAGATTCAAACTCACATATTTGGTGTTTTATGTGTTAGTTCAAATC
ATGGTGAATTTGATGTAAATACGATAGATGTACTTCAAGCAATAACAAATCATATTTCCTTCGTGATAGAAAATTTAAGG
TTAAATGAGCAACGACGCGAACTTGTACGAATGGAAGAAAGAAATCGGTTAGCAAGGGACTTACATGATTCCGTCTCACA
AAAGCTATTTTCGTTAAACTTTATGACAAAGGGCGCTGAGGCAGTCTTAAAAGGTCAAAATGAAAAGGTGGACCGATCTT
TACATGAGATGCGTGAACTAGCGCAAGGAGCTTTAAAAGAAATGAGGACGTTAATTTGGCAACTACGTCCAGCAGGTTTA
GAGAAAGGATTATTACCAGCTTTAAAGCAATATGGTGAAAGTTTGGGGTTGAAAATTCGGGAACAAGTTACAGGTGTCCG
AGATTTGCCGCGCGTAGTAGAGGAAGCGTTATGGAGAATTGGACAAGAAGCTTTAAATAACGTAAGTAAGCATGCGAATG
TTAGAGAAGCGACGATTTATTTCAAAGTGACCGAGAAGAATGTATCATTAGAAATAGTCGATCAAGGAAACGGCTTTGTA
GAAAAGAATATAAAAGAGAAGAAATCACTTGGCATGACTACGATGCGCGAAAGAGTAGAATTAGTCGGTGGAACAATTAA
AATTGTAAGTGATAAAAAAAGAACAAGTGTAAAAGTAAACGTACCATTATGA

Upstream 100 bases:

>100_bases
ATGTTTTCACCATTATATCAATGTTATGAATAAGTACAAAGTGAAAAGTAGATGATTTATGTTAGGAACTATGTAAAATC
TTGTATGTAGGAGACGAATT

Downstream 100 bases:

>100_bases
TGTGAAAATGAGGGAAGTTTGTGAAAATAAAAGTATTATTAGTTGATGATCATACAGTCGTTTTAAAAGGATTAGCGTTT
TTCTTAAGTACACAGGAAGA

Product: two-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVVFFIREEEELSLRASYCQEELH
EDIKEAAKEALEKGELILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVNTIDVLQAITNHISFVIENLR
LNEQRRELVRMEERNRLARDLHDSVSQKLFSLNFMTKGAEAVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGL
EKGLLPALKQYGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
EKNIKEKKSLGMTTMRERVELVGGTIKIVSDKKRTSVKVNVPL

Sequences:

>Translated_523_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVVFFIREEEELSLRASYCQEELH
EDIKEAAKEALEKGELILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVNTIDVLQAITNHISFVIENLR
LNEQRRELVRMEERNRLARDLHDSVSQKLFSLNFMTKGAEAVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGL
EKGLLPALKQYGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
EKNIKEKKSLGMTTMRERVELVGGTIKIVSDKKRTSVKVNVPL
>Mature_523_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVVFFIREEEELSLRASYCQEELH
EDIKEAAKEALEKGELILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVNTIDVLQAITNHISFVIENLR
LNEQRRELVRMEERNRLARDLHDSVSQKLFSLNFMTKGAEAVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGL
EKGLLPALKQYGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
EKNIKEKKSLGMTTMRERVELVGGTIKIVSDKKRTSVKVNVPL

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=197, Percent_Identity=27.4111675126904, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788812, Length=240, Percent_Identity=26.25, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59809; Mature: 59809

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKL
CCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEE
IDYQLPEALTYENKRPMCEGECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGIL
EECCCCHHHCCCCCCCCCCCCCEEEECHHCHHHHHHHHHHHHHHCCCCEEECCCCCCCCE
HHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAFQIGTALKRAKLYENEKRRAH
EECCEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
YYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVVFFIREEEELSLRASYCQEELH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHH
EDIKEAAKEALEKGELILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVN
HHHHHHHHHHHHCCCEEEECCHHHHHHHCCCEEEEECEEEEEEEEEEEEEECCCCCCCCH
TIDVLQAITNHISFVIENLRLNEQRRELVRMEERNRLARDLHDSVSQKLFSLNFMTKGAE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGLEKGLLPALKQYGESLGLKIR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHH
EQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCCCC
EKNIKEKKSLGMTTMRERVELVGGTIKIVSDKKRTSVKVNVPL
HHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCEEEEECCC
>Mature Secondary Structure
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKL
CCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEE
IDYQLPEALTYENKRPMCEGECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGIL
EECCCCHHHCCCCCCCCCCCCCEEEECHHCHHHHHHHHHHHHHHCCCCEEECCCCCCCCE
HHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAFQIGTALKRAKLYENEKRRAH
EECCEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
YYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVVFFIREEEELSLRASYCQEELH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHH
EDIKEAAKEALEKGELILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVN
HHHHHHHHHHHHCCCEEEECCHHHHHHHCCCEEEEECEEEEEEEEEEEEEECCCCCCCCH
TIDVLQAITNHISFVIENLRLNEQRRELVRMEERNRLARDLHDSVSQKLFSLNFMTKGAE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGLEKGLLPALKQYGESLGLKIR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHH
EQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCCCC
EKNIKEKKSLGMTTMRERVELVGGTIKIVSDKKRTSVKVNVPL
HHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]