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The map label for this gene is pbpG [H]

Identifier: 118480405

GI number: 118480405

Start: 5140517

End: 5142589

Strand: Direct

Name: pbpG [H]

Synonym: BALH_4871

Alternate gene names: 118480405

Gene position: 5140517-5142589 (Clockwise)

Preceding gene: 118480404

Following gene: 118480408

Centisome position: 97.78

GC content: 38.4

Gene sequence:

>2073_bases
ATGAATGAGGGGCTGAAAAAGATGGATCAAACTATGAATCCGAAACTTAAAAAATATAAACGTCTTTTCTTCACCGTAAT
GTTTTCTTCTGTTCTTTTTTTCGTTTTCTCCTTTTTTGTTATTATTATAGTTGCAAAAATTATGGGACCTCCTCCTGTTG
CTGTCCCGCAAACAAGTGTCTTTTACGCTAATGATGACACTGTTATAGGACAAAGTAATCAGGTACAAAAACGCTACAAT
GTATCTCTCAGTGAAATTTCTCCTTATGTAAAAGAGGCAACACTATCTATCGAAGATCAACGATTCTACAAACATCATGG
CTTTGATATGAAGCGTATTGCTGGTGCCATTGTTGCCGATTTAAAAGCGATGGCAAAAGTCCAAGGTGCTAGTACGATTA
CACAACAATACGCACGTAATCTGTATTTAGATCATGATAAAACGTGGAAACGTAAACTATTAGAAGCAATGTACACAATC
CGCCTTGAAGTAAACTATAATAAAAATCATATTTTAGAAGGATATTTAAATACAATTTATTACGGGCATGGTGCTTACGG
AATCGAAGCTGCGTCTCGTCTATATTTCGATAAAACAGCAAAAGAATTAACATTAGCGGAGGCTAGTATGCTCGCAGGTA
TCCCGAAAGGACCTAGTGTCTATTCTCCCTTTTTAAAAGAAGATCGTGCAAAAGGACGACAATCTCTCATATTAGATGAA
ATGGTAGAACAAGGTTATATTACGAAGAAACAAGCAGCTTCAGCGAAGAAGGAGTCACTAACTTTCGCCTCATTAGATAC
GAAAAAAGTGGCAGAGGTTGCACCTTATTTCCAAGATGCTGTACAAGCTTCTCTTCTTCGTGATGTCGGATTAGATGAGC
AAGCGTTACAAAAAGGTGGCTTGCGTATTTATACAACGCTAGACCCGAAATTACAATCGGTTGCAGAGCAAGCTGTAAAA
GACCACATACCTGACACAACAAACATACAAACTGCTCTCGTTTCTATGAATCCAAAAACAGGCGAAGTAGCTGCCCTTGT
CGGGGGAACTGATTATAATAAGAGTCAATTTAACAGGGCTACACAGGCCGCTCGTCAGCCTGGATCTACGTTTAAGCCAT
TCCTATATTATGCGGCATTAGAACGAGGATTCACCCCCGCTACGCGCTTAAAAAGTGAGTACACTGTGTTCACTTTAGGT
GACGGTGTTTCAAAGTATAAACCGAAAAACTATAAGGACTATTATGCAGACGATTTTGTCACAATGGCGCAGGCTCTTGC
AGTCTCTGATAACATCTATGCCGTGAAGACCAATTTATTTTTAGGCGAAGATATTCTTACAAAAACAGCGAAGCAATTCG
GAATTAAGAGTGCATTAAAAGACGTCCCTTCTCTTGCTCTCGGTACATCTCCTGTAAAACCAATTGAAATGGTTAACGCT
TATAGCATGTTCGCAAATGGTGGAAAAGAAGTAAAACCTACTTTCATTCGCCGCATTATGGATCATGAAGGAAATGTATT
ATACGATGCTCATTTGGAGAGTAAACAAGTTCTCGACAAAAGCAAAGCATTTGTAATGGAAGAAATGATGACGGGCATGT
TTAATAAAAAGCTAAGTAGTTATGCTGCTGTAACTGGTCAATCGATGTTATCTAAACTATCCAGAACCTATGCCGGAAAA
TCTGGTTCTACTGAAACAGATAGTTGGATGATTGGGTTTACCCCGCAAATCGTAACGGGTGTATGGGTTGGATATGATCA
ACCTAAATCAATTTCAAACGTAGCAGAACAAGGATATGCGAAAAGAATATGGACCGATACGATGGAAAAAGGCTTAGATG
GACAACCTAAAAAAGAGTTTAAACAGCCAAGTGACGTCGTAGCAGTCGATATTAACCCTGAAAACGGGAAAATTGCTACA
AAAAATTGTCCAATTTCAGTGAAAATGTATTTTGCTAAAGGTACCGAGCCTACAGAATATTGTATGGATCATGTCGATGA
TAAAGAAGAATTTGAAAAGACAAGTGAAGAAAAGAAAAAAACAAGTTGGTGGAAAAAATATCTTCCTTGGTGA

Upstream 100 bases:

>100_bases
TGCCTTTGAGCTCCTTTCTTAATTGAAGGAGCTTTTTGTTTTCAAAATTTCATTGTTTAAAATAACCGAAAACCCTCAAT
ACTAATACAATAATGTTTGT

Downstream 100 bases:

>100_bases
CACACGAGGCTATTCCAATAAAATGTGGAATAGCCTTTATTGTCATTCTTTGTCGGTAAATCGATATTCCTTGTCGAATC
GTCGATATATCAAAAAAAAT

Product: penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MNEGLKKMDQTMNPKLKKYKRLFFTVMFSSVLFFVFSFFVIIIVAKIMGPPPVAVPQTSVFYANDDTVIGQSNQVQKRYN
VSLSEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTWKRKLLEAMYTI
RLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQSLILDE
MVEQGYITKKQAASAKKESLTFASLDTKKVAEVAPYFQDAVQASLLRDVGLDEQALQKGGLRIYTTLDPKLQSVAEQAVK
DHIPDTTNIQTALVSMNPKTGEVAALVGGTDYNKSQFNRATQAARQPGSTFKPFLYYAALERGFTPATRLKSEYTVFTLG
DGVSKYKPKNYKDYYADDFVTMAQALAVSDNIYAVKTNLFLGEDILTKTAKQFGIKSALKDVPSLALGTSPVKPIEMVNA
YSMFANGGKEVKPTFIRRIMDHEGNVLYDAHLESKQVLDKSKAFVMEEMMTGMFNKKLSSYAAVTGQSMLSKLSRTYAGK
SGSTETDSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGYAKRIWTDTMEKGLDGQPKKEFKQPSDVVAVDINPENGKIAT
KNCPISVKMYFAKGTEPTEYCMDHVDDKEEFEKTSEEKKKTSWWKKYLPW

Sequences:

>Translated_690_residues
MNEGLKKMDQTMNPKLKKYKRLFFTVMFSSVLFFVFSFFVIIIVAKIMGPPPVAVPQTSVFYANDDTVIGQSNQVQKRYN
VSLSEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTWKRKLLEAMYTI
RLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQSLILDE
MVEQGYITKKQAASAKKESLTFASLDTKKVAEVAPYFQDAVQASLLRDVGLDEQALQKGGLRIYTTLDPKLQSVAEQAVK
DHIPDTTNIQTALVSMNPKTGEVAALVGGTDYNKSQFNRATQAARQPGSTFKPFLYYAALERGFTPATRLKSEYTVFTLG
DGVSKYKPKNYKDYYADDFVTMAQALAVSDNIYAVKTNLFLGEDILTKTAKQFGIKSALKDVPSLALGTSPVKPIEMVNA
YSMFANGGKEVKPTFIRRIMDHEGNVLYDAHLESKQVLDKSKAFVMEEMMTGMFNKKLSSYAAVTGQSMLSKLSRTYAGK
SGSTETDSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGYAKRIWTDTMEKGLDGQPKKEFKQPSDVVAVDINPENGKIAT
KNCPISVKMYFAKGTEPTEYCMDHVDDKEEFEKTSEEKKKTSWWKKYLPW
>Mature_690_residues
MNEGLKKMDQTMNPKLKKYKRLFFTVMFSSVLFFVFSFFVIIIVAKIMGPPPVAVPQTSVFYANDDTVIGQSNQVQKRYN
VSLSEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVADLKAMAKVQGASTITQQYARNLYLDHDKTWKRKLLEAMYTI
RLEVNYNKNHILEGYLNTIYYGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQSLILDE
MVEQGYITKKQAASAKKESLTFASLDTKKVAEVAPYFQDAVQASLLRDVGLDEQALQKGGLRIYTTLDPKLQSVAEQAVK
DHIPDTTNIQTALVSMNPKTGEVAALVGGTDYNKSQFNRATQAARQPGSTFKPFLYYAALERGFTPATRLKSEYTVFTLG
DGVSKYKPKNYKDYYADDFVTMAQALAVSDNIYAVKTNLFLGEDILTKTAKQFGIKSALKDVPSLALGTSPVKPIEMVNA
YSMFANGGKEVKPTFIRRIMDHEGNVLYDAHLESKQVLDKSKAFVMEEMMTGMFNKKLSSYAAVTGQSMLSKLSRTYAGK
SGSTETDSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGYAKRIWTDTMEKGLDGQPKKEFKQPSDVVAVDINPENGKIAT
KNCPISVKMYFAKGTEPTEYCMDHVDDKEEFEKTSEEKKKTSWWKKYLPW

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=537, Percent_Identity=29.4227188081937, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI87082258, Length=265, Percent_Identity=39.2452830188679, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1788867, Length=605, Percent_Identity=27.603305785124, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI1789601, Length=165, Percent_Identity=38.7878787878788, Blast_Score=125, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 77405; Mature: 77405

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEGLKKMDQTMNPKLKKYKRLFFTVMFSSVLFFVFSFFVIIIVAKIMGPPPVAVPQTSV
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
FYANDDTVIGQSNQVQKRYNVSLSEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVAD
EEECCCEEECCCHHHHHHHCCCHHHHCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
LKAMAKVQGASTITQQYARNLYLDHDKTWKRKLLEAMYTIRLEVNYNKNHILEGYLNTIY
HHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHEE
YGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQSLILDE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCHHHHHHHHCHHHHHHHHH
MVEQGYITKKQAASAKKESLTFASLDTKKVAEVAPYFQDAVQASLLRDVGLDEQALQKGG
HHHCCCCCHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
LRIYTTLDPKLQSVAEQAVKDHIPDTTNIQTALVSMNPKTGEVAALVGGTDYNKSQFNRA
EEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHH
TQAARQPGSTFKPFLYYAALERGFTPATRLKSEYTVFTLGDGVSKYKPKNYKDYYADDFV
HHHHHCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCHHHCCCCCCCCHHHHHHH
TMAQALAVSDNIYAVKTNLFLGEDILTKTAKQFGIKSALKDVPSLALGTSPVKPIEMVNA
HHHHHHHHCCCEEEEEECEEECHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHH
YSMFANGGKEVKPTFIRRIMDHEGNVLYDAHLESKQVLDKSKAFVMEEMMTGMFNKKLSS
HHHHHCCCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAAVTGQSMLSKLSRTYAGKSGSTETDSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGYA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHEEECCCCCHHHHHHHHHHHH
KRIWTDTMEKGLDGQPKKEFKQPSDVVAVDINPENGKIATKNCPISVKMYFAKGTEPTEY
HHHHHHHHHCCCCCCCHHHHCCCCCEEEEEECCCCCEEEECCCCEEEEEEEECCCCHHHH
CMDHVDDKEEFEKTSEEKKKTSWWKKYLPW
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNEGLKKMDQTMNPKLKKYKRLFFTVMFSSVLFFVFSFFVIIIVAKIMGPPPVAVPQTSV
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
FYANDDTVIGQSNQVQKRYNVSLSEISPYVKEATLSIEDQRFYKHHGFDMKRIAGAIVAD
EEECCCEEECCCHHHHHHHCCCHHHHCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
LKAMAKVQGASTITQQYARNLYLDHDKTWKRKLLEAMYTIRLEVNYNKNHILEGYLNTIY
HHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHEE
YGHGAYGIEAASRLYFDKTAKELTLAEASMLAGIPKGPSVYSPFLKEDRAKGRQSLILDE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCHHHHHHHHCHHHHHHHHH
MVEQGYITKKQAASAKKESLTFASLDTKKVAEVAPYFQDAVQASLLRDVGLDEQALQKGG
HHHCCCCCHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
LRIYTTLDPKLQSVAEQAVKDHIPDTTNIQTALVSMNPKTGEVAALVGGTDYNKSQFNRA
EEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHH
TQAARQPGSTFKPFLYYAALERGFTPATRLKSEYTVFTLGDGVSKYKPKNYKDYYADDFV
HHHHHCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCHHHCCCCCCCCHHHHHHH
TMAQALAVSDNIYAVKTNLFLGEDILTKTAKQFGIKSALKDVPSLALGTSPVKPIEMVNA
HHHHHHHHCCCEEEEEECEEECHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHH
YSMFANGGKEVKPTFIRRIMDHEGNVLYDAHLESKQVLDKSKAFVMEEMMTGMFNKKLSS
HHHHHCCCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAAVTGQSMLSKLSRTYAGKSGSTETDSWMIGFTPQIVTGVWVGYDQPKSISNVAEQGYA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHEEECCCCCHHHHHHHHHHHH
KRIWTDTMEKGLDGQPKKEFKQPSDVVAVDINPENGKIATKNCPISVKMYFAKGTEPTEY
HHHHHHHHHCCCCCCCHHHHCCCCCEEEEEECCCCCEEEECCCCEEEEEEEECCCCHHHH
CMDHVDDKEEFEKTSEEKKKTSWWKKYLPW
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]