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The map label for this gene is argS [H]

Identifier: 118480395

GI number: 118480395

Start: 5130457

End: 5132127

Strand: Reverse

Name: argS [H]

Synonym: BALH_4860

Alternate gene names: 118480395

Gene position: 5132127-5130457 (Counterclockwise)

Preceding gene: 118480396

Following gene: 118480394

Centisome position: 97.62

GC content: 38.66

Gene sequence:

>1671_bases
ATGAATTCTTTAGAACAAGTAAAAGGATTGATTAAAGAAGAAATTCAAGCTGCTGTATTAAAGGCAGAATTAGCGACAGA
AGAACAGATTCCAAACGTTGTATTAGAATCTCCAAAAGATAAAACAAACGGTGACTTCTCTACAAATATGGCAATGCAAC
TTGCACGCGTTGCGAAAAAAGCACCTCGTATGATTGCAGAAGAACTAGTTGCAAACTTCGATAAAGCAAAAGCTTCTATT
GAAAAAATTGAAATCGCAGGTCCTGGTTTTATTAACTTCTACATGGATAATAGCTACTTAACAGACTTAATCCCAACAAT
CGTTAACGCTGGTGAAGCTTACGGTGAAACGAATACTGGTAAAGGTGAAAAAGTACAAGTTGAGTTCGTATCTGCAAATC
CAACAGGTGATCTTCACTTAGGACATGCACGTGGTGCAGCGGTAGGTGACACTTTATGTAACTTATTAGCAAAAGCAGGA
TACGATGTATCTCGTGAGTACTACATTAATGACGCTGGTAACCAAATTCATAACTTAGCTCTTTCTGTTAAAGCTCGTTA
CATGCAAGCTTTAGGTCTAGAGAAAGAAATGCCAGAAGACGGATACCACGGTGCGGACATCATTGCAATCGGTAAACGTT
TAGCAGAAGAATTTGGCGATCGTTATGCGAAAGCTGATGAAAAAGAAAGCTATGAATTCTACCGTGAGTACGGTTTAAAA
TATGAATTAGCAAAACTTCAAAAAGACTTAGAAAGCTTCCGTGTTAAATTTGATGTATGGTTCTCAGAAACATCATTATA
CAAAAACGGAAAAATCGATCAAGCTCTTGCAGTATTAAAAGAGCGCGATGAGATCTTTGAAGAAGATGGAGCAACTTGGT
TCCGTTCAATGACTTACGGTGATGATAAAAACCGTGTACTAATTAAAAACGATGGTTCTTACACGTACTTAACACCAGAT
ATCGCGTATCACCGTGATAAATTAGAGCGTGGTTTCGATAAGTTAATCAACATTTGGGGCGCTGACCACCATGGTTACAT
TCCTCGTATGAAAGCTGCTATTCAAGCGCTAGGTTACGATAAAGAAACACTTGAAGTAGAAATCATCCAAATGGTACAAC
TGTATCAAAATGGTGAAAAAATGAAGATGAGTAAGCGTACAGGTAAAGCAGTTACACTTCGTGAGCTTATGGAAGAAGTA
GGCGTGGACGCAATGCGTTACTTCTTCGCAATGCGTAGCGGTGATTCGCATTTAGACTTCGATATGGACTTAGCTGTATC
AAAATCTAATGAAAACCCAGTATACTATGCACAATATGCTCATGCTCGTGTATGCAGTATCCTTCGTCAAGGTGAAGAGT
TAGGATTAGCTACAGACGGAGACGTGAACTACAAACTTGTTACTTCTGAGAAAGAAGTAGAGTTACTGAAAAAACTTGGT
GAATTCCCAGCAGTAGTTGCGGATGCAGCACAAAAACGTCTACCACACCGCATTACAAACTATGCATTTGAATTAGCAGC
GGCATTACACAGCTTCTACAATGCAGAAAAAGTATTAAACCAAGATAACGTAGAATTAAGTAAAGCTCGTTACGAGTTAA
TGAAAGCAGTACGCACTACACTTCAAAACGCATTAGCAATCGTAGGAGTATCTGCACCAGAAAAAATGTAA

Upstream 100 bases:

>100_bases
AAAAGAAAAAAGGACAACTTTTCTTAACGTACGCATTGCTTCTAAGTGAACAAGAAGCTGGCAGATATACAATTACAATT
AATTTGAAGGAGGCAAAATA

Downstream 100 bases:

>100_bases
TAAAGAAAAGCGGACTTTCGCTTTCAGTAAAAGGCAATCACACAATGTTGTGATTGCCTTTTTGTATGGAGATAATAAAA
AAATAAAATTTTATCAAACA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase 1; ArgRS 1 [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MNSLEQVKGLIKEEIQAAVLKAELATEEQIPNVVLESPKDKTNGDFSTNMAMQLARVAKKAPRMIAEELVANFDKAKASI
EKIEIAGPGFINFYMDNSYLTDLIPTIVNAGEAYGETNTGKGEKVQVEFVSANPTGDLHLGHARGAAVGDTLCNLLAKAG
YDVSREYYINDAGNQIHNLALSVKARYMQALGLEKEMPEDGYHGADIIAIGKRLAEEFGDRYAKADEKESYEFYREYGLK
YELAKLQKDLESFRVKFDVWFSETSLYKNGKIDQALAVLKERDEIFEEDGATWFRSMTYGDDKNRVLIKNDGSYTYLTPD
IAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYDKETLEVEIIQMVQLYQNGEKMKMSKRTGKAVTLRELMEEV
GVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLATDGDVNYKLVTSEKEVELLKKLG
EFPAVVADAAQKRLPHRITNYAFELAAALHSFYNAEKVLNQDNVELSKARYELMKAVRTTLQNALAIVGVSAPEKM

Sequences:

>Translated_556_residues
MNSLEQVKGLIKEEIQAAVLKAELATEEQIPNVVLESPKDKTNGDFSTNMAMQLARVAKKAPRMIAEELVANFDKAKASI
EKIEIAGPGFINFYMDNSYLTDLIPTIVNAGEAYGETNTGKGEKVQVEFVSANPTGDLHLGHARGAAVGDTLCNLLAKAG
YDVSREYYINDAGNQIHNLALSVKARYMQALGLEKEMPEDGYHGADIIAIGKRLAEEFGDRYAKADEKESYEFYREYGLK
YELAKLQKDLESFRVKFDVWFSETSLYKNGKIDQALAVLKERDEIFEEDGATWFRSMTYGDDKNRVLIKNDGSYTYLTPD
IAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYDKETLEVEIIQMVQLYQNGEKMKMSKRTGKAVTLRELMEEV
GVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLATDGDVNYKLVTSEKEVELLKKLG
EFPAVVADAAQKRLPHRITNYAFELAAALHSFYNAEKVLNQDNVELSKARYELMKAVRTTLQNALAIVGVSAPEKM
>Mature_556_residues
MNSLEQVKGLIKEEIQAAVLKAELATEEQIPNVVLESPKDKTNGDFSTNMAMQLARVAKKAPRMIAEELVANFDKAKASI
EKIEIAGPGFINFYMDNSYLTDLIPTIVNAGEAYGETNTGKGEKVQVEFVSANPTGDLHLGHARGAAVGDTLCNLLAKAG
YDVSREYYINDAGNQIHNLALSVKARYMQALGLEKEMPEDGYHGADIIAIGKRLAEEFGDRYAKADEKESYEFYREYGLK
YELAKLQKDLESFRVKFDVWFSETSLYKNGKIDQALAVLKERDEIFEEDGATWFRSMTYGDDKNRVLIKNDGSYTYLTPD
IAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYDKETLEVEIIQMVQLYQNGEKMKMSKRTGKAVTLRELMEEV
GVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLATDGDVNYKLVTSEKEVELLKKLG
EFPAVVADAAQKRLPHRITNYAFELAAALHSFYNAEKVLNQDNVELSKARYELMKAVRTTLQNALAIVGVSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=607, Percent_Identity=25.0411861614498, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1788184, Length=603, Percent_Identity=24.8756218905473, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71985061, Length=582, Percent_Identity=24.0549828178694, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71985068, Length=537, Percent_Identity=24.3947858472998, Blast_Score=106, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320548, Length=551, Percent_Identity=24.8638838475499, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321883, Length=570, Percent_Identity=23.1578947368421, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18859963, Length=588, Percent_Identity=24.3197278911565, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571570, Length=491, Percent_Identity=24.2362525458248, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62530; Mature: 62530

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLEQVKGLIKEEIQAAVLKAELATEEQIPNVVLESPKDKTNGDFSTNMAMQLARVAKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHH
APRMIAEELVANFDKAKASIEKIEIAGPGFINFYMDNSYLTDLIPTIVNAGEAYGETNTG
HHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHHHHHHCCHHCCCCCCC
KGEKVQVEFVSANPTGDLHLGHARGAAVGDTLCNLLAKAGYDVSREYYINDAGNQIHNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHH
LSVKARYMQALGLEKEMPEDGYHGADIIAIGKRLAEEFGDRYAKADEKESYEFYREYGLK
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
YELAKLQKDLESFRVKFDVWFSETSLYKNGKIDQALAVLKERDEIFEEDGATWFRSMTYG
HHHHHHHHHHHHHEEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
DDKNRVLIKNDGSYTYLTPDIAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYD
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
KETLEVEIIQMVQLYQNGEKMKMSKRTGKAVTLRELMEEVGVDAMRYFFAMRSGDSHLDF
CHHHHHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
DMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLATDGDVNYKLVTSEKEVELLKKLG
CEEEEEECCCCCCEEEEHHHHHHHHHHHHCCHHCCCCCCCCCCEEEECCHHHHHHHHHHC
EFPAVVADAAQKRLPHRITNYAFELAAALHSFYNAEKVLNQDNVELSKARYELMKAVRTT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LQNALAIVGVSAPEKM
HHHHHHEEECCCCCCC
>Mature Secondary Structure
MNSLEQVKGLIKEEIQAAVLKAELATEEQIPNVVLESPKDKTNGDFSTNMAMQLARVAKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHH
APRMIAEELVANFDKAKASIEKIEIAGPGFINFYMDNSYLTDLIPTIVNAGEAYGETNTG
HHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHHHHHHCCHHCCCCCCC
KGEKVQVEFVSANPTGDLHLGHARGAAVGDTLCNLLAKAGYDVSREYYINDAGNQIHNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHH
LSVKARYMQALGLEKEMPEDGYHGADIIAIGKRLAEEFGDRYAKADEKESYEFYREYGLK
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
YELAKLQKDLESFRVKFDVWFSETSLYKNGKIDQALAVLKERDEIFEEDGATWFRSMTYG
HHHHHHHHHHHHHEEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
DDKNRVLIKNDGSYTYLTPDIAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYD
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
KETLEVEIIQMVQLYQNGEKMKMSKRTGKAVTLRELMEEVGVDAMRYFFAMRSGDSHLDF
CHHHHHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
DMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLATDGDVNYKLVTSEKEVELLKKLG
CEEEEEECCCCCCEEEEHHHHHHHHHHHHCCHHCCCCCCCCCCEEEECCHHHHHHHHHHC
EFPAVVADAAQKRLPHRITNYAFELAAALHSFYNAEKVLNQDNVELSKARYELMKAVRTT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LQNALAIVGVSAPEKM
HHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]