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The map label for this gene is nuoD

Identifier: 118480337

GI number: 118480337

Start: 5058289

End: 5059389

Strand: Reverse

Name: nuoD

Synonym: BALH_4800

Alternate gene names: 118480337

Gene position: 5059389-5058289 (Counterclockwise)

Preceding gene: 118480338

Following gene: 118480336

Centisome position: 96.24

GC content: 43.87

Gene sequence:

>1101_bases
ATGATCCGTACGGAAGAAATGCTTTTGAATGTAGGTCCTCAGCATCCGAGTACGCACGGTGTGTTCAGGCTTGTTATTAA
GATTGACGGGGAAATTATTAAAGAAGCTACACCGGTTATTGGATATTTGCATCGCGGGACCGAAAAGATTGCAGAGAGCT
TACAGTATACGCAAATTATCCCTTATACAGATCGGATGGATTATTTATCGGCTATGACGAATAATTACGTCATTTGCCAT
GCTGTAGAGACGATGATAGGGCTTGAAATCCCGGAGCGGGCCGAATACTTGCGAGTACTTGCAATGGAGCTTGGAAGGAT
TGCGAGCCACCTCGTTTGGTGGGGGACAAATCTTCTTGATATAGGAGCAGTTAGCCCGTTTTTGTACGCGTTCCGTGAGC
GAGAAATGATTATTAATTTATTAAACGAATTATGCGGTGCACGGCTTACTTTTAATTATATGAGGGTCGGCGGTGTGAAA
TGGGATGCACCGGATGGTTGGATTGAAAAAGTGGAAGAGTTTGTTCCGTATATGAGAGAACAATTGGCAGGGTATCATGA
TCTTGTTAGCGGCAATGAGATTTTCTTAAATCGTGTAAAAGGCGTTGGTATATATAGTGCGGAGGAAGCGATTTCGTATT
CTTTAAGCGGAGCGAATTTGCGGTGTACCGGAGTAAACTGGGATCTTCGCAAGGATGAACCATATTCCATTTACAATCGT
TTTGACTTTGATATTCCTGTTGGAAGCGTGGGGGATGCTTGGGATCGCTACGTTTGCCGCATGCAGGAAATTGAGGAGTC
TTTAAAGATTGTTGAGCAAGCAGTCCAGCAGTTCCCAAAAGAAGGAGCTGTGCTGGCGAAAGTGCCGAAAATTATTAAGG
CGCCTAAAGGAGAAGCATTCGTCCGTATAGAGTCGCCGCGCGGAGAGATTGGTTGCTATATTGCTAGTGATGGGAAGAAA
GAGCCGTACCGTTTGAAGTTTCGCAGGCCGTCTTTTTACAATTTGCAAATTTTACCGAAGTTATTAAAAGGTGAAAACAT
CGCCAATTTAATTACGATTTTAGGTGGAGTGGATATTGTACTTGGGGAGGTTGATGGCTAA

Upstream 100 bases:

>100_bases
AAGGGGCATCCGAATTTATCACGTATTTTAATGCCTGATGATTGGGTAGGGCACCCGCTTAGGAAAGATTATGAACCGTA
TGATGTGGAGGTGTAGCTAA

Downstream 100 bases:

>100_bases
TGATTGAAACGCTCTTACAATCACCTTCAAGCTGGACGAATTTCTTCATTTTTTTCGGATTAGCGGTGCTCCTATTATTT
GCAGTCCTTGGCTTCGTTAC

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICH
AVETMIGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVK
WDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYNR
FDFDIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKK
EPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG

Sequences:

>Translated_366_residues
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICH
AVETMIGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVK
WDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYNR
FDFDIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKK
EPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG
>Mature_366_residues
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICH
AVETMIGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVK
WDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYNR
FDFDIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKK
EPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=385, Percent_Identity=39.2207792207792, Blast_Score=307, Evalue=1e-83,
Organism=Homo sapiens, GI260898743, Length=380, Percent_Identity=38.4210526315789, Blast_Score=296, Evalue=3e-80,
Organism=Escherichia coli, GI145693162, Length=385, Percent_Identity=38.7012987012987, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI1789076, Length=351, Percent_Identity=26.7806267806268, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788832, Length=358, Percent_Identity=25.6983240223464, Blast_Score=128, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17568379, Length=386, Percent_Identity=39.119170984456, Blast_Score=309, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI17555284, Length=386, Percent_Identity=38.3419689119171, Blast_Score=308, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24638644, Length=384, Percent_Identity=40.3645833333333, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI221459469, Length=382, Percent_Identity=39.0052356020942, Blast_Score=310, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_BACAH (A0RL88)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_897488.1
- ProteinModelPortal:   A0RL88
- SMR:   A0RL88
- STRING:   A0RL88
- EnsemblBacteria:   EBBACT00000070417
- GeneID:   4543206
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_4800
- NMPDR:   fig|412694.5.peg.4611
- eggNOG:   COG0649
- GeneTree:   EBGT00050000003635
- HOGENOM:   HBG459705
- OMA:   GVFIQGN
- ProtClustDB:   PRK12322
- BioCyc:   BTHU412694:BALH_4800-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 41488; Mature: 41488

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQII
CCCCHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
PYTDRMDYLSAMTNNYVICHAVETMIGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLD
CCCCHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
IGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVKWDAPDGWIEKVEEFVPYMRE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCEEECCCCHHHHHHHHHHHHHHH
QLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYNR
HHCCHHHHCCCCCEEEEHHCCCCEEEHHHHHEEEECCCEEEEECCCCCCCCCCCCCHHCE
FDFDIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAF
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEE
VRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIV
EEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCEEE
LGEVDG
EEECCC
>Mature Secondary Structure
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQII
CCCCHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
PYTDRMDYLSAMTNNYVICHAVETMIGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLD
CCCCHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
IGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVKWDAPDGWIEKVEEFVPYMRE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCEEECCCCHHHHHHHHHHHHHHH
QLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYNR
HHCCHHHHCCCCCEEEEHHCCCCEEEHHHHHEEEECCCEEEEECCCCCCCCCCCCCHHCE
FDFDIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAF
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEE
VRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIV
EEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCEEE
LGEVDG
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA