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The map label for this gene is gtaB [H]

Identifier: 118480317

GI number: 118480317

Start: 5035626

End: 5036501

Strand: Reverse

Name: gtaB [H]

Synonym: BALH_4779

Alternate gene names: 118480317

Gene position: 5036501-5035626 (Counterclockwise)

Preceding gene: 118480318

Following gene: 118480316

Centisome position: 95.8

GC content: 36.3

Gene sequence:

>876_bases
ATGAAAAAAGTAAGAAAAGCAATTATCCCAGCTGCTGGTCTAGGGACGAGATTTTTACCAGCGACAAAAGCGATGCCGAA
AGAAATGTTGCCAATCGTTGATAAGCCGACAATTCAATACATAATAGAAGAAGCAATAGAATCAGGAATTGAAGATATTA
TTATTGTTACTGGAAAAGGAAAACGTGCGATTGAAGACCATTTTGATCATTCATTCGAACTAGAACAAAACCTTTTAGAA
AAAGGAAAGTACGAAATGCTTGAAAAGGTACAAGCTTCTTCAAGAATTAACATTCATTACATAAGACAAAAGGAACCGAA
AGGACTTGGGCATGCAGTGTGGTGTGCACGTAAGTTTATTGGAAATGAACCATTTGCGGTATTACTTGGTGACGATATTG
TACAAGCTGAAACGCCATGTTTACGTCAATTAATGGATCAATATGAAGGGACACAATCGTCGGTTATTGGTGTACAAACA
GTACCAGAACATGAAACACACCGTTACGGTATTATTGATCCAGTAGAACAAAATGAACGTCGTTATCAAGTGCGCCAGTT
TGTTGAAAAGCCAGCAAAAGGCACAGCGCCATCAAATTTAGCAATTATGGGTCGTTACGTATTAACGCCAGAAATTTTTA
CATTCCTTGAGAATCAACAAACGGGTGCTGGTGGAGAGATTCAGTTGACAGATGCAATTCAACGTTTAAATGAAATTCAG
CGTGTATTTGCTTATGATTTTGAAGGAACTCGTTATGATGTAGGGGAGAAATTTGGGTTTATTAAGACTACAATTGAAAT
GGCTTTAAAGCATGAAGAGTTAAGAGAAGAATTAATGAATTATATGAATGAACTTGTAAAAAAAGAAAAAATGTAG

Upstream 100 bases:

>100_bases
TTTATAATAGAAACTCTACCTATGGAGTTAGAAGAATGACTCTATAGGTAGGGTTTTTGTTATTGTTACATATAAATAAA
AGGATATAGGGGGGCTACAA

Downstream 100 bases:

>100_bases
GTATAAAGTGGGGTGGAAAGGTAGTGTCCTTGACTAAAGTATCGAGTGAAAGTGTAGAAAGACAAGAAATGCTTGGTGAT
GAAAATATAAATCAAAAACG

Product: UDP-glucose pyrophosphorylase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQNLLE
KGKYEMLEKVQASSRINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQT
VPEHETHRYGIIDPVEQNERRYQVRQFVEKPAKGTAPSNLAIMGRYVLTPEIFTFLENQQTGAGGEIQLTDAIQRLNEIQ
RVFAYDFEGTRYDVGEKFGFIKTTIEMALKHEELREELMNYMNELVKKEKM

Sequences:

>Translated_291_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQNLLE
KGKYEMLEKVQASSRINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQT
VPEHETHRYGIIDPVEQNERRYQVRQFVEKPAKGTAPSNLAIMGRYVLTPEIFTFLENQQTGAGGEIQLTDAIQRLNEIQ
RVFAYDFEGTRYDVGEKFGFIKTTIEMALKHEELREELMNYMNELVKKEKM
>Mature_291_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQNLLE
KGKYEMLEKVQASSRINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQT
VPEHETHRYGIIDPVEQNERRYQVRQFVEKPAKGTAPSNLAIMGRYVLTPEIFTFLENQQTGAGGEIQLTDAIQRLNEIQ
RVFAYDFEGTRYDVGEKFGFIKTTIEMALKHEELREELMNYMNELVKKEKM

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=292, Percent_Identity=44.5205479452055, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1788355, Length=277, Percent_Identity=41.1552346570397, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1788351, Length=270, Percent_Identity=29.6296296296296, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790224, Length=268, Percent_Identity=28.7313432835821, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320148, Length=288, Percent_Identity=25.3472222222222, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 33287; Mature: 33287

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKG
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDHSFELEQNLLEKGKYEMLEKVQASSRINIHYIRQKEPKGLGHAVWCARKFI
CHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
GNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPEHETHRYGIIDPVEQNER
CCCCEEEEECCCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHH
RYQVRQFVEKPAKGTAPSNLAIMGRYVLTPEIFTFLENQQTGAGGEIQLTDAIQRLNEIQ
HHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
RVFAYDFEGTRYDVGEKFGFIKTTIEMALKHEELREELMNYMNELVKKEKM
HHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKG
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDHSFELEQNLLEKGKYEMLEKVQASSRINIHYIRQKEPKGLGHAVWCARKFI
CHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
GNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPEHETHRYGIIDPVEQNER
CCCCEEEEECCCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHH
RYQVRQFVEKPAKGTAPSNLAIMGRYVLTPEIFTFLENQQTGAGGEIQLTDAIQRLNEIQ
HHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
RVFAYDFEGTRYDVGEKFGFIKTTIEMALKHEELREELMNYMNELVKKEKM
HHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]