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The map label for this gene is galE [H]

Identifier: 118480305

GI number: 118480305

Start: 5021758

End: 5022750

Strand: Reverse

Name: galE [H]

Synonym: BALH_4766

Alternate gene names: 118480305

Gene position: 5022750-5021758 (Counterclockwise)

Preceding gene: 118480306

Following gene: 118480304

Centisome position: 95.54

GC content: 39.27

Gene sequence:

>993_bases
ATGAATTCAATTCTAATCTGCGGCGGAGCTGGTTATATCGGTTCTCACGCTGTGAAAAAGTTAGTAGACGAAGGTTTATC
TGTAGTAGTAGTAGATAACTTACAAACGGGTCATGAGGATGCAATTACGGAAGGTGCGAAGTTTTATAATGGCGACCTTC
GTGATAAAGCATTTTTAAGAGATGTTTTTACACAAGAAAATATTGAGGCGGTTATGCATTTCGCGGCTGATTCTTTAGTT
GGAGTTAGTATGGAGAAGCCTCTTCAATATTATAATAACAATGTGTATGGTGCACTTTGCTTATTAGAGGTAATGGATGA
GTTTAAGGTAGATAAGTTTATTTTCTCTTCTACTGCGGCGACGTATGGTGAGGTAGATGTAGACCTTATTACTGAGGAAA
CGATGACAAATCCAACGAATACGTATGGAGAAACGAAGTTAGCAATCGAGAAGATGCTTCATTGGTATAGCCAAGCTTCT
AATTTACGTTATAAGATTTTCAGATACTTTAACGTAGCTGGTGCAACTCCAAATGGTATTATTGGGGAAGATCACCGTCC
AGAGACGCATTTAATTCCTCTTGTATTGCAAGTGGCGTTAGGTCAACGTGAGAAGATTATGATGTTTGGTGATGATTATA
ATACACCAGACGGTACTTGTATCCGTGATTATATTCATGTTGAAGATTTAGTAGCGGCTCACTTCTTAGGTCTTAAAGAC
CTACAGAACGGCGGAGAGAGTGATTTCTATAACTTAGGAAATGGTAATGGTTTCAGCGTAAAAGAAATCGTTGATGCAGT
TCGTGAAGTTACAAATCATGAAATTCCTGCTGAGGTAGCACCGCGCCGTGCGGGAGATCCAGCACGTTTAGTTGCTTCTT
CTCAGAAAGCGAAAGAGAAATTAGGTTGGGATCCTCAGTATGTAAATGTGAAGACAATCATTGAGCATGCTTGGAATTGG
CATCAGAAAAAACCTAATGGGTATGATAAGTAA

Upstream 100 bases:

>100_bases
TTGCTAAGTAATAAAGGTACACAAAAGGTATACGAGCAATCGTATACCTTTTATAATAAGAGAGTGAATAAGAAATCCTA
ATATATGTAGGAGGAAGACA

Downstream 100 bases:

>100_bases
TAATATTTTAAACCTCAAAAAGTAGTTTTTAACTACTCTTTGAGGTTTTTTGTTTATGTAAAAATGAACAAATTCGAAAC
AATAAAATCCCCTCATTCAG

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVFTQENIEAVMHFAADSLV
GVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQAS
NLRYKIFRYFNVAGATPNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEKLGWDPQYVNVKTIIEHAWNW
HQKKPNGYDK

Sequences:

>Translated_330_residues
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVFTQENIEAVMHFAADSLV
GVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQAS
NLRYKIFRYFNVAGATPNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEKLGWDPQYVNVKTIIEHAWNW
HQKKPNGYDK
>Mature_330_residues
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVFTQENIEAVMHFAADSLV
GVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQAS
NLRYKIFRYFNVAGATPNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEKLGWDPQYVNVKTIIEHAWNW
HQKKPNGYDK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=37.5366568914956, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=37.5366568914956, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=37.5366568914956, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI7657641, Length=336, Percent_Identity=27.9761904761905, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI42516563, Length=307, Percent_Identity=26.0586319218241, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=35.8208955223881, Blast_Score=220, Evalue=9e-59,
Organism=Escherichia coli, GI48994969, Length=337, Percent_Identity=29.3768545994065, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=27.5964391691395, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1790049, Length=276, Percent_Identity=30.0724637681159, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=36.9186046511628, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=36.7052023121387, Blast_Score=227, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17539532, Length=313, Percent_Identity=24.6006389776358, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=325, Percent_Identity=26.7692307692308, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=324, Percent_Identity=26.5432098765432, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=41.1078717201166, Blast_Score=251, Evalue=2e-67,
Organism=Drosophila melanogaster, GI19923002, Length=349, Percent_Identity=39.541547277937, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI21356223, Length=310, Percent_Identity=24.5161290322581, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36872; Mature: 36872

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLR
CCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHCCHHHCCCCCCHHHHHH
DVFTQENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
TYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASNLRYKIFRYFNVAGATPNGI
CCCCCEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCC
IGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEK
HCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHH
LGWDPQYVNVKTIIEHAWNWHQKKPNGYDK
CCCCCCEEHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLR
CCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHCCHHHCCCCCCHHHHHH
DVFTQENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
TYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASNLRYKIFRYFNVAGATPNGI
CCCCCEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCC
IGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEK
HCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHH
LGWDPQYVNVKTIIEHAWNWHQKKPNGYDK
CCCCCCEEHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]