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The map label for this gene is resE [H]

Identifier: 118480300

GI number: 118480300

Start: 5014337

End: 5015785

Strand: Reverse

Name: resE [H]

Synonym: BALH_4761

Alternate gene names: 118480300

Gene position: 5015785-5014337 (Counterclockwise)

Preceding gene: 118480301

Following gene: 118480299

Centisome position: 95.41

GC content: 38.51

Gene sequence:

>1449_bases
TTGTTAAGTGGTGATGGTATGTCTTTGAAAAGAAATATGGTGTTTGGAATCGTTGGACTGTTAATCCCGATTTTTGTTCT
TTTGTATGCAGTTGTTTATATTACGTTAGAAAAGAATATGTATCATAACGCTGCAGATTCTTTAGAAAAGTTAAGTGTAG
AAGCACAAATTTACACGATGAATTATTTAGAGAAGGAAGCAGAGGTAGAGACGCTCGGTCCGAATTCACTTTTAATTGCT
TCGTATTTAGCGAAGCGCATGGATGTCCGTGTACAGATGATTGGGAAGAATGGAGATGTTGTTGCGGATACGCAAAAGGG
AGCACTTCTTCATCGGAATATTGATATTGAGAGCTCTTTGAAAGGGAAGAAATCTTATGTTTTTGAAGAGGGAGACCCGG
CTCCAATTCTTTTGTTTTCAAGCCCGGTTTATTATGGAAACGATGTCATTGGAAGTGTTCGTTTTATAAATGAGTTAACG
GGTGAGAAGGAAGTTTTAACAAATGTCGGTTGGACGTTCTTAATGACGTCTCTTTGTCTCGTAGCTGCGGGTATTTTCTT
TGCAATTCGTTTGGCAAAGTCTCTCCATAAGCCGATTGATCAGTTAAGACAAATGGCACACCGGCTTGCGAATGGTGATT
ATAAAAGTAAGATTGAGCTAAATGAATATGTGGAAATTGCTCAGCTTTCCGCATCTTTTAATGCAATGGCCGATGGAATT
GAACTGCATATTAAGCAATTGAAGGAAGAGAAAGAGAAGCAGAAAGATTTCTTAGACCGCATTACGCATGAGCTGAAAAC
ACCGCTAACGGCGATTATTGGCTATGTGGATTTAATTCCGAAGTTAAAGGCGAAGGAAGATATACAGGAGAGCTTGCGTT
ATGTGGCTGTAGAAAGCGAGCGTTTATTGTCACTTGTAGAGGAATTACTTCAGTCTTCAAAGTACGGAACGAGTACGTTT
GAAATATCACCTACAGTTGTGAATATAAAGGAATTGGCTGAAGAAGCAGTTTCAATTGTGAAACCTCGCCTGCAGAAATT
TGAGATTGAAGTTATCAATGAGTTAACAGATGTACATGTTGTTGCAGATTTCGATAAGACGAAACAGATCTTCTTAAATG
TGCTTGATAATGCGATAAAATATAGCGATGCTACGCAAATTCGTATGAATGTAATTATAAATGAACGTGAGGCAAAAGTT
TTTGTTCATGATGATGGCATTGGTATAGATGAAGGTGTGCTAGCAGAGTGGAATGAATCGCCAAAAGGGAAGGTTCTTCC
TTCTAGTTACGGGAATGGTTACGGTTTGTATATTTGTCAGGAGATTATGGATAAGCAGGGCGGAAGTATGCGGATTGAGA
GTAGTGAAGAAATAGGCACTACCATATTTATTACATTCTTGCTTCCGAGAAGGATGGAAGATATAAAAAATCTGAAAGCG
GTTAAATGA

Upstream 100 bases:

>100_bases
ATACGAGAGCGGTTGATATTATGGTGCAAAGATTGCGGAAGAAGTTAGGGAATAGCGGGGAATATATTAAGACAATTTAT
GGCGTTGGCTATAAACTGGA

Downstream 100 bases:

>100_bases
TACATTTATGAAACAATTATGCGGTATTTTCGAAACAACGTTTTTTTATCTTGGAGGTAGGCAGAAATGAAAAGGCTATC
ATTTCAAATTCTTATGTTTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MLSGDGMSLKRNMVFGIVGLLIPIFVLLYAVVYITLEKNMYHNAADSLEKLSVEAQIYTMNYLEKEAEVETLGPNSLLIA
SYLAKRMDVRVQMIGKNGDVVADTQKGALLHRNIDIESSLKGKKSYVFEEGDPAPILLFSSPVYYGNDVIGSVRFINELT
GEKEVLTNVGWTFLMTSLCLVAAGIFFAIRLAKSLHKPIDQLRQMAHRLANGDYKSKIELNEYVEIAQLSASFNAMADGI
ELHIKQLKEEKEKQKDFLDRITHELKTPLTAIIGYVDLIPKLKAKEDIQESLRYVAVESERLLSLVEELLQSSKYGTSTF
EISPTVVNIKELAEEAVSIVKPRLQKFEIEVINELTDVHVVADFDKTKQIFLNVLDNAIKYSDATQIRMNVIINEREAKV
FVHDDGIGIDEGVLAEWNESPKGKVLPSSYGNGYGLYICQEIMDKQGGSMRIESSEEIGTTIFITFLLPRRMEDIKNLKA
VK

Sequences:

>Translated_482_residues
MLSGDGMSLKRNMVFGIVGLLIPIFVLLYAVVYITLEKNMYHNAADSLEKLSVEAQIYTMNYLEKEAEVETLGPNSLLIA
SYLAKRMDVRVQMIGKNGDVVADTQKGALLHRNIDIESSLKGKKSYVFEEGDPAPILLFSSPVYYGNDVIGSVRFINELT
GEKEVLTNVGWTFLMTSLCLVAAGIFFAIRLAKSLHKPIDQLRQMAHRLANGDYKSKIELNEYVEIAQLSASFNAMADGI
ELHIKQLKEEKEKQKDFLDRITHELKTPLTAIIGYVDLIPKLKAKEDIQESLRYVAVESERLLSLVEELLQSSKYGTSTF
EISPTVVNIKELAEEAVSIVKPRLQKFEIEVINELTDVHVVADFDKTKQIFLNVLDNAIKYSDATQIRMNVIINEREAKV
FVHDDGIGIDEGVLAEWNESPKGKVLPSSYGNGYGLYICQEIMDKQGGSMRIESSEEIGTTIFITFLLPRRMEDIKNLKA
VK
>Mature_482_residues
MLSGDGMSLKRNMVFGIVGLLIPIFVLLYAVVYITLEKNMYHNAADSLEKLSVEAQIYTMNYLEKEAEVETLGPNSLLIA
SYLAKRMDVRVQMIGKNGDVVADTQKGALLHRNIDIESSLKGKKSYVFEEGDPAPILLFSSPVYYGNDVIGSVRFINELT
GEKEVLTNVGWTFLMTSLCLVAAGIFFAIRLAKSLHKPIDQLRQMAHRLANGDYKSKIELNEYVEIAQLSASFNAMADGI
ELHIKQLKEEKEKQKDFLDRITHELKTPLTAIIGYVDLIPKLKAKEDIQESLRYVAVESERLLSLVEELLQSSKYGTSTF
EISPTVVNIKELAEEAVSIVKPRLQKFEIEVINELTDVHVVADFDKTKQIFLNVLDNAIKYSDATQIRMNVIINEREAKV
FVHDDGIGIDEGVLAEWNESPKGKVLPSSYGNGYGLYICQEIMDKQGGSMRIESSEEIGTTIFITFLLPRRMEDIKNLKA
VK

Specific function: Could be member of the two-component regulatory system yclK/yclJ. Potentially phosphorylates yclJ [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=286, Percent_Identity=24.1258741258741, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=25.5952380952381, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789149, Length=338, Percent_Identity=22.4852071005917, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788713, Length=273, Percent_Identity=24.9084249084249, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788549, Length=213, Percent_Identity=27.6995305164319, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=24.5535714285714, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=272, Percent_Identity=23.1617647058824, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790861, Length=386, Percent_Identity=22.279792746114, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=24.1379310344828, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=23.4567901234568, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54159; Mature: 54159

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGDGMSLKRNMVFGIVGLLIPIFVLLYAVVYITLEKNMYHNAADSLEKLSVEAQIYTM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEEH
NYLEKEAEVETLGPNSLLIASYLAKRMDVRVQMIGKNGDVVADTQKGALLHRNIDIESSL
HHHHHHCCCEECCCCHHHHHHHHHHHHCEEEEEECCCCCEEEECCCCEEEEECCCCHHCC
KGKKSYVFEEGDPAPILLFSSPVYYGNDVIGSVRFINELTGEKEVLTNVGWTFLMTSLCL
CCCCCEEEECCCCCEEEEEECCCEECCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHH
VAAGIFFAIRLAKSLHKPIDQLRQMAHRLANGDYKSKIELNEYVEIAQLSASFNAMADGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHH
ELHIKQLKEEKEKQKDFLDRITHELKTPLTAIIGYVDLIPKLKAKEDIQESLRYVAVESE
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHH
RLLSLVEELLQSSKYGTSTFEISPTVVNIKELAEEAVSIVKPRLQKFEIEVINELTDVHV
HHHHHHHHHHHCCCCCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VADFDKTKQIFLNVLDNAIKYSDATQIRMNVIINEREAKVFVHDDGIGIDEGVLAEWNES
EECCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCC
PKGKVLPSSYGNGYGLYICQEIMDKQGGSMRIESSEEIGTTIFITFLLPRRMEDIKNLKA
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEHHHHHHHHHHHHHCC
VK
CC
>Mature Secondary Structure
MLSGDGMSLKRNMVFGIVGLLIPIFVLLYAVVYITLEKNMYHNAADSLEKLSVEAQIYTM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEEH
NYLEKEAEVETLGPNSLLIASYLAKRMDVRVQMIGKNGDVVADTQKGALLHRNIDIESSL
HHHHHHCCCEECCCCHHHHHHHHHHHHCEEEEEECCCCCEEEECCCCEEEEECCCCHHCC
KGKKSYVFEEGDPAPILLFSSPVYYGNDVIGSVRFINELTGEKEVLTNVGWTFLMTSLCL
CCCCCEEEECCCCCEEEEEECCCEECCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHH
VAAGIFFAIRLAKSLHKPIDQLRQMAHRLANGDYKSKIELNEYVEIAQLSASFNAMADGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHH
ELHIKQLKEEKEKQKDFLDRITHELKTPLTAIIGYVDLIPKLKAKEDIQESLRYVAVESE
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHH
RLLSLVEELLQSSKYGTSTFEISPTVVNIKELAEEAVSIVKPRLQKFEIEVINELTDVHV
HHHHHHHHHHHCCCCCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VADFDKTKQIFLNVLDNAIKYSDATQIRMNVIINEREAKVFVHDDGIGIDEGVLAEWNES
EECCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCC
PKGKVLPSSYGNGYGLYICQEIMDKQGGSMRIESSEEIGTTIFITFLLPRRMEDIKNLKA
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEHHHHHHHHHHHHHCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]