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The map label for this gene is lytF [H]

Identifier: 118480231

GI number: 118480231

Start: 4930956

End: 4932266

Strand: Reverse

Name: lytF [H]

Synonym: BALH_4689

Alternate gene names: 118480231

Gene position: 4932266-4930956 (Counterclockwise)

Preceding gene: 118480232

Following gene: 118480230

Centisome position: 93.82

GC content: 37.3

Gene sequence:

>1311_bases
ATGAAAAAGCTAAAAATGGCATCTTGCGCATTAGTTGCAGGGTTAATGTTTTCAGGGCTAACACCAAATGCATTTGCAGA
AGATAAAATTTCTGACGTGAAATCACAAATTAATACACAAAATGACACTTTACATAAACAACAACAAGAGCGTGATGAAT
TACAAAAACAAATGAATGACTTAAACAAAACAATTCAAGGTTTAGATAAGTCTGTTCAAGAGAATGCTGCAAAACTTGAT
GAAACAACGAAAAAAGTCGCGGATACTGAGCAATTAATTGAAAAGAAAAATAAAGATATTGCAGAATTACAAACGAAAAT
TGCAAAACGTGAAGAGTTATTAAGAAAACGTTTAGTTGCACTTCAAGAGCAACCAAACACGAACGTTGTAACAGAAGTTC
TTGTAAACTCTAAAAACGTTGCAGATTTAGTTGATCGTTTAACTTCTGTTTCTAAAATTCTTGAGTCTGACGAAGATATC
ATGAAAACACAACAAGAAGATCAAGCGAACGTGAAAAAAGATGTTGAAACAGTAAAAACGAAGCAAAAAGAATTAAAAGA
AGCACAAGCTCAAATTGAAACTGCTAAGAAAGAACTTGACGCTGAAAAAGCGAAAAAAGCAACAGCAGTAAACGATTTAA
GCGGTAAAATGGATACAGTTGTAACTTCAATGACAAGTACGGAAAGTCAATTGAAAGATCTTGAAAAGCAAGCGTTACAA
TTACAACGTATTGCTGAACAAGAAGCGCAAGAAAAAGCTGCACAAGAAGCTGCTGCTCAAAAACAAGCAGAGCAAGCTGC
TAAAGATGCGCAAGCTCAGCAAGCACAAGCGGCACCTGCTCAGCCAGCAGCGCCAGCAAACAACGGTGGACAAGCTCAAA
AAGAAGCACCTAAAAAAGAAGAGCCTAAAAAAGAAGTACCTAAAAAAGAAGATAAAAAACCAGAACCGACACCAGGTCCA
GCTCCGGCTCCTGGCGTAATTGGTAAAGCACAACAATACTTAGGTTTACCATATGTTTGGGGAAGTGCATCTCCATCAAA
CGGTGGTTTTGACTGTAGTGGATTTATTTCTTACATCTTTGGTGTAGGTCGTCAAGACGTTGCAGGTTACTGGAACTCAG
TTTCTAAAGTAAGTAGCCCACAACCTGGAGACTTAGTATTCTTCCAAGGTACTTATAAACCAGGTCCATCTCACATCGGT
ATTTATGTTGGTAATGGTCAAATGATTCATGCTGGTGATAAAGGTATTGCTTACTCTAGCTTAAGCAGTAGCTACAATCA
AAAACATTTCTTAGGATACGGTAGATTCTAG

Upstream 100 bases:

>100_bases
TACAAAAGCGTAACATTAGCAAAAAAAATCCCGAATTATGGTATAAATTTTATAGGTTATATACGGAAAAAAGAAAAAAG
AAAGCGGTGTAAAAAATAAA

Downstream 100 bases:

>100_bases
GATTTATAATCGAATAAAACATGTGTATAAAGTCGATAGCTTACTATTTTATAAGTAGGTTATCGGCTTTTTTGAGTTTT
TACGAGATTATAAGAAAGGT

Product: endopeptidase LytE

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP49; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MKKLKMASCALVAGLMFSGLTPNAFAEDKISDVKSQINTQNDTLHKQQQERDELQKQMNDLNKTIQGLDKSVQENAAKLD
ETTKKVADTEQLIEKKNKDIAELQTKIAKREELLRKRLVALQEQPNTNVVTEVLVNSKNVADLVDRLTSVSKILESDEDI
MKTQQEDQANVKKDVETVKTKQKELKEAQAQIETAKKELDAEKAKKATAVNDLSGKMDTVVTSMTSTESQLKDLEKQALQ
LQRIAEQEAQEKAAQEAAAQKQAEQAAKDAQAQQAQAAPAQPAAPANNGGQAQKEAPKKEEPKKEVPKKEDKKPEPTPGP
APAPGVIGKAQQYLGLPYVWGSASPSNGGFDCSGFISYIFGVGRQDVAGYWNSVSKVSSPQPGDLVFFQGTYKPGPSHIG
IYVGNGQMIHAGDKGIAYSSLSSSYNQKHFLGYGRF

Sequences:

>Translated_436_residues
MKKLKMASCALVAGLMFSGLTPNAFAEDKISDVKSQINTQNDTLHKQQQERDELQKQMNDLNKTIQGLDKSVQENAAKLD
ETTKKVADTEQLIEKKNKDIAELQTKIAKREELLRKRLVALQEQPNTNVVTEVLVNSKNVADLVDRLTSVSKILESDEDI
MKTQQEDQANVKKDVETVKTKQKELKEAQAQIETAKKELDAEKAKKATAVNDLSGKMDTVVTSMTSTESQLKDLEKQALQ
LQRIAEQEAQEKAAQEAAAQKQAEQAAKDAQAQQAQAAPAQPAAPANNGGQAQKEAPKKEEPKKEVPKKEDKKPEPTPGP
APAPGVIGKAQQYLGLPYVWGSASPSNGGFDCSGFISYIFGVGRQDVAGYWNSVSKVSSPQPGDLVFFQGTYKPGPSHIG
IYVGNGQMIHAGDKGIAYSSLSSSYNQKHFLGYGRF
>Mature_436_residues
MKKLKMASCALVAGLMFSGLTPNAFAEDKISDVKSQINTQNDTLHKQQQERDELQKQMNDLNKTIQGLDKSVQENAAKLD
ETTKKVADTEQLIEKKNKDIAELQTKIAKREELLRKRLVALQEQPNTNVVTEVLVNSKNVADLVDRLTSVSKILESDEDI
MKTQQEDQANVKKDVETVKTKQKELKEAQAQIETAKKELDAEKAKKATAVNDLSGKMDTVVTSMTSTESQLKDLEKQALQ
LQRIAEQEAQEKAAQEAAAQKQAEQAAKDAQAQQAQAAPAQPAAPANNGGQAQKEAPKKEEPKKEVPKKEDKKPEPTPGP
APAPGVIGKAQQYLGLPYVWGSASPSNGGFDCSGFISYIFGVGRQDVAGYWNSVSKVSSPQPGDLVFFQGTYKPGPSHIG
IYVGNGQMIHAGDKGIAYSSLSSSYNQKHFLGYGRF

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=120, Percent_Identity=35, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786421, Length=117, Percent_Identity=34.1880341880342, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 47584; Mature: 47584

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKMASCALVAGLMFSGLTPNAFAEDKISDVKSQINTQNDTLHKQQQERDELQKQMND
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LNKTIQGLDKSVQENAAKLDETTKKVADTEQLIEKKNKDIAELQTKIAKREELLRKRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LQEQPNTNVVTEVLVNSKNVADLVDRLTSVSKILESDEDIMKTQQEDQANVKKDVETVKT
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KQKELKEAQAQIETAKKELDAEKAKKATAVNDLSGKMDTVVTSMTSTESQLKDLEKQALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQRIAEQEAQEKAAQEAAAQKQAEQAAKDAQAQQAQAAPAQPAAPANNGGQAQKEAPKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCC
EPKKEVPKKEDKKPEPTPGPAPAPGVIGKAQQYLGLPYVWGSASPSNGGFDCSGFISYIF
CCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHH
GVGRQDVAGYWNSVSKVSSPQPGDLVFFQGTYKPGPSHIGIYVGNGQMIHAGDKGIAYSS
HCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEECCCEEEECCCCCCCHHH
LSSSYNQKHFLGYGRF
HHHCCCCHHCCCCCCC
>Mature Secondary Structure
MKKLKMASCALVAGLMFSGLTPNAFAEDKISDVKSQINTQNDTLHKQQQERDELQKQMND
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LNKTIQGLDKSVQENAAKLDETTKKVADTEQLIEKKNKDIAELQTKIAKREELLRKRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LQEQPNTNVVTEVLVNSKNVADLVDRLTSVSKILESDEDIMKTQQEDQANVKKDVETVKT
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KQKELKEAQAQIETAKKELDAEKAKKATAVNDLSGKMDTVVTSMTSTESQLKDLEKQALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQRIAEQEAQEKAAQEAAAQKQAEQAAKDAQAQQAQAAPAQPAAPANNGGQAQKEAPKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCC
EPKKEVPKKEDKKPEPTPGPAPAPGVIGKAQQYLGLPYVWGSASPSNGGFDCSGFISYIF
CCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHH
GVGRQDVAGYWNSVSKVSSPQPGDLVFFQGTYKPGPSHIGIYVGNGQMIHAGDKGIAYSS
HCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEECCCEEEECCCCCCCHHH
LSSSYNQKHFLGYGRF
HHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10206711 [H]