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The map label for this gene is kapD [H]

Identifier: 118480004

GI number: 118480004

Start: 4685235

End: 4685858

Strand: Reverse

Name: kapD [H]

Synonym: BALH_4451

Alternate gene names: 118480004

Gene position: 4685858-4685235 (Counterclockwise)

Preceding gene: 118480008

Following gene: 118480002

Centisome position: 89.13

GC content: 37.34

Gene sequence:

>624_bases
ATGGATGAACAACGATTTTTATTTTTGGATTTTGAGTTTACGATGCCCCAGCACAGAAAAAAACCAAAAGGATTTTTCCC
GGAGATTATTGAGGTAGGACTCGTTTCGGTTGTTGGCTGTAAGGTAGAAGATACGTATTCAGCTCATGTGAGGCCGAAAA
CTTTTCCTTCTTTAACGGATCGATGTAAGAAATTTTTAGGGATTAAACAAGAAGTCGTAGATAAAGGGATTTCGTTTCTA
GAACTCGTTGAAAAACTCGCAGAATATGAAAAGAAATGTAAACCGACCATTGTTACGTGGGGAAATATGGATATGAAAGT
GTTGAAGCATAATTGTGAAAAAGCGGAGGTAGATTTTCCGTTCCTAGGACAGTGCCGTGATTTATCACTTGAGTATAAGA
AGTTTTTTGGTGAGAGAAATCAAACAGGATTGTGGAAAGCAATTGAAGCGTATGGAAAAGTAGGGACGGGTAAGCATCAT
TGTGCGCTAGATGATGCGATGACGACGTATAATATTTTTAAATTAGTAGAAAAAGATAAAGAGTATTTAGTGAAACCAGC
ACCTCCAACATTAGGCGAACTCGTTGATTTTTCAAAAGTGTTAAAGAAAGTGAGCACACAGTAA

Upstream 100 bases:

>100_bases
ACATCCAATCTGAATATTTAAAATGGAATTAGCATTCGAGCTTGTTCGTGTAGGAGTGTCAAATAGAAAGGAATGACAAA
GATGATAAGGAAGGGATCGT

Downstream 100 bases:

>100_bases
CGACCAAATTGCACAGTATGTAATTTGGTCGTTTTGTTTTTTTAAAGTTTGTAGTCTTTTTTTAACTGCTCTAATGTTTC
TAGACTACGAACCGCAAAAG

Product: sporulation inhibitor KapD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTDRCKKFLGIKQEVVDKGISFL
ELVEKLAEYEKKCKPTIVTWGNMDMKVLKHNCEKAEVDFPFLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHH
CALDDAMTTYNIFKLVEKDKEYLVKPAPPTLGELVDFSKVLKKVSTQ

Sequences:

>Translated_207_residues
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTDRCKKFLGIKQEVVDKGISFL
ELVEKLAEYEKKCKPTIVTWGNMDMKVLKHNCEKAEVDFPFLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHH
CALDDAMTTYNIFKLVEKDKEYLVKPAPPTLGELVDFSKVLKKVSTQ
>Mature_207_residues
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTDRCKKFLGIKQEVVDKGISFL
ELVEKLAEYEKKCKPTIVTWGNMDMKVLKHNCEKAEVDFPFLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHH
CALDDAMTTYNIFKLVEKDKEYLVKPAPPTLGELVDFSKVLKKVSTQ

Specific function: Specifically inhibits the kinA pathway to sporulation [H]

COG id: COG5018

COG function: function code R; Inhibitor of the KinA pathway to sporulation, predicted exonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI31543184, Length=176, Percent_Identity=31.25, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: NA

Molecular weight: Translated: 23825; Mature: 23825

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTD
CCCCEEEEEEEEECCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
RCKKFLGIKQEVVDKGISFLELVEKLAEYEKKCKPTIVTWGNMDMKVLKHNCEKAEVDFP
HHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCCCC
FLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHHCALDDAMTTYNIFKLVEKDK
CCCCHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EYLVKPAPPTLGELVDFSKVLKKVSTQ
HHEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDEQRFLFLDFEFTMPQHRKKPKGFFPEIIEVGLVSVVGCKVEDTYSAHVRPKTFPSLTD
CCCCEEEEEEEEECCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
RCKKFLGIKQEVVDKGISFLELVEKLAEYEKKCKPTIVTWGNMDMKVLKHNCEKAEVDFP
HHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCCCC
FLGQCRDLSLEYKKFFGERNQTGLWKAIEAYGKVGTGKHHCALDDAMTTYNIFKLVEKDK
CCCCHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EYLVKPAPPTLGELVDFSKVLKKVSTQ
HHEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]