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The map label for this gene is yqeV [H]

Identifier: 118479478

GI number: 118479478

Start: 4110004

End: 4111356

Strand: Reverse

Name: yqeV [H]

Synonym: BALH_3900

Alternate gene names: 118479478

Gene position: 4111356-4110004 (Counterclockwise)

Preceding gene: 118479479

Following gene: 118479477

Centisome position: 78.21

GC content: 37.47

Gene sequence:

>1353_bases
ATGTCAACTGTTGCGTTCCATACGTTAGGTTGTAAAGTAAACCACTATGAAACAGAAGCCATTTGGCAATTGTTTAAACA
AGGTGGATATGAAAGAACGGAATATGAAAAGAAAGCTGATGTATATGTTATTAATACATGTACAGTAACAAATACGGGAG
ATAAGAAAAGTCGTCAAGTTATTAGACGTGCTGTTCGTCAAAACCCAGATGCAGTTATTTGTGTAACAGGATGTTATGCA
CAAACATCTCCAGCGGAAATTATGGCGATTCCAGGTGTAGATATTGTAGTTGGTACACAAGATCGTGAAAAGATGCTAGG
ATACATCGAAGAATTCCGTAAAGAGCGTCAACCAATTAATGCTGTCCGTAACATTATGAAAACACGTGTATACGAAGAAC
TGGATGTACCTTATTTTACGGATCGTACACGTGCATCTTTAAAAATACAAGAAGGTTGTAATAACTTCTGTACATTCTGT
ATTATTCCTTGGGCGCGTGGTTTAATGCGTTCTCGTGATGGGAAAGAAGTTATTAAACAAGCGCAACAATTAGTAGATGC
AGGTTATAAAGAAATCGTATTAACAGGTATTCATACAGGTGGGTACGGTGAAGATATTAAAGATTATAACTTAGCTGGAT
TACTTCGTGATATGGAAGCAGAAGTAGGCGGATTAAAACGTCTTCGTATTTCTTCTATTGAAGCGAGTCAGATTTCAGAT
GAAGTAATTGAAGTGTTAGATAAGTCTGAAGTAGTTGTACGTCACTTACACATTCCGTTGCAATCTGGATCTAATACTGT
ATTAAAGCGTATGCGTCGTAAGTATACGATGGAATTCTTCCAAGAGCGTTTAGATCGTTTGAAAGAAGCGTTACCAGGTC
TTGCGATTACATCAGACGTAATCGTTGGTTTCCCAGGTGAAACAGAAGAAGAATTCATGGAAACATACAATTTCATTAAA
GAGAACCGCTTCTCTGAGTTACACGTGTTCCCTTACTCGAAACGTACAGGAACACCTGCAGCACGCATGGAAGACCAAGT
TCCTGAAGATGTAAAGAACGATCGTGTTCACCGTTTAATTGAATTATCTAATCAATTAGCGAAAGAGTATGCATCACAGT
TTGAAGGAGAAGTACTTGAAATTATTCCAGAAGAACAATTTAAAGAGGGCGACCGTGAAGGCCTATATGTAGGTTATACA
GATAACTACTTGAAAATTGTATTTGAAGGATCAGAAGAATTAATTGGTAAACTAGTGAAAGTGAAAATCACGAAAGCTGG
TTATCCATATAACGAAGCGCAATTTGCTCGTGTTCTTGAAGATGATGTAAAAAAGGAATCAGCAAGCGCATAA

Upstream 100 bases:

>100_bases
ACCATGTAGTTTAGGACCAAGAATTTTAAGAACAGAAACGGCGCCGTTATACGCGTTAAGTGCTGCTTCGTATCATTTTG
AATTGATGGGGTGATGATCA

Downstream 100 bases:

>100_bases
AAAAAAGCATGCAAACGGAAACGATTTGCATGCTTTCTTTTTTTGTGGAGAAGTTAAGTACTGAAAATGTACAAGATGCG
TAGTTGTTTCGTACGTTCCT

Product: 2-methylthioadenine synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSTVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQVIRRAVRQNPDAVICVTGCYA
QTSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPINAVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFC
IIPWARGLMRSRDGKEVIKQAQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISD
EVIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDVIVGFPGETEEEFMETYNFIK
ENRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLIELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYT
DNYLKIVFEGSEELIGKLVKVKITKAGYPYNEAQFARVLEDDVKKESASA

Sequences:

>Translated_450_residues
MSTVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQVIRRAVRQNPDAVICVTGCYA
QTSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPINAVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFC
IIPWARGLMRSRDGKEVIKQAQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISD
EVIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDVIVGFPGETEEEFMETYNFIK
ENRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLIELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYT
DNYLKIVFEGSEELIGKLVKVKITKAGYPYNEAQFARVLEDDVKKESASA
>Mature_449_residues
STVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQVIRRAVRQNPDAVICVTGCYAQ
TSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPINAVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFCI
IPWARGLMRSRDGKEVIKQAQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISDE
VIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDVIVGFPGETEEEFMETYNFIKE
NRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLIELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYTD
NYLKIVFEGSEELIGKLVKVKITKAGYPYNEAQFARVLEDDVKKESASA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=441, Percent_Identity=30.8390022675737, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI28872784, Length=444, Percent_Identity=28.1531531531532, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI28872782, Length=444, Percent_Identity=28.1531531531532, Blast_Score=181, Evalue=9e-46,
Organism=Escherichia coli, GI1786882, Length=430, Percent_Identity=33.2558139534884, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1787057, Length=395, Percent_Identity=32.1518987341772, Blast_Score=187, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17553146, Length=468, Percent_Identity=27.5641025641026, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71996771, Length=275, Percent_Identity=31.6363636363636, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21356207, Length=441, Percent_Identity=28.5714285714286, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI19922432, Length=431, Percent_Identity=30.8584686774942, Blast_Score=180, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 51400; Mature: 51269

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQV
CCCEEEEEECCEECCCHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEEECCCCCHHHHHH
IRRAVRQNPDAVICVTGCYAQTSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPIN
HHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCHHH
AVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDGKEVIKQ
HHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
AQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISD
HHHHHHCCCHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHEEECCCCHHHHHH
EVIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDV
HHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCE
IVGFPGETEEEFMETYNFIKENRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLI
EEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHH
ELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYTDNYLKIVFEGSEELIGKLVK
HHHHHHHHHHHHHHCCCCEEECCCHHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHH
VKITKAGYPYNEAQFARVLEDDVKKESASA
EEEECCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STVAFHTLGCKVNHYETEAIWQLFKQGGYERTEYEKKADVYVINTCTVTNTGDKKSRQV
CCEEEEEECCEECCCHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEEECCCCCHHHHHH
IRRAVRQNPDAVICVTGCYAQTSPAEIMAIPGVDIVVGTQDREKMLGYIEEFRKERQPIN
HHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCHHH
AVRNIMKTRVYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDGKEVIKQ
HHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
AQQLVDAGYKEIVLTGIHTGGYGEDIKDYNLAGLLRDMEAEVGGLKRLRISSIEASQISD
HHHHHHCCCHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHEEECCCCHHHHHH
EVIEVLDKSEVVVRHLHIPLQSGSNTVLKRMRRKYTMEFFQERLDRLKEALPGLAITSDV
HHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCE
IVGFPGETEEEFMETYNFIKENRFSELHVFPYSKRTGTPAARMEDQVPEDVKNDRVHRLI
EEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHH
ELSNQLAKEYASQFEGEVLEIIPEEQFKEGDREGLYVGYTDNYLKIVFEGSEELIGKLVK
HHHHHHHHHHHHHHCCCCEEECCCHHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHH
VKITKAGYPYNEAQFARVLEDDVKKESASA
EEEECCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]