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The map label for this gene is nagA [H]

Identifier: 118479259

GI number: 118479259

Start: 3896020

End: 3897168

Strand: Reverse

Name: nagA [H]

Synonym: BALH_3671

Alternate gene names: 118479259

Gene position: 3897168-3896020 (Counterclockwise)

Preceding gene: 118479260

Following gene: 118479258

Centisome position: 74.13

GC content: 37.34

Gene sequence:

>1149_bases
ATGAAAATGAAAACGCAAGTTGTCATCAATGCCAAAATTTATACAGGTCAAGAAGTAGTAGAAAACGGATTTATTCGTTA
CGCAGAAACAATTAAAGAAATTGGTTTGATGGCTCAATATGTATCACAAGAAAATGAAACTGTTTTAGATGCAGCAGGGA
AGATTGTGATTCCAGGTATGATTGATGTTCATATTCATGGTGGATACGATATTGATGCGATGGATGCAAATAGCGATGGG
TTAGTAACTCTAGGGAAAGAAATGTTAAAAGAAGGAGTTACAACTTACTTCCCAACAACAATGACACAAGCTCCAGAAGC
AATCGAAGCAGCACTACATGCTGCGAAGGAAGCGAAAGAAAAAGGAGCACATTTCGAATATATTCACTTAGAAGGACCGT
ATGTTTCAAAAAAACGTGCAGGTGCACAACCACTTGAACATATTGTTCCTGCTAATATTGAACAATTTAAACAATGGCAG
GAAGCAAGCGGAAATCTAATTAAATTAGTAACATACGCACCTGAAGAAGAAGGAGCATTAGAGTTTGAGCAGTATCTTGC
TGAAACTGGTGTTGTCGGCACAATGGGGCATACAGATGCAATTGATGCGCAACTAAAAAACAGAAACATTACACATGCAA
CGCATTTATACAATCAAATGCGTGGATTACATCACCGTGAACCAGGAGTTGTTGGTCATGTGTTATTAAATCCAGATGTA
ATGGTTGAAGTAATTACAGATGGTATTCACATTCACCCTGATATGGTGAAATTAGCATATAAATTAAAAGGACCGAAAAA
AGTAAGTGTTATTACTGACGCAATGCGTGCAAAAGGTCTTGAAGATGGATTATATGAGCTTGGCGGACAGCCAGTACATG
TAAAAGATGGTAGTGCTCGATTAGAAGATGGAACGCTAGCTGGTAGTATTCTAAAAATGGATCAAGCTTTCCGAAATGTA
ATTGAATTTACAGGTTGTTCAATCGAAGATGCAGTACTGATGACATCAGTTAACCAAGCAGAAGAGTTTGGATTAAATAA
TAAAGGTGCGTTAGCGGTAGGAAAAGATGCAGACTTTGTTGTGATGAATGAAGATTTACATGTATATGATACGGTTCGTT
TAGGAATTCATATGAAGGAAGGGAAGTAA

Upstream 100 bases:

>100_bases
ATTTCATTAGAATGTATAGACAACTACTCGTGCATATATTAAGATGGAATTAGGCGAATAAGGTAATAATAACAAGTAGG
TATTTCATGGGAAAGGATCG

Downstream 100 bases:

>100_bases
TTAAATGAATATTCTTGTTGTAAAAACTCCAGAAGAACTAGCAGAAGCAGGTTATAAATTAATTGAAGAAGTTGTAAAAA
CAAAAGAAAATCCAACATTA

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKMKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGMIDVHIHGGYDIDAMDANSDG
LVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQ
EASGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDV
MVEVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNV
IEFTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK

Sequences:

>Translated_382_residues
MKMKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGMIDVHIHGGYDIDAMDANSDG
LVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQ
EASGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDV
MVEVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNV
IEFTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK
>Mature_382_residues
MKMKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGMIDVHIHGGYDIDAMDANSDG
LVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQ
EASGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDV
MVEVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNV
IEFTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=416, Percent_Identity=31.0096153846154, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI224922791, Length=416, Percent_Identity=31.0096153846154, Blast_Score=175, Evalue=5e-44,
Organism=Escherichia coli, GI1786892, Length=371, Percent_Identity=28.8409703504043, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17553768, Length=349, Percent_Identity=35.243553008596, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI19920392, Length=345, Percent_Identity=34.2028985507246, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281361140, Length=359, Percent_Identity=32.8690807799443, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41871; Mature: 41871

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGM
CCCEEEEEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCE
IDVHIHGGYDIDAMDANSDGLVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKE
EEEEEECCCEEEEECCCCCCEEHHHHHHHHCCCCEECCCHHHCCHHHHHHHHHHHHHHHH
KGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEASGNLIKLVTYAPEEEGAL
CCCCEEEEEECCCCCCHHHCCCCCHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCH
EFEQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDV
HHHHHHHHCCCEECCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCE
MVEVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSAR
EEEEECCCEEECHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCC
LEDGTLAGSILKMDQAFRNVIEFTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHCCCCCCCCEEECCCCCEE
VMNEDLHVYDTVRLGIHMKEGK
EECCCEEEEEEEEEEEEEECCC
>Mature Secondary Structure
MKMKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGM
CCCEEEEEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCE
IDVHIHGGYDIDAMDANSDGLVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKE
EEEEEECCCEEEEECCCCCCEEHHHHHHHHCCCCEECCCHHHCCHHHHHHHHHHHHHHHH
KGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEASGNLIKLVTYAPEEEGAL
CCCCEEEEEECCCCCCHHHCCCCCHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCH
EFEQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDV
HHHHHHHHCCCEECCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCE
MVEVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSAR
EEEEECCCEEECHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCC
LEDGTLAGSILKMDQAFRNVIEFTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHCCCCCCCCEEECCCCCEE
VMNEDLHVYDTVRLGIHMKEGK
EECCCEEEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]