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The map label for this gene is mtnD

Identifier: 118479244

GI number: 118479244

Start: 3881972

End: 3882484

Strand: Direct

Name: mtnD

Synonym: BALH_3656

Alternate gene names: 118479244

Gene position: 3881972-3882484 (Clockwise)

Preceding gene: 118479243

Following gene: 118479245

Centisome position: 73.84

GC content: 34.7

Gene sequence:

>513_bases
ATGGCGCAAATTCGTATTCATGAAGTAAATACTCGCATTGAAAATGAAGTGGAAGTATCTAAATTTCTACAAGAGGAAGG
CGTTTTATATGAGAAATGGAATATTTCTAAACTTCCTCCTCATTTAAATGAAAATTATTCGTTAACAGATGAAAACAAGG
CTGAAATATTAGCTGTGTTTTCAAAAGAAATTGCTGATGTTTCAGTGCGCCGAGGTTATAAAGCACATGATGTAATTTCA
CTTTCAAATAGCACACCTAACCTTGACGAACTATTAATTAATTTCCAAAAAGAACACCATCATACTGATGATGAAGTTCG
CTTTATTGTTAGTGGTCATGGCATCTTTGCCATTGAAGGAAAAGATGGGACATTCTTTGACGTTGAACTTGAGCCAGGCG
ATCTCATATCTGTTCCTGAAAATGCAAGACATTATTTTACCTTGCAAGATGATCGTCAAGTTGTAGCTATTCGTATTTTT
GTTACAACTGAAGGTTGGGTTCCAATCTATTAA

Upstream 100 bases:

>100_bases
TGGGGCCGAGATAGCTTTGATGCAAAGAAAAGATTAGAAGCTTATGAGTTTTTATTCCAATTTCATATAAAACTACTATC
AATTCAAGGAGGCGTTTCTA

Downstream 100 bases:

>100_bases
GGTAGTTAGTTGAATAAAAGGTCTTGGACCCCCTTTTCCAACCTTTTATTCACTCTACATATATACATCCTCCTATGGAG
CAGGCTTATTTCAAAATATG

Product: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MAQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSVRRGYKAHDVIS
LSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIF
VTTEGWVPIY

Sequences:

>Translated_170_residues
MAQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSVRRGYKAHDVIS
LSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIF
VTTEGWVPIY
>Mature_169_residues
AQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSVRRGYKAHDVISL
SNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFV
TTEGWVPIY

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family

Homologues:

Organism=Homo sapiens, GI171460928, Length=106, Percent_Identity=31.1320754716981, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161082987, Length=106, Percent_Identity=32.0754716981132, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTND_BACAH (A0RI45)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_896395.1
- ProteinModelPortal:   A0RI45
- SMR:   A0RI45
- STRING:   A0RI45
- EnsemblBacteria:   EBBACT00000067940
- GeneID:   4544749
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_3656
- NMPDR:   fig|412694.5.peg.3518
- eggNOG:   COG1791
- GeneTree:   EBGT00050000002186
- HOGENOM:   HBG660685
- OMA:   CEKNDLI
- ProtClustDB:   CLSK887193
- BioCyc:   BTHU412694:BALH_3656-MONOMER
- HAMAP:   MF_01682
- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR23418

Pfam domain/function: PF03079 ARD; SSF51182 RmlC_like_cupin

EC number: =1.13.11.54; =1.13.11.53

Molecular weight: Translated: 19577; Mature: 19446

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVF
CCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEE
SKEIADVSVRRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEG
HHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEC
KDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
CCCCEEEEEECCCCEEECCCCCEEEEEECCCCEEEEEEEEEEECCCEECC
>Mature Secondary Structure 
AQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVF
CEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEE
SKEIADVSVRRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEG
HHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEC
KDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
CCCCEEEEEECCCCEEECCCCCEEEEEECCCCEEEEEEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA