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The map label for this gene is lspA [H]

Identifier: 118479114

GI number: 118479114

Start: 3742932

End: 3743423

Strand: Reverse

Name: lspA [H]

Synonym: BALH_3524

Alternate gene names: 118479114

Gene position: 3743423-3742932 (Counterclockwise)

Preceding gene: 118479115

Following gene: 118479113

Centisome position: 71.21

GC content: 31.91

Gene sequence:

>492_bases
TTGAGGTACACTGTCTTTGTGGGGGAAATGAAAATGATATATTATGTAATAGCGTTATTTGTCATTGCCATCGATCAAAT
ATCGAAATGGCTAATTGTAAAGAACATGGAATTGGGTACGAGCATTCCGATTATCGATAATGTATTATACATAACATCAC
ATCGAAATAGAGGAGCTGCCTGGGGCATTTTAGAAAATAAAATGTGGTTCTTCTACATTATTACAGTCGTTTTTGTAGTA
TTTATTGTATTTTATATGAAAAAATATGCGAAAACAGACAAGCTTCTAGGAATTTCATTAGGTCTAATTTTAGGCGGAGC
AATTGGCAATTTTATTGATCGTGTATTTAGACAAGAAGTAGTGGATTTCATTCACGTGTATATTTTCTCGTACAACTATC
CAGTATTCAATATAGCTGATTCAGCATTATGTATTGGTGTTGTATTAATTATTATTCAAACATTATTAGAAGGCAAGAAA
ACGAAGGAGTAA

Upstream 100 bases:

>100_bases
AATGTATGAATGTGCACAACGATATTATATTACCTTTTTTTAATTTATTTTATTCTTCTATAAAGGTTCATTGTGAAAAG
GTTGCAGCTATGCTAAAATT

Downstream 100 bases:

>100_bases
TTGAATGAGTGAAGTAGTACAAGTAACAGTTGCAGAAGAACAAAAAAATGAGCGAATTGATAAATTCGTTGCAGGAATAA
ATAATGAATGGTCACGTACA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRYTVFVGEMKMIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVV
FIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKK
TKE

Sequences:

>Translated_163_residues
MRYTVFVGEMKMIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVV
FIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKK
TKE
>Mature_163_residues
MRYTVFVGEMKMIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVV
FIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKK
TKE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=147, Percent_Identity=36.0544217687075, Blast_Score=97, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18797; Mature: 18797

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYTVFVGEMKMIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHCEEEEECCCCCCCC
WGILENKMWFFYIITVVFVVFIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEV
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKTKE
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRYTVFVGEMKMIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHCEEEEECCCCCCCC
WGILENKMWFFYIITVVFVVFIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEV
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKTKE
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA