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The map label for this gene is pepQ [H]

Identifier: 118479098

GI number: 118479098

Start: 3724312

End: 3725382

Strand: Direct

Name: pepQ [H]

Synonym: BALH_3507

Alternate gene names: 118479098

Gene position: 3724312-3725382 (Clockwise)

Preceding gene: 118479097

Following gene: 118479099

Centisome position: 70.84

GC content: 34.64

Gene sequence:

>1071_bases
ATGACTTTAAAAATTAATAAAATCCAAAATCAACTACAGAACTATGAAATTGACGGGTTACTCATTACAAAAAAAGAAAA
TCGCCAATATGCGACAGGCTTTACAGGTAGTGCTGGTGTTGTCTTAATCACTGCGGATGCAGCTGTTTTTATAACTGATT
TTCGCTATGTAGACCAAGCGAATTCACAAATAAAAAATGCTGAAATTATTATGCATAAAGGAAATTTAGAAAAAGAAATT
GCAAATCAAGTATCAAAATTAAACATTCAAAAACTTGGAATTGAAGAAAATAATATGACATTGCAACAATATAAAAACTT
ACAAAAATATGTACATACAGAAATGGTTCAAGTGTGTGAAATCATTGAAAACATTCGTCTTATTAAAGACACTCATGAAA
TAGAAACAATGAAAAAGGCAGCTAATATTGCGGACGAAGCATTTCACCACATCATTACGTTTCTAAAACCAGGAATAAGT
GAAAATGATGTACGAGATGAGTTAGAATTTTTCATGCGAAAAAAAGGGGCTACGTCCTCTTCATTCCAAATCATTGTAGC
TTCTGGCGTTCGTTCTTCACTTCCTCATGGAGTTGCATCAAATAAAATAATTGAACGAGGCGACATCGTTACATTAGATT
TCGGTGCACTTTACGACGGATATTGTTCCGATATAACACGTACTGTAGCAATTGGGGAACCATCAGAAGAGTTCAAAAAA
ATATACAATGTTGTACGCGAAGCATTAAAACGCGGGACTGAAGCAATTAAGCCTGGAGAAACTGCAAAAAGTATCGATGA
TGTAACAAGAAACTACATTACAGATTGTGGATATGGTCAATATTTTGGTCACTCTACAGGGCACGGTCTTGGCTTAGAAA
TACATGAACCTCTTCGCCTATCCCAAGAAAGTAAAGCTACATTAGAAGAAGGTATGGTTGTTACCGTTGAACCCGGTATT
TACATACCAAACTGGGGCGGTTGTAGAATTGAAGATGATATCGTCATTACAAAAGACGGATATGAAGTTATTACAAAATC
AAATCGAGAACTAATTGTTATTCCTTGTTAA

Upstream 100 bases:

>100_bases
TTCACTTCAACTTAAATATATGTAGTTCTTATCCTTTCTTCAAATATACACTTTGGCACACTATTTGCTTTATTCAATAC
TGTGAATAGGGGGAATTAAT

Downstream 100 bases:

>100_bases
AATCATGACCTTTTTTAAAAGGAGTTTTTCTCTTCACATAGAATTCTTTCTCTGGAGTCATCGTTTAAAGAGGGGGAATT
GTAATTGAACTTTGTAATCG

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTLKINKIQNQLQNYEIDGLLITKKENRQYATGFTGSAGVVLITADAAVFITDFRYVDQANSQIKNAEIIMHKGNLEKEI
ANQVSKLNIQKLGIEENNMTLQQYKNLQKYVHTEMVQVCEIIENIRLIKDTHEIETMKKAANIADEAFHHIITFLKPGIS
ENDVRDELEFFMRKKGATSSSFQIIVASGVRSSLPHGVASNKIIERGDIVTLDFGALYDGYCSDITRTVAIGEPSEEFKK
IYNVVREALKRGTEAIKPGETAKSIDDVTRNYITDCGYGQYFGHSTGHGLGLEIHEPLRLSQESKATLEEGMVVTVEPGI
YIPNWGGCRIEDDIVITKDGYEVITKSNRELIVIPC

Sequences:

>Translated_356_residues
MTLKINKIQNQLQNYEIDGLLITKKENRQYATGFTGSAGVVLITADAAVFITDFRYVDQANSQIKNAEIIMHKGNLEKEI
ANQVSKLNIQKLGIEENNMTLQQYKNLQKYVHTEMVQVCEIIENIRLIKDTHEIETMKKAANIADEAFHHIITFLKPGIS
ENDVRDELEFFMRKKGATSSSFQIIVASGVRSSLPHGVASNKIIERGDIVTLDFGALYDGYCSDITRTVAIGEPSEEFKK
IYNVVREALKRGTEAIKPGETAKSIDDVTRNYITDCGYGQYFGHSTGHGLGLEIHEPLRLSQESKATLEEGMVVTVEPGI
YIPNWGGCRIEDDIVITKDGYEVITKSNRELIVIPC
>Mature_355_residues
TLKINKIQNQLQNYEIDGLLITKKENRQYATGFTGSAGVVLITADAAVFITDFRYVDQANSQIKNAEIIMHKGNLEKEIA
NQVSKLNIQKLGIEENNMTLQQYKNLQKYVHTEMVQVCEIIENIRLIKDTHEIETMKKAANIADEAFHHIITFLKPGISE
NDVRDELEFFMRKKGATSSSFQIIVASGVRSSLPHGVASNKIIERGDIVTLDFGALYDGYCSDITRTVAIGEPSEEFKKI
YNVVREALKRGTEAIKPGETAKSIDDVTRNYITDCGYGQYFGHSTGHGLGLEIHEPLRLSQESKATLEEGMVVTVEPGIY
IPNWGGCRIEDDIVITKDGYEVITKSNRELIVIPC

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=256, Percent_Identity=30.859375, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI260593665, Length=297, Percent_Identity=26.2626262626263, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI149589008, Length=297, Percent_Identity=26.2626262626263, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI264681563, Length=227, Percent_Identity=29.5154185022026, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI93141226, Length=244, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40385867, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI164420681, Length=245, Percent_Identity=20.8163265306122, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788728, Length=351, Percent_Identity=38.1766381766382, Blast_Score=264, Evalue=8e-72,
Organism=Escherichia coli, GI1789275, Length=261, Percent_Identity=30.6513409961686, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786364, Length=229, Percent_Identity=26.2008733624454, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71989583, Length=265, Percent_Identity=25.6603773584906, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508215, Length=297, Percent_Identity=25.2525252525253, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17509539, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321118, Length=286, Percent_Identity=26.2237762237762, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320922, Length=270, Percent_Identity=25.9259259259259, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=25.4901960784314, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920384, Length=261, Percent_Identity=28.735632183908, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357079, Length=319, Percent_Identity=29.153605015674, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21355531, Length=245, Percent_Identity=22.4489795918367, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39866; Mature: 39735

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKINKIQNQLQNYEIDGLLITKKENRQYATGFTGSAGVVLITADAAVFITDFRYVDQA
CEEEHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCEEEEECCCEEEEEHHHHHHHH
NSQIKNAEIIMHKGNLEKEIANQVSKLNIQKLGIEENNMTLQQYKNLQKYVHTEMVQVCE
CCCCCCCEEEEECCCCHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
IIENIRLIKDTHEIETMKKAANIADEAFHHIITFLKPGISENDVRDELEFFMRKKGATSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
SFQIIVASGVRSSLPHGVASNKIIERGDIVTLDFGALYDGYCSDITRTVAIGEPSEEFKK
CEEEEEECCCHHHCCCCCCCCCEEECCCEEEEEHHHHHHHHHHHHHHEEECCCCHHHHHH
IYNVVREALKRGTEAIKPGETAKSIDDVTRNYITDCGYGQYFGHSTGHGLGLEIHEPLRL
HHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHC
SQESKATLEEGMVVTVEPGIYIPNWGGCRIEDDIVITKDGYEVITKSNRELIVIPC
CCHHHHHHHCCEEEEECCCEEECCCCCCEEECCEEEECCCHHEEECCCCEEEEEEC
>Mature Secondary Structure 
TLKINKIQNQLQNYEIDGLLITKKENRQYATGFTGSAGVVLITADAAVFITDFRYVDQA
EEEHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCEEEEECCCEEEEEHHHHHHHH
NSQIKNAEIIMHKGNLEKEIANQVSKLNIQKLGIEENNMTLQQYKNLQKYVHTEMVQVCE
CCCCCCCEEEEECCCCHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
IIENIRLIKDTHEIETMKKAANIADEAFHHIITFLKPGISENDVRDELEFFMRKKGATSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
SFQIIVASGVRSSLPHGVASNKIIERGDIVTLDFGALYDGYCSDITRTVAIGEPSEEFKK
CEEEEEECCCHHHCCCCCCCCCEEECCCEEEEEHHHHHHHHHHHHHHEEECCCCHHHHHH
IYNVVREALKRGTEAIKPGETAKSIDDVTRNYITDCGYGQYFGHSTGHGLGLEIHEPLRL
HHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHC
SQESKATLEEGMVVTVEPGIYIPNWGGCRIEDDIVITKDGYEVITKSNRELIVIPC
CCHHHHHHHCCEEEEECCCEEECCCCCCEEECCEEEECCCHHEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]