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The map label for this gene is rnc [H]

Identifier: 118479071

GI number: 118479071

Start: 3694670

End: 3695458

Strand: Reverse

Name: rnc [H]

Synonym: BALH_3480

Alternate gene names: 118479071

Gene position: 3695458-3694670 (Counterclockwise)

Preceding gene: 118479072

Following gene: 118479070

Centisome position: 70.29

GC content: 37.9

Gene sequence:

>789_bases
ATGAAGTCCCGTTTTTTAGCGGGGCTTCTCGGCTTATATCTGGAGGGACCTATGCCGTACCGTAAATATAGAGAAAAAAA
ATACGAAACAAAATATCGTGAAGCGTTTAAATTATTTCAAGAAAAGATAGGTATTACGTTTACAGATGAAAAATTATTGA
TTCAAGCATTTACGCATTCATCGTATGTGAATGAGCATCGAAAAAAACCACATGAAGACAATGAGCGTCTCGAATTTCTT
GGAGATGCAGTATTGGAACTTACTGTATCGCAGTATCTGTTTCAAAAATATCCGACAATGAGCGAAGGAGAGTTAACAAA
ACTACGTGCAGCAATTGTATGTGAACCATCTCTTGTTCGTTTTGCAAACGAGTTGTCATTTGGTAGCCTTGTTTTATTAG
GCAAAGGTGAGGAAATGACAGGTGGACGTGAACGACCAGCTTTATTAGCGGATGTCTTTGAAGCGTTTATTGGTGCCCTT
TATCTTGATCAAGGGCTAGAAACAGTATGGGGCTTTTTAAAAGAAATTGTATACCCTAAAATTAATGAAGGTGCTTTTTC
TCATGTGATGGATTATAAGAGTCAATTACAAGAGTTGATTCAGCGTGATGGTAGTGGCAATATTGAGTATCAAATTTTGC
AAGAAAAAGGCCCAGCCCACAATCGAGAATTTGTGTCACGTGTTACGTTAAATAACGTGGCTTTAGGACTTGGTAGTGGC
AAGTCGAAAAAAGAAGCAGAACAACAAGCTGCTGCAGAAGCGTTGAAAAAGTTAAAAGAACAACTATAA

Upstream 100 bases:

>100_bases
GAAGACGAATTCGAAATGGAAATTTCTGATGAAGATGCTGAAAAGATTGCTACTGTTGGCGATGCTGTGACTTACATAGA
GAGTCATCTATAATGCTTGA

Downstream 100 bases:

>100_bases
GGAATCCCCCTTTGAATGAGGGGGATTCCTTGTGCATAGAATGAAACTTTCTTTTCGTTTGTAAATGAAAGGAAAGGAAA
TCCGTATAAAAGTTGTTTTT

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKSRFLAGLLGLYLEGPMPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFL
GDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGAL
YLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSG
KSKKEAEQQAAAEALKKLKEQL

Sequences:

>Translated_262_residues
MKSRFLAGLLGLYLEGPMPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFL
GDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGAL
YLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSG
KSKKEAEQQAAAEALKKLKEQL
>Mature_262_residues
MKSRFLAGLLGLYLEGPMPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFL
GDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGAL
YLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSG
KSKKEAEQQAAAEALKKLKEQL

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=225, Percent_Identity=35.1111111111111, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI155030234, Length=225, Percent_Identity=35.1111111111111, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1788920, Length=223, Percent_Identity=35.4260089686099, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193202651, Length=244, Percent_Identity=32.7868852459016, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17506883, Length=244, Percent_Identity=32.7868852459016, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17552834, Length=266, Percent_Identity=27.8195488721804, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323895, Length=220, Percent_Identity=28.1818181818182, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137682, Length=229, Percent_Identity=31.0043668122271, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 29841; Mature: 29841

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRFLAGLLGLYLEGPMPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHS
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHH
SYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHH
FANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPK
HHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
INEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSG
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCC
KSKKEAEQQAAAEALKKLKEQL
CCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSRFLAGLLGLYLEGPMPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHS
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHH
SYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHH
FANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPK
HHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
INEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSG
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCC
KSKKEAEQQAAAEALKKLKEQL
CCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA