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The map label for this gene is infB [H]

Identifier: 118479033

GI number: 118479033

Start: 3651628

End: 3653748

Strand: Reverse

Name: infB [H]

Synonym: BALH_3441

Alternate gene names: 118479033

Gene position: 3653748-3651628 (Counterclockwise)

Preceding gene: 118479034

Following gene: 118479032

Centisome position: 69.5

GC content: 38.57

Gene sequence:

>2121_bases
ATGAAGGCTTTGCGAAAAAGCTGCGTAGCATGCTCGATACAAATTACCGGGGGTGAAGGTATGAGTAAAATTCGAGTGCA
TGAATATGCGAAAAAACATAATATCTCAAGTAAAGATCTTATGACAAAACTAAAAGAAATGAATATCGAGGTTTCGAATC
ATATGACAATGTTAGACGATGAAGTAGTAAACAAATTAGATAATGAGTATCAAGCTGAAAAACCTTCTGTTGCAGATGAG
TTTGAAGTAGAAGAAAAAGTTGTTCGTAGTAAAAAGAACAGCAATAAGAAAAAGAAAAAAGGCAAAGGAAACGAAGACAA
GCGTCAAGAGAACTTTGCTGGAAGACAACAAACACAAACTGTAGAAACACCAGATAAAATTACTTTCTCTGGAAGCCTTA
CAGTAGGTGACCTTGCTAAGAAATTAAGCAAAGAGCCATCTGAAATTATTAAAAAGCTCTTCATGCTTGGAATTATGGCA
ACAATTAACCAAGACTTAGATAAAGATACAATTGAGTTAATTGCTAACGACTACGGTATTGAAGTAGAAGAAGAAGTAAT
TGTTAGCGAGACTGAGTTTGAAACATTCATCGATGAGCAAGATGATGAAGAGAACTTAAAAGAGCGTCCAGCTGTAGTTA
CAATCATGGGACACGTTGACCATGGTAAAACAACATTACTTGACTCTATCCGTAACTCTAAAGTAACTGCTGGCGAAGCA
GGTGGAATTACTCAGCATATCGGTGCATACCAAGTTGAAGTAAATGACAAGAAGATTACATTCTTAGACACACCTGGTCA
CGCGGCGTTTACAACGATGCGTGCTCGTGGTGCACAAGTAACGGATATTACAATCCTTGTTGTTGCAGCTGATGACGGCG
TAATGCCACAAACAGTTGAAGCGATTAACCATGCGAAAGCAGCAGGAGTACCAATTATTGTTGCTGTGAATAAAATGGAT
AAACCAGCAGCAAATCCTGATCGCGTAATGCAAGAATTAACAGAATATGAATTAGTTCCAGAAGCATGGGGCGGAGACAC
AATTTTCGTACCAATTTCTGCAATTCAAGGCGAAGGAATTGACAACTTACTAGAAATGATTCTTCTTGTAAGTGAAGTAG
AAGAATATAAAGCAAATCCAAACCGCTATGCAACTGGTACTGTAATTGAAGCACAGCTTGATAAAGGTAAAGGAACTATC
GCGACATTACTTGTTCAAAACGGTACGCTTCGAGTTGGAGACCCAATCGTTGTTGGTACTTCATTCGGACGTGTTCGTGC
AATGGTAAGTGATATTGGTCGCCGTGTAAAAGTTGCTGGTCCATCAACTCCTGTTGAAATTACAGGTTTAAACGAAGTGC
CACAAGCGGGAGATCGTTTCATGGCATTCGCTGATGAGAAGAAAGCTCGTCAAATCGGTGAATCACGTGCGCAAGAAGCG
TTACTTGCTCAACGTGGTGAAAAATCTAAATTAAGCCTTGAAGATTTATTCCAACAAATCCAAGAGGGCGATGTAAAAGA
AATTAACTTAATTGTGAAAGCAGACGTACAAGGTTCTGTAGAAGCAATGGCAGCATCACTTCGTAAAATTGATGTTGAAG
GTGTTAAAGTTAAAATTATCCATACAGGCGTAGGTGCGATTACAGAATCTGATATCATTTTAGCTTCTGCATCTAATGCA
ATTGTAATTGGATTTAACGTACGCCCAGATGTGAATGCGAAGCGTACAGCTGAATTAGAGAACGTTGATATTCGTTTACA
CCGCATTATTTATAAAGTAATCGAAGAGATCGAAGCAGCGATGCAAGGTATGTTAGATCCAGAATTCGAAGAAAAAGTAA
TCGGTCAAGCAGAAGTACGTCAAACGTTTAAAGTAACAAAAGTTGGAACAATCGCAGGTTGTTACGTAACAGACGGTAAA
ATTACACGTGATAGTGGCGTGCGTATTATCCGTGATGGCGTAGTAATTTTCGAAGGACAACTTGATACGTTAAAACGATT
CAAAGACGACGTAAAAGAAGTTGCACAAAACTATGAGTGTGGTATTACAATTGAGAGATATAATGATCTTAAAGAAGGGG
ACATTATTGAAGCATACATTATGGAAGAAGTGAAGCGATGA

Upstream 100 bases:

>100_bases
AAAACGACGTACTACAACGTACCAATGAGAAAGGTCGAAAATCGACAACAATTAGGGCATGCGATTGGGAGAGATGAGCG
AGTCGTTGTAGCTGTGTTAG

Downstream 100 bases:

>100_bases
TTATCGCTTCACTCTCATTCGAGTGTATGATTTACGATGTGCATTCTTTAAAAGAGAAACGAGCAATTTTGCAACGGGTG
CTAACTCGAGTGAAGCAGCG

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MKALRKSCVACSIQITGGEGMSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADE
FEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMA
TINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEA
GGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMD
KPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTI
ATLLVQNGTLRVGDPIVVGTSFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEA
LLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNA
IVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGK
ITRDSGVRIIRDGVVIFEGQLDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR

Sequences:

>Translated_706_residues
MKALRKSCVACSIQITGGEGMSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADE
FEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMA
TINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEA
GGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMD
KPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTI
ATLLVQNGTLRVGDPIVVGTSFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEA
LLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNA
IVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGK
ITRDSGVRIIRDGVVIFEGQLDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR
>Mature_706_residues
MKALRKSCVACSIQITGGEGMSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADE
FEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMA
TINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEA
GGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMD
KPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTI
ATLLVQNGTLRVGDPIVVGTSFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEA
LLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNA
IVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGK
ITRDSGVRIIRDGVVIFEGQLDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR

Specific function: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 7

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family [H]

Homologues:

Organism=Homo sapiens, GI53729339, Length=651, Percent_Identity=36.2519201228879, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI53729337, Length=651, Percent_Identity=36.2519201228879, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI84043963, Length=463, Percent_Identity=26.3498920086393, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI157426893, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI34147630, Length=258, Percent_Identity=30.2325581395349, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI18390331, Length=142, Percent_Identity=31.6901408450704, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1789559, Length=579, Percent_Identity=54.7495682210708, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI2367247, Length=225, Percent_Identity=32, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI48994988, Length=137, Percent_Identity=36.4963503649635, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788922, Length=233, Percent_Identity=29.6137339055794, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790412, Length=234, Percent_Identity=32.9059829059829, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789737, Length=234, Percent_Identity=32.9059829059829, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994658, Length=539, Percent_Identity=37.291280148423, Blast_Score=328, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI212656558, Length=568, Percent_Identity=26.2323943661972, Blast_Score=129, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17557151, Length=219, Percent_Identity=30.5936073059361, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556456, Length=266, Percent_Identity=30.8270676691729, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25141371, Length=254, Percent_Identity=28.3464566929134, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324550, Length=614, Percent_Identity=36.9706840390879, Blast_Score=361, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319282, Length=531, Percent_Identity=27.1186440677966, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6324761, Length=258, Percent_Identity=31.0077519379845, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28572034, Length=653, Percent_Identity=36.7534456355283, Blast_Score=368, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24656849, Length=456, Percent_Identity=27.4122807017544, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI160714833, Length=122, Percent_Identity=54.0983606557377, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78706572, Length=224, Percent_Identity=28.125, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363316, Length=263, Percent_Identity=30.7984790874525, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17864358, Length=263, Percent_Identity=30.7984790874525, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17137380, Length=272, Percent_Identity=28.3088235294118, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19921738, Length=248, Percent_Identity=31.0483870967742, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922690, Length=230, Percent_Identity=27.8260869565217, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006847
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000178
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2; PF04760 IF2_N [H]

EC number: NA

Molecular weight: Translated: 77760; Mature: 77760

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALRKSCVACSIQITGGEGMSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDD
CCHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCEEHHCCEEHHHH
EVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQT
HHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCCCC
VETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGI
CCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
EVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEA
CCCHHEEEECHHHHHHCCCCCCHHHHHHCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCC
GGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVE
CCCHHHCCEEEEEECCCEEEEEECCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHH
AINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGI
HHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHCCCCH
DNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGT
HHHHHHHHHHHHHHHHCCCCCCEECCEEEEEEECCCCCEEEEEEEECCEEEECCEEEEEC
SFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEA
CHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKII
HHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHEECCCEEEEEE
HTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAA
EECCCCEECCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQ
HHCCCCCCHHHHHCCHHHHHHHHEEEEECEEEEEEEECCEEECCCCCEEEECCEEEEECC
LDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKALRKSCVACSIQITGGEGMSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDD
CCHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCEEHHCCEEHHHH
EVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQT
HHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCCCC
VETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGI
CCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
EVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEA
CCCHHEEEECHHHHHHCCCCCCHHHHHHCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCC
GGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVE
CCCHHHCCEEEEEECCCEEEEEECCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHH
AINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGI
HHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHCCCCH
DNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGT
HHHHHHHHHHHHHHHHCCCCCCEECCEEEEEEECCCCCEEEEEEEECCEEEECCEEEEEC
SFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEA
CHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKII
HHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHEECCCEEEEEE
HTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAA
EECCCCEECCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQ
HHCCCCCCHHHHHCCHHHHHHHHEEEEECEEEEEEEECCEEECCCCCEEEECCEEEEECC
LDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA