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The map label for this gene is ymxG [H]

Identifier: 118479025

GI number: 118479025

Start: 3643905

End: 3645203

Strand: Reverse

Name: ymxG [H]

Synonym: BALH_3433

Alternate gene names: 118479025

Gene position: 3645203-3643905 (Counterclockwise)

Preceding gene: 118479026

Following gene: 118479024

Centisome position: 69.34

GC content: 33.49

Gene sequence:

>1299_bases
TTGTTATCATTAAATAATAGCATTTATTTAGAGAAACTGGCAGTAGGAGGAAAGTTTTTGATTAAAAAATATACTTGTAA
AAATGGTGTAAGAATAGTTATGGAGAATATACCAACTGTAAGATCGGTTGCGATTGGTATTTGGATCCATGCAGGATCAA
GAAATGAAAATGAAAAAAACAACGGGATTTCTCACTTTTTAGAGCATATGTTCTTTAAGGGGACGGAAACTCGTAGTGCA
CGCGAAATTGCAGAATCATTTGATAGCATTGGTGGACAAGTGAATGCTTTTACTTCAAAAGAATACACTTGTTACTATGC
AAAAGTGCTAGATGAGCATGCTAAATATGCTTTAGATGTATTAGCAGATATGTTCTTTAATTCAACATTTGATGAAGAAG
AACTGAAAAAAGAGAAGAATGTCGTATGTGAAGAAATTAAAATGTACGAAGACGCTCCAGATGATATTGTGCATGATATG
TTAACGAAAGCAACATATGAAACGCATCCGCTTGGATATCCTATTTTAGGAACAGAAGAAACGCTTAATACGTTTACAGG
TGATACGCTACGCCAATATATTAAAGATCATTACACACCTGAAAATGTAGTTGTATCAATTGCAGGAAATATTGATGAAG
CCTTTTTACAAACGGTAGAGCAATATTTCGGTAGTTATGAAGGAACGACAAACCGTGAACAAGTACATAGCCCAATTTTC
CACTTTAATAAGGTAGCACGTAAAAAGGAAACAGAACAAGCTCATTTATGTTTAGGATATAAAGGCTTACAAATGGGACA
CGAAGATATTTATAACTTAATTGTATTAAATAACGTTTTAGGCGGTAGTATGAGTAGCCGTTTATTCCAAGAAGTACGTG
AGCAACGCGGGTTAGCTTACTCAGTGTTTTCTTACCATTCTTCTTATGAAGATACAGGTATGTTAACGCTGTATGGTGGA
ACAGGTAGCCAACAATTAGATACACTGTATGAAACAATGCAAGAAACATTAGAAACATTGAAAAATACAGGTATTACAGA
AAAAGAGCTTATGAATAGTAAAGAGCAATTAAAAGGAAACTTAATGTTAAGTTTAGAAAGTACGAATAGCCGTATGAGCC
GTAATGGTAAAAATGAATTGCTACTTCGTAAGCATCGTTCACTTGATGAGATTATTGAAAGTGTAAACACTGTAACAAAA
GAAAATGTAGATGAATTAATTCGTAACATGTTTACAGATGAATTCTCTGCAGCATTAATTAGTCCAGATGGAAAACTTCC
AAAAGGAATAAAACTATAA

Upstream 100 bases:

>100_bases
CAAAATTGAAGGAACAAGGATATAAAGTAGGGAATATAACAGAATTACTGGATGAAAAACGTGTGGATTAAATACATTTG
CATGACATTCATCCTTAAAC

Downstream 100 bases:

>100_bases
TTGCTATATATGATTTAAAAATAACCGTATCTCTTTTAAACGAGATACGGTTATTTTTTGTGGATATATAGAATAGGTAC
TAATTATGGATAACTTAAAT

Product: zinc protease

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLSLNNSIYLEKLAVGGKFLIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENEKNNGISHFLEHMFFKGTETRSA
REIAESFDSIGGQVNAFTSKEYTCYYAKVLDEHAKYALDVLADMFFNSTFDEEELKKEKNVVCEEIKMYEDAPDDIVHDM
LTKATYETHPLGYPILGTEETLNTFTGDTLRQYIKDHYTPENVVVSIAGNIDEAFLQTVEQYFGSYEGTTNREQVHSPIF
HFNKVARKKETEQAHLCLGYKGLQMGHEDIYNLIVLNNVLGGSMSSRLFQEVREQRGLAYSVFSYHSSYEDTGMLTLYGG
TGSQQLDTLYETMQETLETLKNTGITEKELMNSKEQLKGNLMLSLESTNSRMSRNGKNELLLRKHRSLDEIIESVNTVTK
ENVDELIRNMFTDEFSAALISPDGKLPKGIKL

Sequences:

>Translated_432_residues
MLSLNNSIYLEKLAVGGKFLIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENEKNNGISHFLEHMFFKGTETRSA
REIAESFDSIGGQVNAFTSKEYTCYYAKVLDEHAKYALDVLADMFFNSTFDEEELKKEKNVVCEEIKMYEDAPDDIVHDM
LTKATYETHPLGYPILGTEETLNTFTGDTLRQYIKDHYTPENVVVSIAGNIDEAFLQTVEQYFGSYEGTTNREQVHSPIF
HFNKVARKKETEQAHLCLGYKGLQMGHEDIYNLIVLNNVLGGSMSSRLFQEVREQRGLAYSVFSYHSSYEDTGMLTLYGG
TGSQQLDTLYETMQETLETLKNTGITEKELMNSKEQLKGNLMLSLESTNSRMSRNGKNELLLRKHRSLDEIIESVNTVTK
ENVDELIRNMFTDEFSAALISPDGKLPKGIKL
>Mature_432_residues
MLSLNNSIYLEKLAVGGKFLIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENEKNNGISHFLEHMFFKGTETRSA
REIAESFDSIGGQVNAFTSKEYTCYYAKVLDEHAKYALDVLADMFFNSTFDEEELKKEKNVVCEEIKMYEDAPDDIVHDM
LTKATYETHPLGYPILGTEETLNTFTGDTLRQYIKDHYTPENVVVSIAGNIDEAFLQTVEQYFGSYEGTTNREQVHSPIF
HFNKVARKKETEQAHLCLGYKGLQMGHEDIYNLIVLNNVLGGSMSSRLFQEVREQRGLAYSVFSYHSSYEDTGMLTLYGG
TGSQQLDTLYETMQETLETLKNTGITEKELMNSKEQLKGNLMLSLESTNSRMSRNGKNELLLRKHRSLDEIIESVNTVTK
ENVDELIRNMFTDEFSAALISPDGKLPKGIKL

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=420, Percent_Identity=30, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI46593007, Length=415, Percent_Identity=25.3012048192771, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI24308013, Length=463, Percent_Identity=25.2699784017279, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI50592988, Length=425, Percent_Identity=20.7058823529412, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI155969707, Length=119, Percent_Identity=36.1344537815126, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787770, Length=177, Percent_Identity=28.8135593220339, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI2367164, Length=172, Percent_Identity=26.1627906976744, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=416, Percent_Identity=28.6057692307692, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17553678, Length=418, Percent_Identity=26.3157894736842, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17510601, Length=368, Percent_Identity=22.2826086956522, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323192, Length=395, Percent_Identity=31.6455696202532, Blast_Score=200, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6321813, Length=420, Percent_Identity=26.9047619047619, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6319426, Length=400, Percent_Identity=22.25, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357875, Length=412, Percent_Identity=29.6116504854369, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24646943, Length=412, Percent_Identity=29.6116504854369, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI19921772, Length=455, Percent_Identity=24.8351648351648, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24665395, Length=406, Percent_Identity=21.4285714285714, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49084; Mature: 49084

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLNNSIYLEKLAVGGKFLIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENEKN
CCCCCCCHHHHHHHCCCHHHHHHHHHCCCCEEHHHCCCHHHHEEEEEEEEECCCCCCCCC
NGISHFLEHMFFKGTETRSAREIAESFDSIGGQVNAFTSKEYTCYYAKVLDEHAKYALDV
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
LADMFFNSTFDEEELKKEKNVVCEEIKMYEDAPDDIVHDMLTKATYETHPLGYPILGTEE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHH
TLNTFTGDTLRQYIKDHYTPENVVVSIAGNIDEAFLQTVEQYFGSYEGTTNREQVHSPIF
HHHHCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
HFNKVARKKETEQAHLCLGYKGLQMGHEDIYNLIVLNNVLGGSMSSRLFQEVREQRGLAY
HHHHHHHHHCCCHHHHEECCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEE
SVFSYHSSYEDTGMLTLYGGTGSQQLDTLYETMQETLETLKNTGITEKELMNSKEQLKGN
EHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCC
LMLSLESTNSRMSRNGKNELLLRKHRSLDEIIESVNTVTKENVDELIRNMFTDEFSAALI
EEEEEECCCHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
SPDGKLPKGIKL
CCCCCCCCCCCC
>Mature Secondary Structure
MLSLNNSIYLEKLAVGGKFLIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENEKN
CCCCCCCHHHHHHHCCCHHHHHHHHHCCCCEEHHHCCCHHHHEEEEEEEEECCCCCCCCC
NGISHFLEHMFFKGTETRSAREIAESFDSIGGQVNAFTSKEYTCYYAKVLDEHAKYALDV
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
LADMFFNSTFDEEELKKEKNVVCEEIKMYEDAPDDIVHDMLTKATYETHPLGYPILGTEE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHH
TLNTFTGDTLRQYIKDHYTPENVVVSIAGNIDEAFLQTVEQYFGSYEGTTNREQVHSPIF
HHHHCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
HFNKVARKKETEQAHLCLGYKGLQMGHEDIYNLIVLNNVLGGSMSSRLFQEVREQRGLAY
HHHHHHHHHCCCHHHHEECCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEE
SVFSYHSSYEDTGMLTLYGGTGSQQLDTLYETMQETLETLKNTGITEKELMNSKEQLKGN
EHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCC
LMLSLESTNSRMSRNGKNELLLRKHRSLDEIIESVNTVTKENVDELIRNMFTDEFSAALI
EEEEEECCCHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
SPDGKLPKGIKL
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]