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The map label for this gene is ccdA [H]

Identifier: 118478899

GI number: 118478899

Start: 3502060

End: 3502824

Strand: Reverse

Name: ccdA [H]

Synonym: BALH_3300

Alternate gene names: 118478899

Gene position: 3502824-3502060 (Counterclockwise)

Preceding gene: 118478902

Following gene: 118478898

Centisome position: 66.63

GC content: 33.86

Gene sequence:

>765_bases
TTGTTCATAGTATTTTTACGTGTTTTTGCTACAATATGTAAGGAGAGGAGTGGAACAATGCAAGATATTAGTATTTTTTT
AGCGTTTGGCGCCGGGTTTTTATCATTTATTTCCCCATGTTGCTTGCCGCTTTATCCGGCATTTCTATCATATATAACAG
GTATGTCGGTTTCTGAGCTGAAAGAAGAAAATGCAATGCTTCGCAAAAGAAGTATGATACATACAGCGTTTTTCTTACTT
GGATTTTCAATTATATTTATTGCAATTGGATTTGGTACAAGTTTTATTGGAGGCATCTTTACAAATTATAAAGATTTAAT
TAGACAGTTAGGTGGTATATTTATCATTGTGTTCGGTCTTATTATTGTCGGTGTGTTTAAGCCGAAGTTTTTAATGCAAG
ATCGTAAATTTACGTTTAAAAATCGTCCGAGTGGTTATTTTGGATCTGTTTTAATTGGGTTGGCATTTGCTGCAGGGTGG
ACGCCTTGTACAGGACCTATTTTAGTGTCTGTAATCGGATTAGCAGCAACAAATCCAGAATCAGCAATGATTTATATGAT
TGCATATATACTTGGATTCGCTATTCCGTTCTTCGTGCTATCATTCTTTATTACGAAAATGTCTTGGATTAAAAGAAATA
GTATGAAGTTCATGAAAATCGGGGGATACGTTATGATTGTCATGGGTATCTTCCTATATTTTAACTGGATGACGAAAATT
ATAGTATATTTCTCAAGTTTATTTGGTGGATTTACTGGTTTTTAG

Upstream 100 bases:

>100_bases
GATTTTTCTATATATATAGAAGGAACTGAAAACGTTTTTTTTGAAAAAGCGTGAAAGGGTAGTTTTTCTTATTATCACGT
TGGAAAAGTGATTTCACGAA

Downstream 100 bases:

>100_bases
TATTATTCTGTGAAAATGTTGGAAATACTAACGGAAAAGCATATAATGAAAGTATATTTTGCATATAGCCACAAAAAAGG
ATGAGAAAATATGAACATAG

Product: cytochrome c-type biogenesis protein (holocytochrome-c synthase)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFIVFLRVFATICKERSGTMQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLL
GFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGW
TPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIVMGIFLYFNWMTKI
IVYFSSLFGGFTGF

Sequences:

>Translated_254_residues
MFIVFLRVFATICKERSGTMQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLL
GFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGW
TPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIVMGIFLYFNWMTKI
IVYFSSLFGGFTGF
>Mature_254_residues
MFIVFLRVFATICKERSGTMQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLL
GFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGW
TPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIVMGIFLYFNWMTKI
IVYFSSLFGGFTGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 28464; Mature: 28464

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]