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The map label for this gene is catB2 [H]

Identifier: 118478793

GI number: 118478793

Start: 3369909

End: 3370466

Strand: Direct

Name: catB2 [H]

Synonym: BALH_3185

Alternate gene names: 118478793

Gene position: 3369909-3370466 (Clockwise)

Preceding gene: 118478786

Following gene: 118478795

Centisome position: 64.1

GC content: 36.02

Gene sequence:

>558_bases
ATGTTATATTTAAATCAAAAACCAGAATATAGTAAGTATGATATCGGTGATTATACTTATAGTAAAGTCGGACCAACTAT
TTTTTCTTGGAACGATGAAACGAAATTAAAAATAGGTAAGTTTTGTTCATTAGGAGAAGAAGTTGTTTTCCTACTTGGTG
GTGAACATCGTGCCGATTGGATAACAACTTATCCATTTAATGCTCTCTTCGGTGAAGGAGCACATATTACTGGTCACCCT
TCTTCTAAAGGTGATATCGTAGTCGGCAATGATGTATGGATTGGTTATCAATCCTGCATTTTATCTGGTGTTACAATTGG
TAATGGGGCCATTATTGGCGCAAAGAGTGTCGTTACAAAAGATGTACCTCCATATGCAATTGTGGCTGGTAATCCAGCAA
AATTTATTCGATATCGTTTCCCGCAAGAAACAATTGACAAACTAGAGCATCTTGCATGGTGGGATTGGGACATTTCTGTT
ATAAAAGGAGCTATTCCATTACTACTCTCCGACAAAATCAATGAATTTTTCACATCGTCTGAAAATGAATCTAAATGA

Upstream 100 bases:

>100_bases
CCTTTTTGTTCAATTCACCTACTAACACAGCTCACCTTGCTACATCTTGCATATAATATTCCATACGCATCGCTTAATTG
AGAAAGGAGGCTGAAGAAGC

Downstream 100 bases:

>100_bases
TTCATACGAAAAGAGCATCTTATTCTTTCAAGATGCTCTTTTTATTTTTATTTTTTATGCCCGTGCAACTGATTACACGG
AGAACATTGAAATAGAATTT

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLYLNQKPEYSKYDIGDYTYSKVGPTIFSWNDETKLKIGKFCSLGEEVVFLLGGEHRADWITTYPFNALFGEGAHITGHP
SSKGDIVVGNDVWIGYQSCILSGVTIGNGAIIGAKSVVTKDVPPYAIVAGNPAKFIRYRFPQETIDKLEHLAWWDWDISV
IKGAIPLLLSDKINEFFTSSENESK

Sequences:

>Translated_185_residues
MLYLNQKPEYSKYDIGDYTYSKVGPTIFSWNDETKLKIGKFCSLGEEVVFLLGGEHRADWITTYPFNALFGEGAHITGHP
SSKGDIVVGNDVWIGYQSCILSGVTIGNGAIIGAKSVVTKDVPPYAIVAGNPAKFIRYRFPQETIDKLEHLAWWDWDISV
IKGAIPLLLSDKINEFFTSSENESK
>Mature_185_residues
MLYLNQKPEYSKYDIGDYTYSKVGPTIFSWNDETKLKIGKFCSLGEEVVFLLGGEHRADWITTYPFNALFGEGAHITGHP
SSKGDIVVGNDVWIGYQSCILSGVTIGNGAIIGAKSVVTKDVPPYAIVAGNPAKFIRYRFPQETIDKLEHLAWWDWDISV
IKGAIPLLLSDKINEFFTSSENESK

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=93, Percent_Identity=39.7849462365591, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786664, Length=106, Percent_Identity=33.0188679245283, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 20601; Mature: 20601

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLNQKPEYSKYDIGDYTYSKVGPTIFSWNDETKLKIGKFCSLGEEVVFLLGGEHRADW
CEECCCCCCCCCCCCCCEEHHHCCCEEEECCCCCEEEEHHHHCCCCEEEEEECCCCCCCE
ITTYPFNALFGEGAHITGHPSSKGDIVVGNDVWIGYQSCILSGVTIGNGAIIGAKSVVTK
EEECCCHHHHCCCCEEECCCCCCCCEEECCCEEECHHHHHHCCEEECCCEEEECCHHEEC
DVPPYAIVAGNPAKFIRYRFPQETIDKLEHLAWWDWDISVIKGAIPLLLSDKINEFFTSS
CCCCEEEEECCHHHEEEEECCHHHHHHHHHHEECCCCHHHHHCHHHHHHHHHHHHHHCCC
ENESK
CCCCC
>Mature Secondary Structure
MLYLNQKPEYSKYDIGDYTYSKVGPTIFSWNDETKLKIGKFCSLGEEVVFLLGGEHRADW
CEECCCCCCCCCCCCCCEEHHHCCCEEEECCCCCEEEEHHHHCCCCEEEEEECCCCCCCE
ITTYPFNALFGEGAHITGHPSSKGDIVVGNDVWIGYQSCILSGVTIGNGAIIGAKSVVTK
EEECCCHHHHCCCCEEECCCCCCCCEEECCCEEECHHHHHHCCEEECCCEEEECCHHEEC
DVPPYAIVAGNPAKFIRYRFPQETIDKLEHLAWWDWDISVIKGAIPLLLSDKINEFFTSS
CCCCEEEEECCHHHEEEEECCHHHHHHHHHHEECCCCHHHHHCHHHHHHHHHHHHHHCCC
ENESK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]