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The map label for this gene is qor [C]

Identifier: 118478766

GI number: 118478766

Start: 3338063

End: 3339061

Strand: Direct

Name: qor [C]

Synonym: BALH_3158

Alternate gene names: 118478766

Gene position: 3338063-3339061 (Clockwise)

Preceding gene: 118478765

Following gene: 118478767

Centisome position: 63.5

GC content: 34.13

Gene sequence:

>999_bases
ATGAAAGCAATGATAATTGATAAGTACGGGAAAGTTCCAATGCGTATGGCAGAGGTACCTACTCCTGAAATAAATGAATA
TGAAGTACTCGCTGAAATTCATGCAGCTAGTATTAACCCAATTGACTTTAAAATACGTGATGGAAAAGTAAAGATGTTAC
TTAAATATGAAATGCCCTTAATTCTTGGTAATGACTTTTCCGGTGTCATCGTAAAGGTTGGATCAAAAGTGACTCGTTTT
AAAGTCGGCGATGAAATATATGCACGTCCAAGAAAAAATAAGATTGGTACTTTCGCGGAGTATATAGCCATTCATGAAGA
TGATATAGCTTTAAAACCGAAAAATTTAAGTTTTGAAGAAGCTGCTTCAATTCCACTTGTTGGCTTAACATCATATCAAG
CATTACATGACATTATGCAATTACAAAAAGATCAAAAGATTTTAATTCACGCTGGATCTGGTGGTGTTGGTACTTTCGCA
ATTCAGTTAGCAAAAATAATGGGCGCTACCGTTACAACGACTGCTAGTGAAGCTGGTTCCAATTTAGTAAAGTCTCTTGG
CGCAGATCAAATTATTAATTACAAAACAGAAAAATTTGAAGAAATACTAAAAGATTATGATGCAGTATTTGATACCATTG
GTGGTACAACACTTGAAAAATCATTCAATATTATAAAAAGCGGCGGTAACATTGTTTCCGTTTCAGGAATGCCGAATGCT
CGATTCGGTAAAGAATTCGGTTCAGGATTTTTCAAAACACTCTTATTTTCATTAGCAAGTAAAAAACTTACTGCACTTGA
AAAGAAGCATAATGCTCAATATTCATTTTTATTTATGAAGCCAAGCGGGGATCAATTACGTATTATCGCAAATTATATTG
AAGCCGGAAAAATCAAACCGGTAATCGATCGAGTTTTTTCATTTGAAGATGCTCAAAAAGCAATGGAATATTCAGAGGCT
GGCAGAGCAAAAGGAAAAATAATCGTAAAAATTAAGTAA

Upstream 100 bases:

>100_bases
TGCCCATAAAAGTCCGATTGGTTCAACTAATAATCAGTGGGGGATGAAGAACCCCCCACTGATTAAAGTTTCACTTTATT
GAAATTTGGAGGTATAAGAA

Downstream 100 bases:

>100_bases
TAATAAAGACTCCATTTTCTTAAGATGGGGTTTTTATATTTGCTGTTAAATAGACATAGTGCAGTGAAGTCCTTACAATA
GATTGCAAGGGGAAATATCA

Product: alcohol dehydrogenase, zinc-containing

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKAMIIDKYGKVPMRMAEVPTPEINEYEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPLILGNDFSGVIVKVGSKVTRF
KVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGSNLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFNIIKSGGNIVSVSGMPNA
RFGKEFGSGFFKTLLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKPVIDRVFSFEDAQKAMEYSEA
GRAKGKIIVKIK

Sequences:

>Translated_332_residues
MKAMIIDKYGKVPMRMAEVPTPEINEYEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPLILGNDFSGVIVKVGSKVTRF
KVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGSNLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFNIIKSGGNIVSVSGMPNA
RFGKEFGSGFFKTLLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKPVIDRVFSFEDAQKAMEYSEA
GRAKGKIIVKIK
>Mature_332_residues
MKAMIIDKYGKVPMRMAEVPTPEINEYEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPLILGNDFSGVIVKVGSKVTRF
KVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGSNLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFNIIKSGGNIVSVSGMPNA
RFGKEFGSGFFKTLLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKPVIDRVFSFEDAQKAMEYSEA
GRAKGKIIVKIK

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=358, Percent_Identity=35.7541899441341, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI22538446, Length=346, Percent_Identity=30.3468208092486, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI22538444, Length=346, Percent_Identity=30.3468208092486, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=29.4871794871795, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=27.0769230769231, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=27.0769230769231, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI194239676, Length=178, Percent_Identity=32.0224719101124, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=25.7879656160458, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI28557745, Length=338, Percent_Identity=26.3313609467456, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI67078404, Length=334, Percent_Identity=24.8502994011976, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI67078406, Length=297, Percent_Identity=25.9259259259259, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI90669511, Length=116, Percent_Identity=34.4827586206897, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI41872631, Length=233, Percent_Identity=24.8927038626609, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=232, Percent_Identity=35.3448275862069, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790045, Length=350, Percent_Identity=21.1428571428571, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789651, Length=246, Percent_Identity=26.0162601626016, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=366, Percent_Identity=29.7814207650273, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17507255, Length=344, Percent_Identity=25.8720930232558, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988145, Length=273, Percent_Identity=26.7399267399267, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536829, Length=236, Percent_Identity=28.3898305084746, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562876, Length=268, Percent_Identity=29.1044776119403, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17556000, Length=347, Percent_Identity=23.342939481268, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323801, Length=339, Percent_Identity=27.1386430678466, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319520, Length=245, Percent_Identity=31.4285714285714, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320948, Length=382, Percent_Identity=25.130890052356, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324195, Length=243, Percent_Identity=32.5102880658436, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319401, Length=157, Percent_Identity=31.8471337579618, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581341, Length=364, Percent_Identity=27.4725274725275, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24581339, Length=364, Percent_Identity=27.4725274725275, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI45550423, Length=253, Percent_Identity=24.1106719367589, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920632, Length=233, Percent_Identity=27.4678111587983, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330659, Length=233, Percent_Identity=27.4678111587983, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR014182
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36590; Mature: 36590

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMIIDKYGKVPMRMAEVPTPEINEYEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPL
CCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCE
ILGNDFSGVIVKVGSKVTRFKVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEE
EECCCCCCEEEEECCCEEEEECCCHHHCCCCCCCCHHHHHHHEEECCCCEECCCCCCHHH
AASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFAIQLAKIMGATVTTTASEAGS
HCCCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECHHHHHH
NLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFNIIKSGGNIVSVSGMPNA
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCEEEECCCCCC
RFGKEFGSGFFKTLLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEHHHCCCCCH
VIDRVFSFEDAQKAMEYSEAGRAKGKIIVKIK
HHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MKAMIIDKYGKVPMRMAEVPTPEINEYEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPL
CCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCE
ILGNDFSGVIVKVGSKVTRFKVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEE
EECCCCCCEEEEECCCEEEEECCCHHHCCCCCCCCHHHHHHHEEECCCCEECCCCCCHHH
AASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFAIQLAKIMGATVTTTASEAGS
HCCCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECHHHHHH
NLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFNIIKSGGNIVSVSGMPNA
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCEEEECCCCCC
RFGKEFGSGFFKTLLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEHHHCCCCCH
VIDRVFSFEDAQKAMEYSEAGRAKGKIIVKIK
HHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA