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The map label for this gene is uvrX [H]

Identifier: 118478553

GI number: 118478553

Start: 3110461

End: 3111753

Strand: Direct

Name: uvrX [H]

Synonym: BALH_2929

Alternate gene names: 118478553

Gene position: 3110461-3111753 (Clockwise)

Preceding gene: 118478551

Following gene: 118478554

Centisome position: 59.17

GC content: 34.18

Gene sequence:

>1293_bases
ATGTTCTCATTATTAGGAGGAGTTATAGTGTATGACTATTCAATTTTACCGGATAGAATCATTTTATGTGTTGATCTTCG
TAGCTTTTATGCTTCTGTTAGTTGCATCAAAATGGGAGTAGACCCACTTCATACAAAATTAGCTGTAGTTGGTGATGTGA
ATCGAAATGGGTCCATTGTTTTAGCCGCAACTCCACCTTTAAAAGCGATGGGAGTAAAGAAGTTGGCAAGGCTATACGAG
ATTCCTCGACAAAAAGATATTCTTATTGTGAATCCAATTATGGGAACCTATATTAAGTGCTCCAATTACATAACGAAGTT
AGCTCTACAATATGTTCCTATTGAAGACTTTCATCAATACAGCATCGATGAATTTTTTATGGATATTACCGATAGCATCC
ATCTATTTGCCCGGAATCCAAATGAATTTGCATTACAGTTTAAACGTGAAATATATGAACATACACGAATTGAATGCACA
ATCGGGATTGCACCTAACCTATTGATGAGTAAGGTGGCCTTAGATATTGAAGCAAAGAAAAAGAAAGACGGAATCGCTTA
TTGGAAATACGAAGATATACCTACAAAATTATGGAGCATACGACCGCTTAGTAAGTTTTGGGGGATTTCGCATAAAACAG
AAACAAAATTAAATCAAAAAGGGATACATTCAATTGGAGATTTAGCTCATTATCCTCTTAAATATTTAAAACAAAGCTTC
GGCGTGATTGGCGAAGAATTACACTTACATAGTAATGGGATTGATTTTAGTCGAATTTCAGAGAAATATGTTCCGGTTAC
AACTTCTATAGGAAAAAGCCAAATTTTAATGCGTGATTATACAATAGAAGAATTTCCGATTATCCTACTGGAACATACCG
AAGAAGTTTGCTATCGATTAAGACAACAAAACAAACTTGCTCAAACTGTTCAATTTTCAATTGGATATAGTAAAAGTTAT
TCGGGTGGCTTTAGCAAAACACATACCTTAAGCCGTCCCACCAACTTAACCATGGACATTTATCAAGTTTGTCTATATTT
TCTACATCAACAATATACTGGAGAACCAATTAGAAGTATTACTATTTCTCTAACAAAACTAATTGGTGAAGGAGAAGAAC
AAATTTCCCTTTTTGATAACATCATACAACGAGAAAAAGAAATAAAGCTAACGAAAGTAATGGATGAAATACGCACAAAG
TTTGGAAAAAATAGCATATTAAGAGGAATTTCCTATACAAATAATGCAACAGCAAGATACAGAAACACACTGTTAGGGGG
ACACAAAGCATGA

Upstream 100 bases:

>100_bases
GTTTAACATATTTCTACTACATATAATTAAATATTTTTTTCAAAAACCACTTCATGAAAGAACATAAGTTCGTGTATAAT
AAGAACAGAAATAAGAACAA

Downstream 100 bases:

>100_bases
ACAACGCTAATATGCCAAAAGGCAGAGGAATGGTAAAATGGACGCCGTTTGCAGCAATGCCAGAACAATTCGTCGGAATA
CGCGAAATGATCAAAGAGAA

Product: DNA-damage repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MFSLLGGVIVYDYSILPDRIILCVDLRSFYASVSCIKMGVDPLHTKLAVVGDVNRNGSIVLAATPPLKAMGVKKLARLYE
IPRQKDILIVNPIMGTYIKCSNYITKLALQYVPIEDFHQYSIDEFFMDITDSIHLFARNPNEFALQFKREIYEHTRIECT
IGIAPNLLMSKVALDIEAKKKKDGIAYWKYEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLAHYPLKYLKQSF
GVIGEELHLHSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRLRQQNKLAQTVQFSIGYSKSY
SGGFSKTHTLSRPTNLTMDIYQVCLYFLHQQYTGEPIRSITISLTKLIGEGEEQISLFDNIIQREKEIKLTKVMDEIRTK
FGKNSILRGISYTNNATARYRNTLLGGHKA

Sequences:

>Translated_430_residues
MFSLLGGVIVYDYSILPDRIILCVDLRSFYASVSCIKMGVDPLHTKLAVVGDVNRNGSIVLAATPPLKAMGVKKLARLYE
IPRQKDILIVNPIMGTYIKCSNYITKLALQYVPIEDFHQYSIDEFFMDITDSIHLFARNPNEFALQFKREIYEHTRIECT
IGIAPNLLMSKVALDIEAKKKKDGIAYWKYEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLAHYPLKYLKQSF
GVIGEELHLHSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRLRQQNKLAQTVQFSIGYSKSY
SGGFSKTHTLSRPTNLTMDIYQVCLYFLHQQYTGEPIRSITISLTKLIGEGEEQISLFDNIIQREKEIKLTKVMDEIRTK
FGKNSILRGISYTNNATARYRNTLLGGHKA
>Mature_430_residues
MFSLLGGVIVYDYSILPDRIILCVDLRSFYASVSCIKMGVDPLHTKLAVVGDVNRNGSIVLAATPPLKAMGVKKLARLYE
IPRQKDILIVNPIMGTYIKCSNYITKLALQYVPIEDFHQYSIDEFFMDITDSIHLFARNPNEFALQFKREIYEHTRIECT
IGIAPNLLMSKVALDIEAKKKKDGIAYWKYEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLAHYPLKYLKQSF
GVIGEELHLHSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRLRQQNKLAQTVQFSIGYSKSY
SGGFSKTHTLSRPTNLTMDIYQVCLYFLHQQYTGEPIRSITISLTKLIGEGEEQISLFDNIIQREKEIKLTKVMDEIRTK
FGKNSILRGISYTNNATARYRNTLLGGHKA

Specific function: Involved In Uv Protection And Mutation. Essential For Induced (Or Sos) Mutagenesis. May Modify The DNA Replication Machinery To Allow Bypass Synthesis Across A Damaged Template. [C]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=401, Percent_Identity=23.4413965087282, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786425, Length=272, Percent_Identity=25.3676470588235, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 49213; Mature: 49213

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSLLGGVIVYDYSILPDRIILCVDLRSFYASVSCIKMGVDPLHTKLAVVGDVNRNGSIV
CCHHHCCHHEEECEECCCCEEEEEEHHHHHHHHHHHHHCCCHHHCEEEEEEECCCCCCEE
LAATPPLKAMGVKKLARLYEIPRQKDILIVNPIMGTYIKCSNYITKLALQYVPIEDFHQY
EEECCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SIDEFFMDITDSIHLFARNPNEFALQFKREIYEHTRIECTIGIAPNLLMSKVALDIEAKK
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCC
KKDGIAYWKYEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLAHYPLKYLKQSF
CCCCEEEEEECCCCCHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIGEELHLHSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRL
CCCCCEEEEECCCCCHHHHCCCCCCEEECCCCCEEEEECCCCCCCCEEEEECCHHHHHHH
RQQNKLAQTVQFSIGYSKSYSGGFSKTHTLSRPTNLTMDIYQVCLYFLHQQYTGEPIRSI
HHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
TISLTKLIGEGEEQISLFDNIIQREKEIKLTKVMDEIRTKFGKNSILRGISYTNNATARY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHH
RNTLLGGHKA
HHHHCCCCCC
>Mature Secondary Structure
MFSLLGGVIVYDYSILPDRIILCVDLRSFYASVSCIKMGVDPLHTKLAVVGDVNRNGSIV
CCHHHCCHHEEECEECCCCEEEEEEHHHHHHHHHHHHHCCCHHHCEEEEEEECCCCCCEE
LAATPPLKAMGVKKLARLYEIPRQKDILIVNPIMGTYIKCSNYITKLALQYVPIEDFHQY
EEECCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SIDEFFMDITDSIHLFARNPNEFALQFKREIYEHTRIECTIGIAPNLLMSKVALDIEAKK
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCC
KKDGIAYWKYEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLAHYPLKYLKQSF
CCCCEEEEEECCCCCHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIGEELHLHSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRL
CCCCCEEEEECCCCCHHHHCCCCCCEEECCCCCEEEEECCCCCCCCEEEEECCHHHHHHH
RQQNKLAQTVQFSIGYSKSYSGGFSKTHTLSRPTNLTMDIYQVCLYFLHQQYTGEPIRSI
HHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
TISLTKLIGEGEEQISLFDNIIQREKEIKLTKVMDEIRTKFGKNSILRGISYTNNATARY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHH
RNTLLGGHKA
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]