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The map label for this gene is aroA [H]

Identifier: 118478280

GI number: 118478280

Start: 2798119

End: 2799408

Strand: Reverse

Name: aroA [H]

Synonym: BALH_2641

Alternate gene names: 118478280

Gene position: 2799408-2798119 (Counterclockwise)

Preceding gene: 118478281

Following gene: 118478279

Centisome position: 53.25

GC content: 39.61

Gene sequence:

>1290_bases
GTGAAGGAAAGAATAATACAACCTGTAAATAGCGGATTGAATGGCAATATTACAATCCCGGGTGATAAGTCCATTTCACA
CCGCGCTGTTATGTTCGGCGCGATTGCAGAAGGAAAAACGACAATTAAAGGTTTCTTGCCTGGTGCAGACTGTTTAAGTA
CGATTTCTTGTTTTAAAGAAATGGGAGTAGACATTGTGCAAAACGGTGATGAAGTCACTGTAGTTGGTAAAGGATTAGAA
GGTTTACAAGAACCGAAAGCTGTATTAGATGTTGGTAATTCTGGTACAACTATACGTTTAATGTCAGGAATTTTGGCAAA
TACACCATTTTTCTCTTGCGTACAAGGTGATGCGTCTATTGCAAAAAGACCGATGAAACGTGTAACAAATCCATTAAAAC
AAATGGGTGCAAACATTGATGGCCGCGAAGAAGGAACGTTTACACCGCTAACAATACGTGGTGGAGATTTAAAAGCAATT
GAATACAATTCGCCTGTAGCAAGCGCACAAGTGAAATCAGCTATTTTACTTGCAGGACTTCGTGCAGAAGGTGTAACAGC
TGTTACAGAACCACATATTTCTCGCGATCATACGGAAAGAATGCTTGAAGCATTTGGCGTCAAAGTAACTCGCGAAGGGA
AAACAGTGAAACTAGCAGGTGGACAAAAGTTAACAGCGACAGACGTTCAAGTGCCCGGTGACGTATCATCAGCTGCATTT
TTCTTAGTAGCGGGCGCGATTATTCCAAATAGTAAACTAGTATTAGAAAATGTAGGGATGAATCCAACTCGTACAGGTAT
TATTGATGTTTTAGAGAAGATGGGTGCTACGTTCACTGTAGAGCCAATTAACGAAGGAGCATCAGAACCAGCTGCAAATA
TTACAATTGAAACATCTTCATTAAAAGGAATCGAAATCGGTGGAGATATTATCCCTAGATTAATCGATGAAATTCCTGTA
ATTGCATTAGCGGCAACGCAAGCGGAAGGAATTACAGTTATTAAAGATGCACACGAATTAAAAGTAAAAGAAACAAACCG
TATTGATACAGTTGTTGCAGAGTTAACGAAACTAGGAGCTCGTATAGAAGCAACCGATGACGGAATGATCATTTACGGAA
AATCAGCTCTAAAAGGTAATACAGTTAATAGTTACGGTGATCACCGCATCGGAATGATGCTTGCGATTGCTGGATGTATC
GCAGAAGGAAAAACAATAATTGAAGACGCAGAAGCAGTAGGCGTATCATATCCTACGTTCTTCGAAGAACTTCAAAAGTT
AACTAAATAA

Upstream 100 bases:

>100_bases
ATTAGCTTCCAGCGAGAAGAAGATCGTATGAAAGCAAAGCTAGCGCTTGGAGAAGAAAAATACCAAACTTATGAAACAAT
TTAAATGAGAAGGTGAAAAT

Downstream 100 bases:

>100_bases
ATTGATGAGAAGCAGATACAGGATGTATCTGCTTTTTTATATTGAATTTGTGTCGTTAAGTCTATATAATTTCATTCACC
GCACTTTAATATTTTAAATT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKERIIQPVNSGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYNSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCI
AEGKTIIEDAEAVGVSYPTFFEELQKLTK

Sequences:

>Translated_429_residues
MKERIIQPVNSGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYNSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCI
AEGKTIIEDAEAVGVSYPTFFEELQKLTK
>Mature_429_residues
MKERIIQPVNSGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYNSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCI
AEGKTIIEDAEAVGVSYPTFFEELQKLTK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=442, Percent_Identity=27.8280542986425, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320332, Length=457, Percent_Identity=26.2582056892779, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45225; Mature: 45225

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERIIQPVNSGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKE
CCCCHHHHHCCCCCCCEECCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHH
MGVDIVQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASI
CCCCEEECCCEEEEEECCCCCHHCCHHHEECCCCCCEEHHHHHHHHCCCCCEEECCCHHH
AKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYNSPVASAQVKSAILLAGL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCC
RAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
CCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCEEEEECCCEEEEECEECCCCCHHHHH
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECC
LKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGA
CCCEEECHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHEEECCCCHHHHHHHHHHHHCC
RIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCIAEGKTIIEDAEAVGVSYPTF
EEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
FEELQKLTK
HHHHHHHCC
>Mature Secondary Structure
MKERIIQPVNSGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKE
CCCCHHHHHCCCCCCCEECCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHH
MGVDIVQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASI
CCCCEEECCCEEEEEECCCCCHHCCHHHEECCCCCCEEHHHHHHHHCCCCCEEECCCHHH
AKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYNSPVASAQVKSAILLAGL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCC
RAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
CCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCEEEEECCCEEEEECEECCCCCHHHHH
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECC
LKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGA
CCCEEECHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHEEECCCCHHHHHHHHHHHHCC
RIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCIAEGKTIIEDAEAVGVSYPTF
EEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
FEELQKLTK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA