Click here to switch to the map view.

The map label for this gene is blyA [H]

Identifier: 118477889

GI number: 118477889

Start: 2391195

End: 2391713

Strand: Direct

Name: blyA [H]

Synonym: BALH_2234

Alternate gene names: 118477889

Gene position: 2391195-2391713 (Clockwise)

Preceding gene: 118477888

Following gene: 118477890

Centisome position: 45.49

GC content: 34.87

Gene sequence:

>519_bases
ATGCGTTGGTACACCAATAACGTTTACGTCCATATCAAAAAAGACGGCAACAAAGAATACTTGAAAAAAGATGAATTTAA
GCGCAAAACAGATGGAATTGCTTTTATTGAAGGATACAATGTGAATTTACGTAAAGGACCTGGTACAAGCTATTCTAAGA
TTCGTCAGCTAAATAAACCGGAATCTTATGTTGTATGGGCTGAAAAGGATGGTTGGTTAAATCTTGGTGATGAACAATGG
GTTAAGGACGATCCATCTTATGTAAAGTTAAGTAAGAAAAGCACTGTGGATTCATCAATTGTAGGTAAGCGTGTTGTTTC
TAAAGTTAATAATTTACGATTTTATGATGCTCCATCTTGGCGGAATAAAGATGTTGCTGGATCTGTAGATACAGGATTAG
GTTTCACAATCGATGCGAAAGTAAATGTTAACGGTTCACCGCAATATAAAGTACACAATAGCAAAGGAAAAACATACTAT
ATTAAGACAAGTGAAGCCTATGTGTATGTAGTAAAGTAA

Upstream 100 bases:

>100_bases
TGTTGTATATCCGTAATCCAAAGGCAATACATTCTCTTTAGCTCCAAGAGTTGAAACGTTATTTGCAAACAATCGTATTA
TTTTTGGAGATAATCCATTA

Downstream 100 bases:

>100_bases
TTAAAAAGCTGACTATAATTAGTCAGCTTTTTGTATACTATAATCTAGTATTTATCAATCCCAAAGACATGTTCTTTGCC
TTTAAGCTGGCACTGAAAAA

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Autolysin; Cell wall hydrolase [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MRWYTNNVYVHIKKDGNKEYLKKDEFKRKTDGIAFIEGYNVNLRKGPGTSYSKIRQLNKPESYVVWAEKDGWLNLGDEQW
VKDDPSYVKLSKKSTVDSSIVGKRVVSKVNNLRFYDAPSWRNKDVAGSVDTGLGFTIDAKVNVNGSPQYKVHNSKGKTYY
IKTSEAYVYVVK

Sequences:

>Translated_172_residues
MRWYTNNVYVHIKKDGNKEYLKKDEFKRKTDGIAFIEGYNVNLRKGPGTSYSKIRQLNKPESYVVWAEKDGWLNLGDEQW
VKDDPSYVKLSKKSTVDSSIVGKRVVSKVNNLRFYDAPSWRNKDVAGSVDTGLGFTIDAKVNVNGSPQYKVHNSKGKTYY
IKTSEAYVYVVK
>Mature_172_residues
MRWYTNNVYVHIKKDGNKEYLKKDEFKRKTDGIAFIEGYNVNLRKGPGTSYSKIRQLNKPESYVVWAEKDGWLNLGDEQW
VKDDPSYVKLSKKSTVDSSIVGKRVVSKVNNLRFYDAPSWRNKDVAGSVDTGLGFTIDAKVNVNGSPQYKVHNSKGKTYY
IKTSEAYVYVVK

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Involved in prophage SP-beta-mediated cell lysis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502 [H]

Pfam domain/function: PF01510 Amidase_2 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 19748; Mature: 19748

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWYTNNVYVHIKKDGNKEYLKKDEFKRKTDGIAFIEGYNVNLRKGPGTSYSKIRQLNKP
CEEECCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCCHHHHHHCCCC
ESYVVWAEKDGWLNLGDEQWVKDDPSYVKLSKKSTVDSSIVGKRVVSKVNNLRFYDAPSW
CEEEEEECCCCCEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEEECCCC
RNKDVAGSVDTGLGFTIDAKVNVNGSPQYKVHNSKGKTYYIKTSEAYVYVVK
CCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCEEEEEECCEEEEEEC
>Mature Secondary Structure
MRWYTNNVYVHIKKDGNKEYLKKDEFKRKTDGIAFIEGYNVNLRKGPGTSYSKIRQLNKP
CEEECCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCCHHHHHHCCCC
ESYVVWAEKDGWLNLGDEQWVKDDPSYVKLSKKSTVDSSIVGKRVVSKVNNLRFYDAPSW
CEEEEEECCCCCEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEEECCCC
RNKDVAGSVDTGLGFTIDAKVNVNGSPQYKVHNSKGKTYYIKTSEAYVYVVK
CCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCEEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579063; 9384377 [H]