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The map label for this gene is mtaD [H]

Identifier: 118477326

GI number: 118477326

Start: 1789247

End: 1790572

Strand: Direct

Name: mtaD [H]

Synonym: BALH_1643

Alternate gene names: 118477326

Gene position: 1789247-1790572 (Clockwise)

Preceding gene: 118477325

Following gene: 118477327

Centisome position: 34.03

GC content: 37.56

Gene sequence:

>1326_bases
TTGAAAGGGGAAATACTTTTGAAAACAACTTATGTAAACGCTACAATTGTAACGATGAATGAACAAAACGAAGTGATAGA
AAATGGATATATCATTGTAGAAAATGATAAAATTATAGATGTAAATAGCGGAGAATTCGCTAGTGATTTTGAAGTAGATG
AAGTAATTGACATGAAAGGAAAGTGGGTTTTACCAGGGCTTGTAAATACACATACACACGTTGTAATGAGTCTCTTAAGA
GGTATTGGTGATGATATGTTATTACAACCATGGCTTGAGACGAGAATTTGGCCACTTGAAAGTCAATTTACTCCCCAAAT
TGCGGTCGCTAGTACGGAATTAGGATTACTTGAAATGGTGAAAAGCGGTACAACATCATTCTCGGATATGTTTAATCCAA
TTGGAGTAGATCAAGATGCAATTATGGAAACGGTATCAAGAAGCGGAATGCGAGCTGCTGTTTCAAGAACTTTATTTAGC
TTTGGAACGAAAGAAGATGAAAAGAAAGCAATTGAAGAAGCTGAGAAATATGTGAAGCGTTATTATAACGAAAGTGGTAT
GTTAACTACGATGGTTGCACCGCATAGTCCATATACATGTAGTACAGAACTGTTAGAAGAGTGTGCACGTATTGCAGTAG
AAAATCAAACGATGGTTCATATTCACCTTTCCGAAACAGAGCGTGAAGTACGTGATATTGAAGCGCAGTACGGAAAACGT
CCAGTAGAATATGCGGCAAGTTGCGGATTGTTTAAACGATCGACAGTGATTGCACACGGTGTAGTATTAAATGACAATGA
GCGTGCATTTTTAGCAGAACATGACGTTCGAGTAGCTCATAATCCGAATAGTAATTTAAAACTAGGGTCTGGTATAGCGA
ATGTAAAAGCGATGTTAGAAGCAGGAATAAAAGTAGGAATTGCAACAGATAGTGTTGCATCTAACAATAATTTAGATATG
TTTGAAGAAATGCGCATAGCGACTTTACTACAAAAAGGTATTCACCAAGATGCAACAGCTTTACCAGTTGAAACAGCTCT
TACACTTGCGACAAAAGGAGCTGCTGAAGTAATCGGCATGAAACAAACAGGATCACTTGAGGTTGGAAAGTGTGCGGATT
TTATTACGATTGACCCGTCTAATAAGCCGCATTTACAACCAGCGGATGAAGTGCTATCACACCTTGTATATGCTGCTAGT
GGAAAAGATATAAGTGATGTAATCATTAACGGAAAACGTGTCGTTTGGAATGGCGAATGTAAAACGTTAGATGAAGAGCG
TATTATATTTGAAGCAAGTCGTTATAAACGAGGTTTGCAAAGATAA

Upstream 100 bases:

>100_bases
TGAAGAAAAAGATAACGAAAGAATTGAAATTATCTTTTGACTCTTAATCTTTAATAAGTTACTATAATGGTGGTAACTTA
TTAAAGGGAACTTCATAGAG

Downstream 100 bases:

>100_bases
GTATTTTCAGGCTGTGGAGAAAGTCTTCTCCACAGCCTGTTTTTGTGTGTGAACCTTTTTGGTGCCAACATTGATAAAAA
GAGGGAAAGGATAGATTTTT

Product: chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKGEILLKTTYVNATIVTMNEQNEVIENGYIIVENDKIIDVNSGEFASDFEVDEVIDMKGKWVLPGLVNTHTHVVMSLLR
GIGDDMLLQPWLETRIWPLESQFTPQIAVASTELGLLEMVKSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFS
FGTKEDEKKAIEEAEKYVKRYYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETEREVRDIEAQYGKR
PVEYAASCGLFKRSTVIAHGVVLNDNERAFLAEHDVRVAHNPNSNLKLGSGIANVKAMLEAGIKVGIATDSVASNNNLDM
FEEMRIATLLQKGIHQDATALPVETALTLATKGAAEVIGMKQTGSLEVGKCADFITIDPSNKPHLQPADEVLSHLVYAAS
GKDISDVIINGKRVVWNGECKTLDEERIIFEASRYKRGLQR

Sequences:

>Translated_441_residues
MKGEILLKTTYVNATIVTMNEQNEVIENGYIIVENDKIIDVNSGEFASDFEVDEVIDMKGKWVLPGLVNTHTHVVMSLLR
GIGDDMLLQPWLETRIWPLESQFTPQIAVASTELGLLEMVKSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFS
FGTKEDEKKAIEEAEKYVKRYYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETEREVRDIEAQYGKR
PVEYAASCGLFKRSTVIAHGVVLNDNERAFLAEHDVRVAHNPNSNLKLGSGIANVKAMLEAGIKVGIATDSVASNNNLDM
FEEMRIATLLQKGIHQDATALPVETALTLATKGAAEVIGMKQTGSLEVGKCADFITIDPSNKPHLQPADEVLSHLVYAAS
GKDISDVIINGKRVVWNGECKTLDEERIIFEASRYKRGLQR
>Mature_441_residues
MKGEILLKTTYVNATIVTMNEQNEVIENGYIIVENDKIIDVNSGEFASDFEVDEVIDMKGKWVLPGLVNTHTHVVMSLLR
GIGDDMLLQPWLETRIWPLESQFTPQIAVASTELGLLEMVKSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFS
FGTKEDEKKAIEEAEKYVKRYYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETEREVRDIEAQYGKR
PVEYAASCGLFKRSTVIAHGVVLNDNERAFLAEHDVRVAHNPNSNLKLGSGIANVKAMLEAGIKVGIATDSVASNNNLDM
FEEMRIATLLQKGIHQDATALPVETALTLATKGAAEVIGMKQTGSLEVGKCADFITIDPSNKPHLQPADEVLSHLVYAAS
GKDISDVIINGKRVVWNGECKTLDEERIIFEASRYKRGLQR

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=381, Percent_Identity=27.5590551181102, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI1789249, Length=405, Percent_Identity=26.1728395061728, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082177, Length=444, Percent_Identity=25.4504504504505, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17540282, Length=407, Percent_Identity=25.0614250614251, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6319963, Length=351, Percent_Identity=28.2051282051282, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24643849, Length=425, Percent_Identity=27.0588235294118, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 48741; Mature: 48741

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGEILLKTTYVNATIVTMNEQNEVIENGYIIVENDKIIDVNSGEFASDFEVDEVIDMKG
CCCCEEEEEEEEEEEEEEECCCCHHHHCCEEEEECCEEEECCCCCCCCCCCHHHHHCCCC
KWVLPGLVNTHTHVVMSLLRGIGDDMLLQPWLETRIWPLESQFTPQIAVASTELGLLEMV
CEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHH
KSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFSFGTKEDEKKAIEEAEKYVKR
HCCCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
YYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETEREVRDIEAQYGKR
HHCCCCCEEEEECCCCCCCCHHHHHHHHHHHEECCCEEEEEEECCHHHHHHHHHHHHCCC
PVEYAASCGLFKRSTVIAHGVVLNDNERAFLAEHDVRVAHNPNSNLKLGSGIANVKAMLE
HHHHHHHCCCHHCCEEEEEEEEEECCCCEEEEECCEEEEECCCCCCEECCCHHHHHHHHH
AGIKVGIATDSVASNNNLDMFEEMRIATLLQKGIHQDATALPVETALTLATKGAAEVIGM
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHEEE
KQTGSLEVGKCADFITIDPSNKPHLQPADEVLSHLVYAASGKDISDVIINGKRVVWNGEC
CCCCCEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHEECCCEEEECCCC
KTLDEERIIFEASRYKRGLQR
CCCCCHHHEEEHHHHHHCCCC
>Mature Secondary Structure
MKGEILLKTTYVNATIVTMNEQNEVIENGYIIVENDKIIDVNSGEFASDFEVDEVIDMKG
CCCCEEEEEEEEEEEEEEECCCCHHHHCCEEEEECCEEEECCCCCCCCCCCHHHHHCCCC
KWVLPGLVNTHTHVVMSLLRGIGDDMLLQPWLETRIWPLESQFTPQIAVASTELGLLEMV
CEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHH
KSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFSFGTKEDEKKAIEEAEKYVKR
HCCCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
YYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETEREVRDIEAQYGKR
HHCCCCCEEEEECCCCCCCCHHHHHHHHHHHEECCCEEEEEEECCHHHHHHHHHHHHCCC
PVEYAASCGLFKRSTVIAHGVVLNDNERAFLAEHDVRVAHNPNSNLKLGSGIANVKAMLE
HHHHHHHCCCHHCCEEEEEEEEEECCCCEEEEECCEEEEECCCCCCEECCCHHHHHHHHH
AGIKVGIATDSVASNNNLDMFEEMRIATLLQKGIHQDATALPVETALTLATKGAAEVIGM
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHEEE
KQTGSLEVGKCADFITIDPSNKPHLQPADEVLSHLVYAASGKDISDVIINGKRVVWNGEC
CCCCCEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHEECCCEEEECCCC
KTLDEERIIFEASRYKRGLQR
CCCCCHHHEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA