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The map label for this gene is cat1 [H]

Identifier: 118477323

GI number: 118477323

Start: 1786637

End: 1788151

Strand: Direct

Name: cat1 [H]

Synonym: BALH_1640

Alternate gene names: 118477323

Gene position: 1786637-1788151 (Clockwise)

Preceding gene: 118477322

Following gene: 118477324

Centisome position: 33.99

GC content: 38.61

Gene sequence:

>1515_bases
ATGGAGAATAATTTGGATAGAATTAGGGATCAACGTCTGAAAGATCGCGTAGTTACACCTGAAGAAGCAGCTTCATGGAT
TGAAAGTGGAATGACTTTAGGCTTAAGTGGGTTTACACGTGCAGGTGATGTGAAAGCAGTCCCATTTGCGCTTGTAAATC
GAGTTAAGAATGATACATCTTTTAAAGTAAATGTATTTACTGGTGCTTCTTTAGGTTCTGATGTAGATAAATTATTTGCG
GAAGCAGGAATTTTAGGGAAAAGATTGCCTTTCCAAGCTGATGCGACTATGCGCAAAGGAATTAATAACGGAGATTTTTT
ATTTGTGGACCAGCACTTATCTCATACAGCAGAGTTACTTCGCGCTGACGTTATGGATGTAGATTTTGCTATTTTGGAAG
CGGTTGCGATTACTGAAGATGGTATGATTATTCCAACAACTTCAATAGGAAATTCTTTAGCGTTTTCTTTAAATGCTAAG
TCCATCATTATTGAAATGAATATGGCCCAATCCGAGCAATTAGAAGGACTGCATGATTTATATGAACCAGGTAAGCAAGG
AGAAAGGCTTCCAATTCCGATTGTGAAAACGGATGATCGAATTGGAACGATTGGCATTCCGATTGATGTTGACAAAGTGA
AGGGGATTGTATTTACAAACCAATTAGATTCGCCATCAACAATTGTCCCTCCAGATGAAGAAACTGTTATTATGGCACAA
CATTTAATAGAATTCCTTCGAAAAGAAGTCGAAGTAGGCCGATTAACAAATCGTTTAGCGCCGCTACAATCGGGAATTGG
TTCAGTTGCCAATGCAGTTCTTCATGGAATGTTAGATTCTGAGTTTGAAGATTTAGAAGTATATTCTGAGGTTTTACAGG
ATGCTGTCTTTGATCTTATGGATGCTGGAAAAGTCAATTTTGCTTCATGCTGCTCGATCACACTTTCTGAGGAGAAAATG
CAAAAAGTATTTTCCAACTTTGAAAAATATCGTGACAAATTAATGATGCGCCCGCAAGAGATTTCCAATCATCCTGAGAT
CATTCGCCGCCTCGGATTAATCTCGATTAATACTGCTTTAGAATTAGATATATACGGAAATGTGAACTCTACTCACGTTT
TAGGTACAAAAATGATGAACGGTATCGGTGGTTCTGGTGACTTTGCAAGAAATGCACGCCTAGCTATCTTTGTTACGAAA
TCGATTGCGAAAGGTGGTAACATTTCAAGTATCGTTCCTTTCGCCTCACATATAGACCATACGGAACATGATGTAGATGT
TATCGTCACTGAGCAAGGATATGCTGACTTAAGAGGACTTGCGCCAAGTGAAAGAGTGGAACTCGTTATTGAGAATTGTG
CACATCCAATGTATCGTGATCAACTACGAGCTTATTATGAGGAAGCGAAAACAAGAGGTGGACAAACTCCTCATATTTTA
GAGAAAGCTTTTTCTTGGCATACGAATTATGCTAAAAATGGAACGATGCTTGAAGAGGTAGTAGAAACTGTATAG

Upstream 100 bases:

>100_bases
CTGTTTTATCTGAATTTTTGCCATTGTATACTGAAATCCCTATTTGGATACTGTTAAAGTGTAAAATAATTATGAATATT
CACAGGAAGAGGGATTACAT

Downstream 100 bases:

>100_bases
AAATATAAGAATGATTCTTAGAATAATATGCTATAAAGATTGAAAGAAAAGAACGCCAATTTTCAGGAATGGCGTTTTTT
TTCTTTTAAAAAATTATTAT

Product: succinyl-CoA: coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVFTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSEQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVDKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFASHIDHTEHDVDVIVTEQGYADLRGLAPSERVELVIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEEVVETV

Sequences:

>Translated_504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVFTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSEQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVDKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFASHIDHTEHDVDVIVTEQGYADLRGLAPSERVELVIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEEVVETV
>Mature_504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVFTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSEQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVDKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFASHIDHTEHDVDVIVTEQGYADLRGLAPSERVELVIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEEVVETV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=41.9753086419753, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17538151, Length=397, Percent_Identity=25.9445843828715, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319456, Length=518, Percent_Identity=41.6988416988417, Blast_Score=397, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55625; Mature: 55625

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTS
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNVFTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSEQLEGLHDL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHH
YEPGKQGERLPIPIVKTDDRIGTIGIPIDVDKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCEEEECCCCEEEEECCEEHHHHCEEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFASHIDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCCCHHHHHHHHCCC
TEHDVDVIVTEQGYADLRGLAPSERVELVIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
CCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKNGTMLEEVVETV
HHHHHHCCCCCCCCHHHHHHHHHC
>Mature Secondary Structure
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTS
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNVFTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSEQLEGLHDL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHH
YEPGKQGERLPIPIVKTDDRIGTIGIPIDVDKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCEEEECCCCEEEEECCEEHHHHCEEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFASHIDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCCCHHHHHHHHCCC
TEHDVDVIVTEQGYADLRGLAPSERVELVIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
CCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKNGTMLEEVVETV
HHHHHHCCCCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]