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The map label for this gene is 118477221

Identifier: 118477221

GI number: 118477221

Start: 1672841

End: 1674151

Strand: Direct

Name: 118477221

Synonym: BALH_1527

Alternate gene names: NA

Gene position: 1672841-1674151 (Clockwise)

Preceding gene: 118477220

Following gene: 118477222

Centisome position: 31.82

GC content: 35.77

Gene sequence:

>1311_bases
ATGTTTATTACTTCTGCAACATATAGAGCAAAAACGAAAAGGGGTAGCATGATGAGGGTAGAAGTATGGGGAGGAGCGGG
AGAATACGGTCGCTCCTGCTACTTCGTAAAAAATAAAGAGACAAAAATATTATTTGATTGTGGTATTAATCGATCATATG
AGGATAGTTATCCAAAAATAGAGCGGGAAGTTGTACCGTTTTTAGATGCAGTATTTTTATCACATATTCATGAAGATCAT
ACGATGGGCTTACCTTTATTAGCGAAGTATGGATATAAGAAAAAAATCTGGACGACCCGTTATACGAAGGAGCAACTTCC
TGCTTATTATGAAAAATGGAGAAACTACAATTTGGCGCAAGGATGGCATTTACCTTATAACGACCAAAATGTTACAGATT
TGAATTATGTATATATTGATGAGATAAGTAATCCGAATGAATGGATACAGATTACACCTACATTGCGTTTTCAATGGGGG
TATAGTGGGCATGTATTAGGGGCTGTTTGGTTTTTAGTGGATATGAGCCATACATATGTATTTTATTCTGGCGATTATTC
AGCAGAGTCTAACATACTTCGAGCTAATTTACCTGAGAAATTGCGTGGCGATATAAAAGTTGCAATTGTGGATGCCGCTT
ATCATACTGATGATGTTTCACAATATGAACGAGTAAACGAACTATGTACAGAAATTGAACGAGCTGCGGGGAATAAAGGG
GTAGCATTACTACCATTGCCACCCCTTGGTAGGGCGCAAGATATCGTATTGTATTTATATGAAAAATATAAAGAATTTCC
CATTATAGTAGATCAGGAAATTTTAGATGGATTTGACGAGATGTTCGTATATAAAGATTGGATCAAAAAGAATAAAGAAC
TTGAAGAGCTAATGGAGAGTTTAAAAAGAAACATAATAGTTATGGATGATGATGGCGGTACGCAACATAGTTATGGAATA
GTTGTAATGAGTGATGCGAATATGCAAACGAAACGGGCTCAGTTATATTATGAACAAATTCGGCATGAAGAAAGAAATTC
TATTATCTTTACTGGGCATGTTGCTAAAGGGAGTTTTGCAGAAAAAGTTTTGAAAGAACGTATAGGTAAAGAATGTAGGG
TGAAGCAAGTTCCATATAAAGTTCACCAAAGTATAAGAGATGTGAAAGCGATGTTAAATGCATTATTACCGGAACATACG
GTGTTAGTACACGCTTTAAAAGAGGATACAGATCGATTACAGAAAAAGCTGAGCACGGCAGGGTATGAAAATGTATATTC
ACTTACTATGGAACGTATAGAAGTTATTTAA

Upstream 100 bases:

>100_bases
CAGTAGAAACGTCAGCAACATTTATTTTTGCTCAATTTGAACAAGGAGAAGTCTCTATTGGTATGGCGATGGCTGTCGTT
TCAGTTGGACTTACAACATT

Downstream 100 bases:

>100_bases
AATGTAAAGGAGATAGGTATATGAAAAAAGTATTTGTATTCGTAAGTATTTTCTTTTGTTGTTTCCTTTATAACGTTAAG
GAAGGGTTTGCTGCCAGTCC

Product: Zn-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MFITSATYRAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNLAQGWHLPYNDQNVTDLNYVYIDEISNPNEWIQITPTLRFQWG
YSGHVLGAVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQYERVNELCTEIERAAGNKG
VALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKKNKELEELMESLKRNIIVMDDDGGTQHSYGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKQVPYKVHQSIRDVKAMLNALLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI

Sequences:

>Translated_436_residues
MFITSATYRAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNLAQGWHLPYNDQNVTDLNYVYIDEISNPNEWIQITPTLRFQWG
YSGHVLGAVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQYERVNELCTEIERAAGNKG
VALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKKNKELEELMESLKRNIIVMDDDGGTQHSYGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKQVPYKVHQSIRDVKAMLNALLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
>Mature_436_residues
MFITSATYRAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNLAQGWHLPYNDQNVTDLNYVYIDEISNPNEWIQITPTLRFQWG
YSGHVLGAVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQYERVNELCTEIERAAGNKG
VALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKKNKELEELMESLKRNIIVMDDDGGTQHSYGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKQVPYKVHQSIRDVKAMLNALLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=426, Percent_Identity=26.056338028169, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI33300633, Length=439, Percent_Identity=22.5512528473804, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566029, Length=440, Percent_Identity=23.1818181818182, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32564696, Length=438, Percent_Identity=22.1461187214612, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323307, Length=438, Percent_Identity=22.8310502283105, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24648013, Length=454, Percent_Identity=24.8898678414097, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21358523, Length=434, Percent_Identity=23.2718894009217, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 50779; Mature: 50779

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFITSATYRAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKI
CEECCCCHHHHCCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHH
EREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNLAQ
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCC
GWHLPYNDQNVTDLNYVYIDEISNPNEWIQITPTLRFQWGYSGHVLGAVWFLVDMSHTYV
CCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCEEE
FYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQYERVNELCTEIERAAGNKG
EEECCCCCCCCEEECCCCHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
VALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKKNKELEELMES
EEEEECCCCCCHHHHHHHHHHHHCCCCEEECHHHHCCHHHHHHHHHHHHCCHHHHHHHHH
LKRNIIVMDDDGGTQHSYGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFA
HHCCEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
EKVLKERIGKECRVKQVPYKVHQSIRDVKAMLNALLPEHTVLVHALKEDTDRLQKKLSTA
HHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GYENVYSLTMERIEVI
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFITSATYRAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKI
CEECCCCHHHHCCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHH
EREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNLAQ
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCC
GWHLPYNDQNVTDLNYVYIDEISNPNEWIQITPTLRFQWGYSGHVLGAVWFLVDMSHTYV
CCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCEEE
FYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQYERVNELCTEIERAAGNKG
EEECCCCCCCCEEECCCCHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
VALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKKNKELEELMES
EEEEECCCCCCHHHHHHHHHHHHCCCCEEECHHHHCCHHHHHHHHHHHHCCHHHHHHHHH
LKRNIIVMDDDGGTQHSYGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFA
HHCCEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
EKVLKERIGKECRVKQVPYKVHQSIRDVKAMLNALLPEHTVLVHALKEDTDRLQKKLSTA
HHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GYENVYSLTMERIEVI
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]