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The map label for this gene is chrR [H]

Identifier: 118477153

GI number: 118477153

Start: 1608612

End: 1609355

Strand: Direct

Name: chrR [H]

Synonym: BALH_1457

Alternate gene names: 118477153

Gene position: 1608612-1609355 (Clockwise)

Preceding gene: 118477152

Following gene: 118477154

Centisome position: 30.6

GC content: 36.96

Gene sequence:

>744_bases
GTGATTTTCATGAATGAAATGATACATAAAATGGAGCAACACGTTTCAGTTCGTAAATATAAAGAAGAGTCCATTCCGAA
AGATGTAGTAGAAAGAATGGTGCAAGCTGGGCAGCATGCTGCGTCCTCTCATTTTGTACAGGCCTATTCTGTTATATATG
TAACCGATCAAGACTTAAAGGCTAAACTAGCAGAGTTGTCTGGAAATCGACATGTGAAAGATTGCGCAGCATTCTTTGTT
TGTTGTGCAGATTTAAAACGACTTGAAATGGCATGTGAAAAACATGGTACAGAGATAAAGCATGAGGGAGTAGAAGACTT
TATCGTAGCAACGGTAGATGCTTCACTTTTTGCGCAAAACTTAGCGTTAGCAGCAGAATCGTTAGGATACGGTATTTGTT
ATATTGGTGGTATTCGTAATAATCCGAGAGAAGTGAGCGAATTGCTTCATTTACCGGATAAAGTATATCCTGTATTCGGA
ATGACAGTCGGTGTACCAGATGAAGATCATGGAGTAAAACCACGCTTACCAGTAGCAGCAATCCTTCATGAAAATGAATA
TGATGAAAAGAAATATGATGAATTACTAAACGAATACGATGAAACGATGAGCGCGTATTATAAAGGAAGATCATCAAACA
AGAAAAGCGTAACATGGACGGAATCAATGAGTTCGTTTATGTCTAAAGAAAAAAGAATGCATATGAAAGAGTTTTTAAGT
GAAAAAGGACTTAATAAGAAATGA

Upstream 100 bases:

>100_bases
TTAAAAAGAGCAATTCAAAAAAGAATTGCTCTTTTTGTGCTTATAAGTTGTGAATATTGGAAAAGATATGTTAATTTCTC
ATTAGGAAGAGAAAAAAGGA

Downstream 100 bases:

>100_bases
ATAAAAAGGCAGACCTACATGTAGGTCTGCCTTTTTTGGAGGAGAAATATGATTGTTTTCGAATAAGTATAGAAGGAGGA
GATAATATGAAAAAAGCTTT

Product: oxygen-insensitive NADPH nitroreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MIFMNEMIHKMEQHVSVRKYKEESIPKDVVERMVQAGQHAASSHFVQAYSVIYVTDQDLKAKLAELSGNRHVKDCAAFFV
CCADLKRLEMACEKHGTEIKHEGVEDFIVATVDASLFAQNLALAAESLGYGICYIGGIRNNPREVSELLHLPDKVYPVFG
MTVGVPDEDHGVKPRLPVAAILHENEYDEKKYDELLNEYDETMSAYYKGRSSNKKSVTWTESMSSFMSKEKRMHMKEFLS
EKGLNKK

Sequences:

>Translated_247_residues
MIFMNEMIHKMEQHVSVRKYKEESIPKDVVERMVQAGQHAASSHFVQAYSVIYVTDQDLKAKLAELSGNRHVKDCAAFFV
CCADLKRLEMACEKHGTEIKHEGVEDFIVATVDASLFAQNLALAAESLGYGICYIGGIRNNPREVSELLHLPDKVYPVFG
MTVGVPDEDHGVKPRLPVAAILHENEYDEKKYDELLNEYDETMSAYYKGRSSNKKSVTWTESMSSFMSKEKRMHMKEFLS
EKGLNKK
>Mature_247_residues
MIFMNEMIHKMEQHVSVRKYKEESIPKDVVERMVQAGQHAASSHFVQAYSVIYVTDQDLKAKLAELSGNRHVKDCAAFFV
CCADLKRLEMACEKHGTEIKHEGVEDFIVATVDASLFAQNLALAAESLGYGICYIGGIRNNPREVSELLHLPDKVYPVFG
MTVGVPDEDHGVKPRLPVAAILHENEYDEKKYDELLNEYDETMSAYYKGRSSNKKSVTWTESMSSFMSKEKRMHMKEFLS
EKGLNKK

Specific function: Reduction Of Nitroaromatic Compounds Using NADH. Reduces Nitrofurazone By A Ping-Pong Bi-Bi Mechanism Possibly To Generate A Two-Electron Transfer Product. Major Component Of The Oxygen- Insensitive Nitroreductase Activity In E.Coli. [C]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin oxidoreductase frp family [H]

Homologues:

Organism=Escherichia coli, GI1787075, Length=242, Percent_Identity=35.9504132231405, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016446
- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28093; Mature: 28093

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFMNEMIHKMEQHVSVRKYKEESIPKDVVERMVQAGQHAASSHFVQAYSVIYVTDQDLK
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHEEEEEEECHHHH
AKLAELSGNRHVKDCAAFFVCCADLKRLEMACEKHGTEIKHEGVEDFIVATVDASLFAQN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHH
LALAAESLGYGICYIGGIRNNPREVSELLHLPDKVYPVFGMTVGVPDEDHGVKPRLPVAA
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHCEEECCCCCCCCCCCCCCHHH
ILHENEYDEKKYDELLNEYDETMSAYYKGRSSNKKSVTWTESMSSFMSKEKRMHMKEFLS
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
EKGLNKK
HCCCCCC
>Mature Secondary Structure
MIFMNEMIHKMEQHVSVRKYKEESIPKDVVERMVQAGQHAASSHFVQAYSVIYVTDQDLK
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHEEEEEEECHHHH
AKLAELSGNRHVKDCAAFFVCCADLKRLEMACEKHGTEIKHEGVEDFIVATVDASLFAQN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHH
LALAAESLGYGICYIGGIRNNPREVSELLHLPDKVYPVFGMTVGVPDEDHGVKPRLPVAA
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHCEEECCCCCCCCCCCCCCHHH
ILHENEYDEKKYDELLNEYDETMSAYYKGRSSNKKSVTWTESMSSFMSKEKRMHMKEFLS
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
EKGLNKK
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA