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The map label for this gene is rnjA [H]

Identifier: 118477147

GI number: 118477147

Start: 1602309

End: 1604003

Strand: Direct

Name: rnjA [H]

Synonym: BALH_1451

Alternate gene names: 118477147

Gene position: 1602309-1604003 (Clockwise)

Preceding gene: 118477145

Following gene: 118477148

Centisome position: 30.48

GC content: 33.81

Gene sequence:

>1695_bases
GTGAAAGGGAGGTTTTATCATTTGAAGTCATTAAAAAACAACTTGTCTATCGTTGCTTTAGGTGGAGTAAATGAAATAGG
AAAAAATATGTACGCTATTCAATATGAAAATGATATTGTCGTTATTGATTGTGGATCTAAATTTCCAGATGAAAGTTTAT
TAGGAATTGATTTAATAATTCCAGACATCACATACTTACAAGAAAATAAAGAAAAAATTCGCGGGTTAGTCGTCACGCAT
GGGCATGAGGACCATATTGGCGGAATACCATATTTTTTAAAACAACTAAACGTACCAATCTATGCGACGAAGTTAACGTT
AGGTTTAATTGAAATTAAATTAAAAGAGCATAATCTTCAAAATGATACAGAATTAATCGTCATTCACGCAGAATCAGAAA
TTGATCTCGGTTCTATTAAGACGACATTTTTTAAAACGAATCATAGTATTCCAGATTGTCTCGGTATTGTGTTTCATACT
CGAGAAGGTAATGTAGTACATACCGGAGATTTTAAATTTGATTTAACACCAGTAAATAACCAACATCCTGATATTCATAA
AATGGCTAAAATAGGTAGCGAAGGTGTACTAGCTTTACTATCTGAAAGTACAAATGCAGAACGACCAGGTTTTACTCCAT
CAGAGAGATCGGTAGGAGAACGGATAGAGGAAATATTTATGAAAGCAAATAGAAAAGTAATTATTTCTACATTTGCTTCT
AATGTGAATCGTGTTCAGCAAATAGTTGAAGCTTGCATAAAAACAAATCGAAAATTGGCTTTGCTCGGGAGAAGTATGGT
AAATGTAGTAGAAGTTGCTCTAGAGAAAGGGTATTTACATATTCCAGACGGCATGTTAATTGAAGCGAGTGAAGTAAATC
GTTTAGATCCAAAGCAGGTAGCGATACTTTGTACAGGAAGTCAAGGAGAACCGATGGCAGCTTTAGCGCGGTTAGCTAGT
GGAAACTATAGGCAAGTGGATGTTTTACCAGAAGATACGGTTATTATAGCGGCAACGCCTATTCCGGGAAATGAACGTAA
CGTTTCACGAATTATAGATAATTTATTCGCATTAGGAGCAAAAGTAATATATGGATCAGGTAGTTCTACTGGAGTCCATG
TATCTGGTCATGCGTATCAAGAAGAATTGAAATTAATGCTCACTTTAATGAAACCTAAATATTTTATTCCAATTCATGGA
GAGTTTAGAATGCTACATCACCATAGTTTGTTAGCAGAATCAATTGGTGTTGAAAAAGAGAATATTTTTATCGTTCGTAA
TGGAGATGTTGTAGATATAAGTAATGAAGAGGCAATCCAATCTAGAAAAATACAGGCAGGAAATATATATGTAGATGGAT
TAGGAATTGGTGACGTTGGAAATGCCTTATTACGTGATCGAAAACAACTTTCAGAAGATGGAATGCTCGTTATAGTTATT
ACTTTTAATAAAGCGGATGGAGATATAATTTCAGGTCCTGATATTATATCTCGTGGATTTGTCTACGTTCGTGATTCAGA
AGAATTTTTGAAGGAATTAAATAAACTAGCTGTTATTACGATTAATAATTTAAAGAAAGAGAAAGTGAATAGCTGGGGTA
TTTTGAAAAGAGAAGTAAGAGAAGCTTTAGGGAAGTATATATATACGAATACGAAAAGAAAGCCGATGATTCTTCCTATA
ATAATAGAGGTGTAA

Upstream 100 bases:

>100_bases
ATATAAGAATAGTGTGTAAATTTTTATATGTATGAAATTGTATGAAGTCCTTTTTCATTACAAATAATAAAGCCTAAATA
CGATTTCACGAATTATAAAT

Downstream 100 bases:

>100_bases
TAATGAATAAAAAGAATTCTCGTATGGGAATTCTTTTTGTTTTAAAGACAGAATGAACATATAATGAAATAAATAGAAAT
GGAAGGAAATAAAAGATGTT

Product: Zn-dependent hydrolase

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MKGRFYHLKSLKNNLSIVALGGVNEIGKNMYAIQYENDIVVIDCGSKFPDESLLGIDLIIPDITYLQENKEKIRGLVVTH
GHEDHIGGIPYFLKQLNVPIYATKLTLGLIEIKLKEHNLQNDTELIVIHAESEIDLGSIKTTFFKTNHSIPDCLGIVFHT
REGNVVHTGDFKFDLTPVNNQHPDIHKMAKIGSEGVLALLSESTNAERPGFTPSERSVGERIEEIFMKANRKVIISTFAS
NVNRVQQIVEACIKTNRKLALLGRSMVNVVEVALEKGYLHIPDGMLIEASEVNRLDPKQVAILCTGSQGEPMAALARLAS
GNYRQVDVLPEDTVIIAATPIPGNERNVSRIIDNLFALGAKVIYGSGSSTGVHVSGHAYQEELKLMLTLMKPKYFIPIHG
EFRMLHHHSLLAESIGVEKENIFIVRNGDVVDISNEEAIQSRKIQAGNIYVDGLGIGDVGNALLRDRKQLSEDGMLVIVI
TFNKADGDIISGPDIISRGFVYVRDSEEFLKELNKLAVITINNLKKEKVNSWGILKREVREALGKYIYTNTKRKPMILPI
IIEV

Sequences:

>Translated_564_residues
MKGRFYHLKSLKNNLSIVALGGVNEIGKNMYAIQYENDIVVIDCGSKFPDESLLGIDLIIPDITYLQENKEKIRGLVVTH
GHEDHIGGIPYFLKQLNVPIYATKLTLGLIEIKLKEHNLQNDTELIVIHAESEIDLGSIKTTFFKTNHSIPDCLGIVFHT
REGNVVHTGDFKFDLTPVNNQHPDIHKMAKIGSEGVLALLSESTNAERPGFTPSERSVGERIEEIFMKANRKVIISTFAS
NVNRVQQIVEACIKTNRKLALLGRSMVNVVEVALEKGYLHIPDGMLIEASEVNRLDPKQVAILCTGSQGEPMAALARLAS
GNYRQVDVLPEDTVIIAATPIPGNERNVSRIIDNLFALGAKVIYGSGSSTGVHVSGHAYQEELKLMLTLMKPKYFIPIHG
EFRMLHHHSLLAESIGVEKENIFIVRNGDVVDISNEEAIQSRKIQAGNIYVDGLGIGDVGNALLRDRKQLSEDGMLVIVI
TFNKADGDIISGPDIISRGFVYVRDSEEFLKELNKLAVITINNLKKEKVNSWGILKREVREALGKYIYTNTKRKPMILPI
IIEV
>Mature_564_residues
MKGRFYHLKSLKNNLSIVALGGVNEIGKNMYAIQYENDIVVIDCGSKFPDESLLGIDLIIPDITYLQENKEKIRGLVVTH
GHEDHIGGIPYFLKQLNVPIYATKLTLGLIEIKLKEHNLQNDTELIVIHAESEIDLGSIKTTFFKTNHSIPDCLGIVFHT
REGNVVHTGDFKFDLTPVNNQHPDIHKMAKIGSEGVLALLSESTNAERPGFTPSERSVGERIEEIFMKANRKVIISTFAS
NVNRVQQIVEACIKTNRKLALLGRSMVNVVEVALEKGYLHIPDGMLIEASEVNRLDPKQVAILCTGSQGEPMAALARLAS
GNYRQVDVLPEDTVIIAATPIPGNERNVSRIIDNLFALGAKVIYGSGSSTGVHVSGHAYQEELKLMLTLMKPKYFIPIHG
EFRMLHHHSLLAESIGVEKENIFIVRNGDVVDISNEEAIQSRKIQAGNIYVDGLGIGDVGNALLRDRKQLSEDGMLVIVI
TFNKADGDIISGPDIISRGFVYVRDSEEFLKELNKLAVITINNLKKEKVNSWGILKREVREALGKYIYTNTKRKPMILPI
IIEV

Specific function: Cleaves the 5'-leader sequence of certain mRNAs. May play a role in maturation and stability of specific mRNAs. Is also required for the maturation of the 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 62663; Mature: 62663

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRFYHLKSLKNNLSIVALGGVNEIGKNMYAIQYENDIVVIDCGSKFPDESLLGIDLII
CCCCEEEHHHHCCCCEEEEECCHHHHCCCEEEEEECCCEEEEECCCCCCCCCCEEEEEEE
PDITYLQENKEKIRGLVVTHGHEDHIGGIPYFLKQLNVPIYATKLTLGLIEIKLKEHNLQ
CCHHHHHCCHHHHCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEEEEEEEEEEECCCCC
NDTELIVIHAESEIDLGSIKTTFFKTNHSIPDCLGIVFHTREGNVVHTGDFKFDLTPVNN
CCCEEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEECCCEEEEEEECCC
QHPDIHKMAKIGSEGVLALLSESTNAERPGFTPSERSVGERIEEIFMKANRKVIISTFAS
CCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHH
NVNRVQQIVEACIKTNRKLALLGRSMVNVVEVALEKGYLHIPDGMLIEASEVNRLDPKQV
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCEE
AILCTGSQGEPMAALARLASGNYRQVDVLPEDTVIIAATPIPGNERNVSRIIDNLFALGA
EEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
KVIYGSGSSTGVHVSGHAYQEELKLMLTLMKPKYFIPIHGEFRMLHHHSLLAESIGVEKE
EEEEECCCCCCEEEECHHHHHHHHHHHHHHCCCEEEEECCCEEEEHHHHHHHHHHCCCCC
NIFIVRNGDVVDISNEEAIQSRKIQAGNIYVDGLGIGDVGNALLRDRKQLSEDGMLVIVI
CEEEEECCCEEECCCHHHHHHCCEEECCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEE
TFNKADGDIISGPDIISRGFVYVRDSEEFLKELNKLAVITINNLKKEKVNSWGILKREVR
EEECCCCCEECCCCHHHCCEEEEECCHHHHHHHCCEEEEEECCCCHHHCCCCCHHHHHHH
EALGKYIYTNTKRKPMILPIIIEV
HHHHHHEEECCCCCCEEEEEEEEC
>Mature Secondary Structure
MKGRFYHLKSLKNNLSIVALGGVNEIGKNMYAIQYENDIVVIDCGSKFPDESLLGIDLII
CCCCEEEHHHHCCCCEEEEECCHHHHCCCEEEEEECCCEEEEECCCCCCCCCCEEEEEEE
PDITYLQENKEKIRGLVVTHGHEDHIGGIPYFLKQLNVPIYATKLTLGLIEIKLKEHNLQ
CCHHHHHCCHHHHCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEEEEEEEEEEECCCCC
NDTELIVIHAESEIDLGSIKTTFFKTNHSIPDCLGIVFHTREGNVVHTGDFKFDLTPVNN
CCCEEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEECCCEEEEEEECCC
QHPDIHKMAKIGSEGVLALLSESTNAERPGFTPSERSVGERIEEIFMKANRKVIISTFAS
CCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHH
NVNRVQQIVEACIKTNRKLALLGRSMVNVVEVALEKGYLHIPDGMLIEASEVNRLDPKQV
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCEE
AILCTGSQGEPMAALARLASGNYRQVDVLPEDTVIIAATPIPGNERNVSRIIDNLFALGA
EEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
KVIYGSGSSTGVHVSGHAYQEELKLMLTLMKPKYFIPIHGEFRMLHHHSLLAESIGVEKE
EEEEECCCCCCEEEECHHHHHHHHHHHHHHCCCEEEEECCCEEEEHHHHHHHHHHCCCCC
NIFIVRNGDVVDISNEEAIQSRKIQAGNIYVDGLGIGDVGNALLRDRKQLSEDGMLVIVI
CEEEEECCCEEECCCHHHHHHCCEEECCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEE
TFNKADGDIISGPDIISRGFVYVRDSEEFLKELNKLAVITINNLKKEKVNSWGILKREVR
EEECCCCCEECCCCHHHCCEEEEECCHHHHHHHCCEEEEEECCCCHHHCCCCCHHHHHHH
EALGKYIYTNTKRKPMILPIIIEV
HHHHHHEEECCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]