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The map label for this gene is cpnA [H]

Identifier: 118476837

GI number: 118476837

Start: 1277795

End: 1278583

Strand: Direct

Name: cpnA [H]

Synonym: BALH_1124

Alternate gene names: 118476837

Gene position: 1277795-1278583 (Clockwise)

Preceding gene: 118476836

Following gene: 118476838

Centisome position: 24.31

GC content: 29.66

Gene sequence:

>789_bases
TTGTATTCTCATAGCCACAGTTATTTTAAGTGGTGTTTATTGGGTATTCGATGTTGTAAGGAGAGGAATAATGTGAGTGG
TAATATACTGATACTAGGCGCAGATGGATATATTGGTAAAGACTTACAAACAGTAATAGATGATACAAAAAATATATACT
GTATCGATAAAACGTATAAAGAAAAAGTAATGAAAGAAACCAATAAAGTCTATTTCAATTTAGATGTTAGCCAAGAAGAA
GATATTAGATTTTTATCCAATTACTTTGAAGAGAACAATATAACGATAGATGGTATTATCAACCTAATTGGGGTTAATAC
GTTATCTAATTTTTATAATGTGACAAATGAAGCGTGGGATAAAACATTTGATATAAACATTAAGAGTTTTGTATTTTTAC
TCAAGTCCATCTATAGTTCACTTTCACACCGCGTTTCAATTGTAAGTGTAGCTTCACAAAATGGTATAGTGGCACATGAG
GATAGAATTGCTTATGGTACTTCAAAAGCAGCGCTGATTCACTTAACAAAAAATTTAAGCATTGATTTTTTGAAGGATCA
ACAGAGAGATATTAAGGTGAATTGTGTGTCGCCATCCTATATTATCAACGATAATAACGAAAGTTATTTGAAGTCCTTTG
AAGGAAATAAGTTATTGAAAAAAATTCCATATAGAAAATTTGTTGAAATTTCAGATGTAACAAATATCATTTTATTTTTA
ATGTCTGATAAAAGCGATGCCATTAGAGGGCAAAATATTGTGGTTGACTATGGATATACAATTGTATAA

Upstream 100 bases:

>100_bases
ATCAAATGATAGGTTCAGAAGATTATATGAATAGTTTCAAACAATTTATATTCAAACGACAAAAGATAAAATCTTCTGAG
TTACTACTCGGACTAGTAAA

Downstream 100 bases:

>100_bases
ATAAATCATCTTGGGAATTAAGGGTGTGGATAATGAGTTTACTAATTAAAGATTTAACAAAGAAATTTGACGAGCATGTT
GCAGTGAATAATTTGAATAT

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MYSHSHSYFKWCLLGIRCCKERNNVSGNILILGADGYIGKDLQTVIDDTKNIYCIDKTYKEKVMKETNKVYFNLDVSQEE
DIRFLSNYFEENNITIDGIINLIGVNTLSNFYNVTNEAWDKTFDINIKSFVFLLKSIYSSLSHRVSIVSVASQNGIVAHE
DRIAYGTSKAALIHLTKNLSIDFLKDQQRDIKVNCVSPSYIINDNNESYLKSFEGNKLLKKIPYRKFVEISDVTNIILFL
MSDKSDAIRGQNIVVDYGYTIV

Sequences:

>Translated_262_residues
MYSHSHSYFKWCLLGIRCCKERNNVSGNILILGADGYIGKDLQTVIDDTKNIYCIDKTYKEKVMKETNKVYFNLDVSQEE
DIRFLSNYFEENNITIDGIINLIGVNTLSNFYNVTNEAWDKTFDINIKSFVFLLKSIYSSLSHRVSIVSVASQNGIVAHE
DRIAYGTSKAALIHLTKNLSIDFLKDQQRDIKVNCVSPSYIINDNNESYLKSFEGNKLLKKIPYRKFVEISDVTNIILFL
MSDKSDAIRGQNIVVDYGYTIV
>Mature_262_residues
MYSHSHSYFKWCLLGIRCCKERNNVSGNILILGADGYIGKDLQTVIDDTKNIYCIDKTYKEKVMKETNKVYFNLDVSQEE
DIRFLSNYFEENNITIDGIINLIGVNTLSNFYNVTNEAWDKTFDINIKSFVFLLKSIYSSLSHRVSIVSVASQNGIVAHE
DRIAYGTSKAALIHLTKNLSIDFLKDQQRDIKVNCVSPSYIINDNNESYLKSFEGNKLLKKIPYRKFVEISDVTNIILFL
MSDKSDAIRGQNIVVDYGYTIV

Specific function: Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=168, Percent_Identity=29.7619047619048, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI32483357, Length=187, Percent_Identity=29.9465240641711, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI5031737, Length=196, Percent_Identity=31.1224489795918, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=200, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=26.0700389105058, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=197, Percent_Identity=28.4263959390863, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=24.8, Blast_Score=77, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=25.609756097561, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=191, Percent_Identity=23.5602094240838, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=195, Percent_Identity=25.1282051282051, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=152, Percent_Identity=30.2631578947368, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=27.6150627615063, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355319, Length=193, Percent_Identity=32.6424870466321, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=24.2914979757085, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.163 [H]

Molecular weight: Translated: 30031; Mature: 30031

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSHSHSYFKWCLLGIRCCKERNNVSGNILILGADGYIGKDLQTVIDDTKNIYCIDKTYK
CCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCCCEEEECHHHH
EKVMKETNKVYFNLDVSQEEDIRFLSNYFEENNITIDGIINLIGVNTLSNFYNVTNEAWD
HHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC
KTFDINIKSFVFLLKSIYSSLSHRVSIVSVASQNGIVAHEDRIAYGTSKAALIHLTKNLS
EEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEECCCEEECCCCEEEEEEECCCE
IDFLKDQQRDIKVNCVSPSYIINDNNESYLKSFEGNKLLKKIPYRKFVEISDVTNIILFL
EEEECCCCCCEEEEEECCEEEEECCCHHHHHHCCCCHHHHHCCHHHEEEHHHHCEEEEEE
MSDKSDAIRGQNIVVDYGYTIV
ECCCCCCCCCCEEEEECCEEEC
>Mature Secondary Structure
MYSHSHSYFKWCLLGIRCCKERNNVSGNILILGADGYIGKDLQTVIDDTKNIYCIDKTYK
CCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCCCEEEECHHHH
EKVMKETNKVYFNLDVSQEEDIRFLSNYFEENNITIDGIINLIGVNTLSNFYNVTNEAWD
HHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC
KTFDINIKSFVFLLKSIYSSLSHRVSIVSVASQNGIVAHEDRIAYGTSKAALIHLTKNLS
EEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEECCCEEECCCCEEEEEEECCCE
IDFLKDQQRDIKVNCVSPSYIINDNNESYLKSFEGNKLLKKIPYRKFVEISDVTNIILFL
EEEECCCCCCEEEEEECCEEEEECCCHHHHHHCCCCHHHHHCCHHHEEEHHHHCEEEEEE
MSDKSDAIRGQNIVVDYGYTIV
ECCCCCCCCCCEEEEECCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12406764 [H]