| Definition | Bacillus thuringiensis str. Al Hakam chromosome, complete genome. |
|---|---|
| Accession | NC_008600 |
| Length | 5,257,091 |
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The map label for this gene is clpB [H]
Identifier: 118476751
GI number: 118476751
Start: 1181103
End: 1183703
Strand: Direct
Name: clpB [H]
Synonym: BALH_1032
Alternate gene names: 118476751
Gene position: 1181103-1183703 (Clockwise)
Preceding gene: 118476748
Following gene: 118476752
Centisome position: 22.47
GC content: 39.02
Gene sequence:
>2601_bases ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCACCATCA AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAAGATGGGCTAGCAGTACGTATTTTTCAAAAAATGA ATGTCGATATAGAAGCATTAAAACAAGGCGTAGAAAATTTAATTAAGAAAAAGCCTTCCGTAACGGGAAGCGGTGCAGAA GCAGGGAAATTATATATAACAGGTGCTCTGCAACAACTGCTTGTAAGAGCAGGAAAAGAAGCAGAGAAATTGCAAGATGA TTACATTTCAGTTGAACATGTATTGCTTGCTTTTACTGAAGAAAAAGGCGATATAAGCCAATTATTCACAAGATTTCATA TTACGAAAGACAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGCCAAAATCCAGAAGCAACT TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTGAAAGCAGGGAAAATTGACCCTGTTATCGGCCGCGA TAGTGAAATTCGCCGCGTAATCCGCATTCTTTCACGTAAAACGAAAAACAACCCTGTTTTAATTGGGGAACCAGGTGTTG GTAAAACAGCAATCGTTGAAGGGTTAGCACAGCGTATTGTGAAGAAGGATGTACCTGAAGGATTAAAAGATAGAACAATC TTTGCATTAGATATGAGTGCGCTTGTAGCTGGAGCGAAATTCCGCGGTGAGTTCGAAGAGCGTTTGCAAGCTGTATTAAA TGAAATTAAAAAGAGTGAAGGTCGCATTTTACTATTCATTGATGAACTTCACACAATCGTCGGCGCTGGAAAAACAGAAG GTGCGATGGATGCAGGGAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATCGGGGCGACAACACTAGAT GAATATCGTAAATATATTGAGAAAGATCCAGCACTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA AGATACAATTTCCATTTTACGTGGTTTAAAAGAGCGTTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCAATTG TAGCAGCATCAGTTTTATCAGATCGATATATTTCAGATCGTTTCTTACCGGATAAAGCAATTGATCTTGTTGACGAAGCG TGCGCAACAATTCGTACAGAAATTGATTCTATGCCGACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTAGAAAT TGAAGAAGCGGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGCCTCAAAACATTGCAACGTGAATTATCGGATT TAAAAGAAGTGGCAAGTAGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA CATTTAGAGCGTTTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAGAGCAGCGGAACTTCGCCACGG AAAAATTCCTGCAATTGAAAAAGAGTTAAAAGAAGCAGAAGAAATGGGCGCAAATAATAAACAAGAAAATCGTTTATTAC GTGAGGAAGTAAGTGAAGAAGAGATCGCTGAGATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT GAACGTGAGAAATTATTACGCTTAGAGCAAATTTTATCAGAACGTGTTATCGGACAAGAGGAAGCGGTAAGCCTAGTATC AGATGCAGTTCTTCGCGCGCGCGCTGGTATTAAAGATCCGAACCGTCCAATTGGTTCCTTCATCTTCTTAGGACCGACGG GGGTTGGTAAAACAGAGCTTGCCAAAACGTTAGCGCAGTCTTTATTTGATAGTGAAGAGCAAATGATTCGTATTGATATG TCTGAGTATATGGAGAAACACGCTGTGTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA ATTAACAGAAGCGGTAAGACGTAAACCGTATTCCGTTATTTTGTTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA ACATTTTATTACAAATGTTAGATGACGGTCGGATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACGGTTATT ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGAAGATGGCTCTATTAAAGAAGAATCAAGAGA ACTTGTAATGGGGCAATTAAGAGGGCATTTCCGACCAGAGTTTTTAAATCGCGTCGACGAAATTATTTTATTCAAACCTC TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCATATTACG GTACAATTAACAGACGCAGCAAAAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTACGGAGCTCGTCCATTAAAACG ATATGTACAGCGTCAAGTTGAAACGAAATTAGCGAGAGAATTAATTGCAGGTACGATTACTGACAATAGTCATGTAGTGG TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAAATAA
Upstream 100 bases:
>100_bases AGTTTGAAAATACATAAGCAAAATTATTGTATAAAAAAGTCAGTTAGCGTATAATCAAATCAAAGGTCAAAGAAAGTCAA ACATTTGGAGGACTGTAAAG
Downstream 100 bases:
>100_bases AAAAAGAGTTCGGATAAAATCCGGACTCTTTTTTTAGTGCTGTTCTACTGGCTCGTTTGGAATTGCAGCTGAAATTGCTA GTACTAATACCGCAAGAACA
Product: ATP-dependent Clp protease, ATP-binding subunit ClpB
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 866; Mature: 866
Protein sequence:
>866_residues MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVENLIKKKPSVTGSGAE AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT YEALEKYGRDLVAEVKAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEEEIAEIVSRWTGIPVAKLVEG EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT VQLTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK
Sequences:
>Translated_866_residues MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVENLIKKKPSVTGSGAE AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT YEALEKYGRDLVAEVKAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEEEIAEIVSRWTGIPVAKLVEG EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT VQLTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK >Mature_866_residues MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVENLIKKKPSVTGSGAE AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT YEALEKYGRDLVAEVKAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEEEIAEIVSRWTGIPVAKLVEG EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT VQLTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK
Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase
COG id: COG0542
COG function: function code O; ATPases with chaperone activity, ATP-binding subunit
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the clpA/clpB family [H]
Homologues:
Organism=Homo sapiens, GI13540606, Length=311, Percent_Identity=39.871382636656, Blast_Score=214, Evalue=2e-55, Organism=Escherichia coli, GI1788943, Length=862, Percent_Identity=54.1763341067285, Blast_Score=932, Evalue=0.0, Organism=Escherichia coli, GI1787109, Length=330, Percent_Identity=43.030303030303, Blast_Score=279, Evalue=5e-76, Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=51.8258426966292, Blast_Score=743, Evalue=0.0, Organism=Saccharomyces cerevisiae, GI6323002, Length=866, Percent_Identity=42.0323325635104, Blast_Score=676, Evalue=0.0,
Paralogues:
None
Copy number: 560 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR013093 - InterPro: IPR003959 - InterPro: IPR018368 - InterPro: IPR017730 - InterPro: IPR001270 - InterPro: IPR019489 - InterPro: IPR004176 - InterPro: IPR023150 [H]
Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]
EC number: NA
Molecular weight: Translated: 97546; Mature: 97546
Theoretical pI: Translated: 5.16; Mature: 5.16
Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEAL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHH KQGVENLIKKKPSVTGSGAEAGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTE HHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC EKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEATYEALEKYGRDLVAEVKAGKI CCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCC DPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI CCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGN EEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCHH MLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERF HHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH EIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEACATIRTEIDSMPTELDEVTR HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH RIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEE HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH EIAEIVSRWTGIPVAKLVEGEREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDP HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC NRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDMSEYMEKHAVSRLIGAPPGYV CCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCC GYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI CCCCCCHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECCEEE IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIK EEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHH GIVDKIVKELQGRLADRHITVQLTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARE HHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH LIAGTITDNSHVVVDVENNELVVHVK HHHHEECCCCEEEEEECCCEEEEEEC >Mature Secondary Structure MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEAL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHH KQGVENLIKKKPSVTGSGAEAGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTE HHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC EKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEATYEALEKYGRDLVAEVKAGKI CCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCC DPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI CCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGN EEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCHH MLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERF HHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH EIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEACATIRTEIDSMPTELDEVTR HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH RIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEE HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH EIAEIVSRWTGIPVAKLVEGEREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDP HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC NRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDMSEYMEKHAVSRLIGAPPGYV CCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCC GYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI CCCCCCHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECCEEE IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIK EEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHH GIVDKIVKELQGRLADRHITVQLTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARE HHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH LIAGTITDNSHVVVDVENNELVVHVK HHHHEECCCCEEEEEECCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12721629 [H]