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The map label for this gene is mrdB [H]

Identifier: 118476647

GI number: 118476647

Start: 1056415

End: 1057665

Strand: Direct

Name: mrdB [H]

Synonym: BALH_0923

Alternate gene names: 118476647

Gene position: 1056415-1057665 (Clockwise)

Preceding gene: 118476646

Following gene: 118476650

Centisome position: 20.1

GC content: 36.13

Gene sequence:

>1251_bases
TTGAATAAAAAAGGGGAGCATTTTTTACAAGAGGTTACGAACCATATTAAATCAAAAGAAGCGAAGGACTTGGTGGCAGC
GGAACTAGACTTTCACTTAAAACAGACGAAGAATAGGTGGGTGGATAAAGGATTAAGTGAGGAAGTTGCTGAAAATAAAG
CTGTGGAACAAATGGGAAGTCCGAGTAAGTTAGGGCAGGAGCTTAACAAACTGCATAAGCCAAAGGTGGATTGGTTTTTA
CTTATTTTGTTAGTGGCTGCGATGGGGCTAGGGTTTTTGCCAATAATCGCTCTTGGGCATACGAACGATTTACTAATGAA
CAAAATAATTTTTGTGACTCTTGGAATTGCCACAGCTATTGGGATGATGTTGCTTGATTACCGGAAGCTAGAAAGACTCG
GGTGGCTGTTTTATACAATTGGAATACTTATCTTGTTAGCTATAAAATGTTTTCCGACTGGTTACGTGATTGGGGAAGCA
ATAATAAAAATTGGCCCCATCAAAATTGATTGTTTAATGACGATACCATTCTTCTTTCTAGCTTGGACTTCTTTTTTCAA
TAATAGTAGGTTAAAGTTTATGCATCTTCTTATGTTGTACGTATTTTCTTTATATCTATTTTCAACTACAGCAATCCTTT
TACACATTTTCATCTATATTACGATGGTATTCGTTATGCTTTGGTGGAGTAAGCTAGGAAAGAAAACGGCATGGCTCATT
ACAATTTTACCTATTGTACCATTGATTATTAGGGATCTATTTTCCTGGTCTGCGGTAAAAGAATATCGGATAGCTAGAAT
TTTAGGATTTATAAACCCAGCGCATGATCAATGGGATTTACGTTTACAAGAGGCGATGTCTTCGGCAGGTTGGTTTGGTA
CATATGGAAATATAAAGTCTATCCCCGCTACCCATACTGATTTTGTATTTGCGAGTTTGACTTACTATTATGGATATGTG
CTTGCGTTAATTATTGTCTTCATTCTTTCTCTTTTTGCAGTAAGAATAATGAACATAGCTTATAAAATAAATGACGGTTA
TGGTAAATTGCTCCTCGTTGGCGGAGTGACTCTTTTTATAATCCATTGTATTTGTAACGTTGGCATGATCCTCGGGATAT
TACCACGTTTTTCTATATCATTACCTTTTATTAGTTATGGATTAGTACCAACTCTGTTTCATGCATTTATAATGGGAATC
GTACTAAGTGTATATCGACGTAAAGACATTCCAACGAGAAAATCAGCTTAA

Upstream 100 bases:

>100_bases
CAATTAAATGATAAAGGAAACAAGATGCTGCGAAAGGCAGAGAAGAATGCTACGAAGGCACGATTTATATTAAAAGGCTT
AGTACAGGAGTGAGAAAAAA

Downstream 100 bases:

>100_bases
AAAACAAACCACCTAGTCCCTATATTTTTTAGGGTGTAGGTGGTTTTATTTACACACTTAACAAGTTTTTCCGTTCTCAA
CTTCTCCGCATGAATCTGGA

Product: cell cycle protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNKKGEHFLQEVTNHIKSKEAKDLVAAELDFHLKQTKNRWVDKGLSEEVAENKAVEQMGSPSKLGQELNKLHKPKVDWFL
LILLVAAMGLGFLPIIALGHTNDLLMNKIIFVTLGIATAIGMMLLDYRKLERLGWLFYTIGILILLAIKCFPTGYVIGEA
IIKIGPIKIDCLMTIPFFFLAWTSFFNNSRLKFMHLLMLYVFSLYLFSTTAILLHIFIYITMVFVMLWWSKLGKKTAWLI
TILPIVPLIIRDLFSWSAVKEYRIARILGFINPAHDQWDLRLQEAMSSAGWFGTYGNIKSIPATHTDFVFASLTYYYGYV
LALIIVFILSLFAVRIMNIAYKINDGYGKLLLVGGVTLFIIHCICNVGMILGILPRFSISLPFISYGLVPTLFHAFIMGI
VLSVYRRKDIPTRKSA

Sequences:

>Translated_416_residues
MNKKGEHFLQEVTNHIKSKEAKDLVAAELDFHLKQTKNRWVDKGLSEEVAENKAVEQMGSPSKLGQELNKLHKPKVDWFL
LILLVAAMGLGFLPIIALGHTNDLLMNKIIFVTLGIATAIGMMLLDYRKLERLGWLFYTIGILILLAIKCFPTGYVIGEA
IIKIGPIKIDCLMTIPFFFLAWTSFFNNSRLKFMHLLMLYVFSLYLFSTTAILLHIFIYITMVFVMLWWSKLGKKTAWLI
TILPIVPLIIRDLFSWSAVKEYRIARILGFINPAHDQWDLRLQEAMSSAGWFGTYGNIKSIPATHTDFVFASLTYYYGYV
LALIIVFILSLFAVRIMNIAYKINDGYGKLLLVGGVTLFIIHCICNVGMILGILPRFSISLPFISYGLVPTLFHAFIMGI
VLSVYRRKDIPTRKSA
>Mature_416_residues
MNKKGEHFLQEVTNHIKSKEAKDLVAAELDFHLKQTKNRWVDKGLSEEVAENKAVEQMGSPSKLGQELNKLHKPKVDWFL
LILLVAAMGLGFLPIIALGHTNDLLMNKIIFVTLGIATAIGMMLLDYRKLERLGWLFYTIGILILLAIKCFPTGYVIGEA
IIKIGPIKIDCLMTIPFFFLAWTSFFNNSRLKFMHLLMLYVFSLYLFSTTAILLHIFIYITMVFVMLWWSKLGKKTAWLI
TILPIVPLIIRDLFSWSAVKEYRIARILGFINPAHDQWDLRLQEAMSSAGWFGTYGNIKSIPATHTDFVFASLTYYYGYV
LALIIVFILSLFAVRIMNIAYKINDGYGKLLLVGGVTLFIIHCICNVGMILGILPRFSISLPFISYGLVPTLFHAFIMGI
VLSVYRRKDIPTRKSA

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=167, Percent_Identity=31.7365269461078, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786853, Length=346, Percent_Identity=21.9653179190751, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47351; Mature: 47351

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]