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The map label for this gene is glpD [H]

Identifier: 118476643

GI number: 118476643

Start: 1051598

End: 1053319

Strand: Direct

Name: glpD [H]

Synonym: BALH_0919

Alternate gene names: 118476643

Gene position: 1051598-1053319 (Clockwise)

Preceding gene: 118476642

Following gene: 118476644

Centisome position: 20.0

GC content: 40.77

Gene sequence:

>1722_bases
TTGTGGTCTCTTTTTTCGTTATCAAAGGGAGGAATTACCATGAAATTTTCAAGTAAACAACGTAAAGACGTATTAAACGG
AGTAAATAAACAAGAATTAGATGTGATCGTAATTGGTGGAGGTATTACTGGTTCTGGTATTGCATTAGATGGAGCAACAC
GCGGGTTATCAACAATTGTGTTTGAAATGCAGGACTTTGCAGCAGGTACATCAAGTCGTTCAACGAAGCTTGTACACGGT
GGTCTACGTTATTTAAAACAACTTGAAGTGAAAATGGTAGCAGAGGTGGGTAAAGAGCGTGCGATCGTATATGAGAACGG
TCCCCATGTAACAACACCAGAGTGGATGTTACTTCCGTTCCATACAGGAGGTACGTTCGGATCATTTAGTACATCAATTG
GTCTTCGTGTATACGACTTCTTAGCAGGTGTAAAACGAAGTGAGCGCAGAAAAATGTTTAACCGTGAAGAAACGCTGAAG
AAAGAGCCTCTTGTAAAACAAGAAGGATTAAAAGGCGGCGGTTACTACGTAGAATATCGTACAGACGATGCGCGTCTTAC
AATTGAAGTAATGAAAGAAGCAATTGAGCACGGCGCAAAAGCTGTTAACTACGCAAAAGTAGACGGTTTCTTATATAAAG
ATGGAAAAGTATGTGGTGTACGTGTAATCGATTTACTAGACGGAGAAGTATACGAAGTTTACGGTAAGAAAATTGTAAAC
GCAGCTGGCCCTTGGGTAGATACACTTCGTGAAAAAGATAACTCGAAAAAAGGAAAAGTACTTCAGTTATCAAAAGGTGT
TCACTTAGTAATTGATCAAAAACGTTTCCCATTAGGTCAAGCGATTTACTTCGATACACCAGATAAACGTATGGTATTCG
CGATTCCGCGCGGCGGAAAAACATACGTAGGTACAACAGATACGTTCTATGATAAAGACGCAGCTGTACCACAAATGACA
ACAGAAGATCGCACATACATCATTAATGCGATTAACTACATGTTCCCAAGCGTAAAAATTACGGAAAAAGACATCGAATC
AAGCTGGGCTGGTGTACGTCCGTTAATTTACGAAGAAGGTAAGAGTGCATCTGAAATTTCTCGTAAAGACGAAATTTGGA
CTTCTGAATCTGGTTTAATTACAATCGCTGGTGGTAAATTAACAGGATACCGCAAAATGGCTGAAATGGTAGTAGACTAC
GTAACGAACTTACTACAAAAAGAAGGTCATAGTGCATATCCGAAGAGCTCAACGAAACATATGCCAATCTCTGGTGGACA
TGTAGATGGCTCTAAAGGATTACCAGCATTTATCGCGAAAAAAGCAGGCGAAGGTACGAAATACGGTTTAACGACAGCAC
AAGCAGAAGAATTCGCGAAATTCTACGGCTCTAACGTTGACGTACTATTTGACCTAGCGAAAAAACATAAAGACGAAGCA
AAAGAATATAACATGCCGCTAGACGTTCTAATCCCACTTGTATACGCAATGGATTACGAAATGACAGCAAAACCAGTCGA
CTTCTTCGTACGCCGCAGAGGCGCTGTATTCTTCAACATCCACTGGGTATATGAGTGGAAAGAAGCAGTAATCAACTACA
TGGCTGCGAAACTAGGCTGGAGCAAAGAAGAGCAAATGAAATACACAGCAGAACTAGAAAAAGCATTAAGAGACGCTGTC
ATTCCTGTAGATCAACAAGAGCAGGCAGCTGCGTTAGCGTAA

Upstream 100 bases:

>100_bases
AAATAATCATAAACAGTGTTATAATGGTGACAAGTTAATAATTCGGTAGGAGATTTGGAGAGACCACAACACGCTATAGA
GGCGAAATCTATAGCGGAGT

Downstream 100 bases:

>100_bases
AATGAGAAACACCTGAAGGCGAGCCCTTTAGGTGTTTTTTCTCTTGACTAAAAATAATTAGAATGTGTTACAATGATGAT
AGAGTATGTAGTATGAATTT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MWSLFSLSKGGITMKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHG
GLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLK
KEPLVKQEGLKGGGYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVN
AAGPWVDTLREKDNSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMT
TEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDY
VTNLLQKEGHSAYPKSSTKHMPISGGHVDGSKGLPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEA
KEYNMPLDVLIPLVYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALRDAV
IPVDQQEQAAALA

Sequences:

>Translated_573_residues
MWSLFSLSKGGITMKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHG
GLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLK
KEPLVKQEGLKGGGYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVN
AAGPWVDTLREKDNSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMT
TEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDY
VTNLLQKEGHSAYPKSSTKHMPISGGHVDGSKGLPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEA
KEYNMPLDVLIPLVYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALRDAV
IPVDQQEQAAALA
>Mature_573_residues
MWSLFSLSKGGITMKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHG
GLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLK
KEPLVKQEGLKGGGYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVN
AAGPWVDTLREKDNSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMT
TEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDY
VTNLLQKEGHSAYPKSSTKHMPISGGHVDGSKGLPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEA
KEYNMPLDVLIPLVYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALRDAV
IPVDQQEQAAALA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=548, Percent_Identity=32.8467153284672, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI285002231, Length=548, Percent_Identity=32.8467153284672, Blast_Score=260, Evalue=2e-69,
Organism=Escherichia coli, GI2367226, Length=470, Percent_Identity=29.5744680851064, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788574, Length=371, Percent_Identity=26.9541778975741, Blast_Score=92, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17509253, Length=558, Percent_Identity=33.1541218637993, Blast_Score=251, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI115534726, Length=548, Percent_Identity=33.029197080292, Blast_Score=221, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6322036, Length=610, Percent_Identity=29.016393442623, Blast_Score=215, Evalue=1e-56,
Organism=Drosophila melanogaster, GI161077125, Length=566, Percent_Identity=33.3922261484099, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24653942, Length=566, Percent_Identity=33.3922261484099, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24653944, Length=566, Percent_Identity=33.3922261484099, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI20130025, Length=566, Percent_Identity=33.3922261484099, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24586295, Length=558, Percent_Identity=28.494623655914, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI19921278, Length=550, Percent_Identity=26.5454545454545, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI45550977, Length=401, Percent_Identity=24.1895261845387, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 63898; Mature: 63898

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSLFSLSKGGITMKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIV
CCCCEEECCCCEEEEECCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHH
FEMQDFAAGTSSRSTKLVHGGLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPF
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEE
HTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLKKEPLVKQEGLKGGGYYVEYR
ECCCCCCCCHHHCCHHHHHHHHHCHHHHHHHHHCHHHHHHHCCCHHHCCCCCCCEEEEEE
TDDARLTIEVMKEAIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVN
CCCCEEEHHHHHHHHHHCHHHCEEEEECCEEEECCCEEEEEEEEHHCCHHHHHHHHHHHH
AAGPWVDTLREKDNSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGK
CCCCHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCC
TYVGTTDTFYDKDAAVPQMTTEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEG
EEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCEEEHHHHHHCCCCCCCEEEECC
KSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAYPKSSTKH
CCHHHHHHHHCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
MPISGGHVDGSKGLPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEA
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KEYNMPLDVLIPLVYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGW
HHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEEEEEHHHHHHHHHHHHCCC
SKEEQMKYTAELEKALRDAVIPVDQQEQAAALA
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure
MWSLFSLSKGGITMKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIV
CCCCEEECCCCEEEEECCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHH
FEMQDFAAGTSSRSTKLVHGGLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPF
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEE
HTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLKKEPLVKQEGLKGGGYYVEYR
ECCCCCCCCHHHCCHHHHHHHHHCHHHHHHHHHCHHHHHHHCCCHHHCCCCCCCEEEEEE
TDDARLTIEVMKEAIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVN
CCCCEEEHHHHHHHHHHCHHHCEEEEECCEEEECCCEEEEEEEEHHCCHHHHHHHHHHHH
AAGPWVDTLREKDNSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGK
CCCCHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCC
TYVGTTDTFYDKDAAVPQMTTEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEG
EEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCEEEHHHHHHCCCCCCCEEEECC
KSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAYPKSSTKH
CCHHHHHHHHCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
MPISGGHVDGSKGLPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEA
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KEYNMPLDVLIPLVYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGW
HHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEEEEEHHHHHHHHHHHHCCC
SKEEQMKYTAELEKALRDAVIPVDQQEQAAALA
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]