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The map label for this gene is rsbW [H]

Identifier: 118476613

GI number: 118476613

Start: 1017946

End: 1018428

Strand: Direct

Name: rsbW [H]

Synonym: BALH_0888

Alternate gene names: 118476613

Gene position: 1017946-1018428 (Clockwise)

Preceding gene: 118476612

Following gene: 118476614

Centisome position: 19.36

GC content: 33.13

Gene sequence:

>483_bases
ATGATGGAGAGATTTGAAAAGATAGAAATGAAAATTCCTGCAAAGGCAGAATATGTGGCTATTATTCGTTTAACAATGGC
TGGTGTTGCAAATCGAATGGGCTTTGCTTATGACGATATAGAAGATATGAAAATTGCTATTAGTGAAGCATGTACAAATA
TTGTACAACATGCATACAAAGAAGACGTTGGAGAAATTGCAATTGTCTTTGGGCTATATGAAAATCGATTAGAAATTATG
GTTGCTGATAATGGGGTTAGCTTTGATTTTAATAACTTAAAAAGGAAAGTTGGTCCGTATGATATTAGTAAACCTGTAGA
ACATTTGCCTGAAAATGGTTTAGGTTTATATTTAATCAATACGTTAATGGATGATATACAAATCATGCATGATGAGGGCA
TGACGGTTTTAATGACAAAATATATACAAAGAGAGCAGGTGGAGAATGATGGAAATCCAATCTCAACCTACGAATCTTAC
TAA

Upstream 100 bases:

>100_bases
TGTATCTAAAAGGTTAAAAAGATTATTTGATATTACAGGGTTAACAGAAATATTAAATTTGAATTCCGATTTTGAAAAAG
TAGAAAGAAGGTGACTAGGG

Downstream 100 bases:

>100_bases
AGAAGACGTTATTAAACTAATTGCAGAATTTCAACAAAACCAATGTGGTGAAGCGCAGGAAAGGTTAGTTGATCATTATA
AAAATCTCGTATATTCCATT

Product: serine-protein kinase RsbW

Products: NA

Alternate protein names: Anti-sigma-B factor; Sigma-B negative effector rsbW [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYKEDVGEIAIVFGLYENRLEIM
VADNGVSFDFNNLKRKVGPYDISKPVEHLPENGLGLYLINTLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY

Sequences:

>Translated_160_residues
MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYKEDVGEIAIVFGLYENRLEIM
VADNGVSFDFNNLKRKVGPYDISKPVEHLPENGLGLYLINTLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY
>Mature_160_residues
MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYKEDVGEIAIVFGLYENRLEIM
VADNGVSFDFNNLKRKVGPYDISKPVEHLPENGLGLYLINTLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY

Specific function: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, rsbV. Upon phosphorylation of rsbV, rsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010193
- InterPro:   IPR003594 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 18282; Mature: 18282

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYK
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EDVGEIAIVFGLYENRLEIMVADNGVSFDFNNLKRKVGPYDISKPVEHLPENGLGLYLIN
HCHHHEEEEEEEECCCEEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHH
TLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYK
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EDVGEIAIVFGLYENRLEIMVADNGVSFDFNNLKRKVGPYDISKPVEHLPENGLGLYLIN
HCHHHEEEEEEEECCCEEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHH
TLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA