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The map label for this gene is dhaK [H]

Identifier: 118476597

GI number: 118476597

Start: 1000714

End: 1002465

Strand: Direct

Name: dhaK [H]

Synonym: BALH_0872

Alternate gene names: 118476597

Gene position: 1000714-1002465 (Clockwise)

Preceding gene: 118476594

Following gene: 118476599

Centisome position: 19.04

GC content: 42.24

Gene sequence:

>1752_bases
ATGAAAAAGATTATAAACAAACCAGAAACATTAGTAATGGAAATGTGCAACGGAATGGTTATGGCTCATCCAGAGCTTGA
GCTTTTGAAAAAATATAAAGTCATCAAGAAGAAAGAAATGAACGAAAACAAAGTAACGTTAATTAGTGGCGGCGGTAGTG
GTCACGAGCCAGCGCATGCAGGACTAGTCGGAAAAGGAATGTTAGATGCGGCAGTGTGCGGAGATGTGTTTGCTTCGCCT
TCACAAATTCAGGTATATCAAGCGATTAAAGAGACAGCTAGTAAAAAAGGTACGCTATTAATTATTAAAAATTACAGCGG
CGATATTATGAATTTCAAAAACGGTGCTCATTTAGCGACGGAAGATGGAATTGAAGTCGACTACGTAAAAGTGGACGATG
ATATTGCGGTAGAAGATAGCCTGTACACAGTAGGACGCCGCGGCGTTGCGGGTGTTATTCTCGTTCATAAAATTGCCGGC
GCAGCAGCGGAAGCAGGTATGGATTTAGGAGCGGTGAAAGCTGTAGCGGAAAAAGCAGCTGCTAACGTGCGTACAATTGG
TTTAGCGTTAACGTCTTGTACAGTTCCAGCGAGCGGATCACCTACTTTCACACTTGCGGAAGATGAAATGGAATACGGCG
TAGGTATTCACGGCGAACCAGGAATTAAACGTGAAAAAATGCTGTCAGCAGATGAATTAGCGAACCGTATGACAAACGAT
TTAATGAAAGATTTAGGAGTAAAAGACGGAGAAGAAATTGCGCTTTTAGTTAACGGTTTTGGCGGAACACCACTGCAAGA
ACTTTACTTATTTAACAACGCAGTGACGCGAGAATTAGCTGCTAGAAATATTAAAATTAATAGAGTATTCGTCGGCAATT
ATATGACGAGTATCGATATGGCTGGTATGTCTTTAACAGTGATGAAATTAGATGATGAGTTAAAAACATTATTATCGAAA
GAGTGTAATACACCAGCGTTTAAAGTAGATGGGCCAGTTGAAAGTGTAGAGTACGTAAATGTGCTTGAAGAGACAGAAGA
GAAGGAAGTTTCCTTTGAAATAGAAACGGCGGAAGAGCACGCAGTTATTAAAAATAATGTCATCACATTAAACAACATGA
TTTATCTCGTTGATAAAATGAGCGATATTATTATTAAAAATGAAGTACCGTTCTGTGAGTTAGATACACATGCAGGTGAT
GGCGATTTCGGAATGAGTGTGGCAAAAGGATTTAAGCAATTAAAACGTGAATGGCATTCGATTGTAGAACAAGAAAACGT
AACAATCGGATCATTCCTTGACGGTTGTTCGATGATTATTATGGAACATTGCGGCGGCGCATCTGGCCCAATTTGGGGCG
GAGCATTCCGCGCAGCTAGTAAAGCAGCCGGCGAGAAGCGTGAGCTAACAGTGAAAGAATTCGCTGAAATGTTGCAAGCA
GCACTGCAAGGCATACAATCGATCGGTGAAAGATCATTCGGCAGAGGAGCGGTAGTTGGAGACAAAACACTTGTTGACGC
CCTTGCTCCATGTGTAGACTCTTGGTTAGCTAGCGCTTCAAACGAAGAAGACATGAAAACTGCCTTTGAAAAAGGAGCAG
AAGCAGCGGTTAAAGGAGCAGAGTACACGAAAGAAATCGTAGCTCGCATGGGCCGCGCTGGTACAGTTGGCGAAAGAAGT
TTAGGATATCCAGATGCAGGTGCACATGCGCTTGGGGTTATCTTTACGGAGATTGCGGGTAGTTTGAAATAG

Upstream 100 bases:

>100_bases
TTTGTCCGTTTACTATAAAACGCTTTCATTTTAACATGGATAGTAAGAAGAAGATTTCAAATATATCACAATATATTAAA
GGAATTGAGGGAGAATCACA

Downstream 100 bases:

>100_bases
GAATTGGAAAGTCCCCTCTGCCTTAAGGTGGAGGGGATCTTTATTTATAACCATCATTCTTCCAGTGAAAAAATTTATTT
GTTAGCCAATCTAGAAGCAG

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFEIETAEEHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK

Sequences:

>Translated_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFEIETAEEHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK
>Mature_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFEIETAEEHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=576, Percent_Identity=32.9861111111111, Blast_Score=283, Evalue=2e-76,
Organism=Escherichia coli, GI87081857, Length=353, Percent_Identity=40.7932011331445, Blast_Score=277, Evalue=2e-75,
Organism=Escherichia coli, GI1787449, Length=212, Percent_Identity=28.7735849056604, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17565018, Length=581, Percent_Identity=31.3253012048193, Blast_Score=270, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6321055, Length=601, Percent_Identity=31.9467554076539, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6323570, Length=583, Percent_Identity=32.0754716981132, Blast_Score=210, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 62475; Mature: 62475

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCEEC
EDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEAGMDLGAVKAVAEKAA
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
CCHHEEEEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHH
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDM
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHH
AGMSLTVMKLDDELKTLLSKECNTPAFKVDGPVESVEYVNVLEETEEKEVSFEIETAEEH
CCCEEEEEECCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCC
AVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGDGDFGMSVAKGFKQLKREWHS
HHHHCCEEEECCEEEEEEHHHHEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
IVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
EYTKEIVARMGRAGTVGERSLGYPDAGAHALGVIFTEIAGSLK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCEEC
EDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEAGMDLGAVKAVAEKAA
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
CCHHEEEEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHH
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDM
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHH
AGMSLTVMKLDDELKTLLSKECNTPAFKVDGPVESVEYVNVLEETEEKEVSFEIETAEEH
CCCEEEEEECCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCC
AVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGDGDFGMSVAKGFKQLKREWHS
HHHHCCEEEECCEEEEEEHHHHEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
IVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
EYTKEIVARMGRAGTVGERSLGYPDAGAHALGVIFTEIAGSLK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]