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The map label for this gene is tcyB [H]

Identifier: 118476507

GI number: 118476507

Start: 886832

End: 887536

Strand: Direct

Name: tcyB [H]

Synonym: BALH_0775

Alternate gene names: 118476507

Gene position: 886832-887536 (Clockwise)

Preceding gene: 118476506

Following gene: 118476508

Centisome position: 16.87

GC content: 36.74

Gene sequence:

>705_bases
GTGAAAATGTATCTAAGTAGTGCATTGGCTTCAGATCGATTGTCTACTTGGATAGATATTATGCAGTCTTCCTTCATGCC
TATGCTGAAGGAAGCTGTTTTTACGACAATTCCATTAACGCTTATTACATTTATTATCGGGATTATACTTGCGACGTTAA
CGGCGCTTGCACGTATTTCAGGTAGTCGTATTTTACAATGGATTGCTCGTATCTATGTATCTATCATTCGCGGAACGCCA
CTTCTTGTACAGTTATTTATTATTTTCTATGGTCTTCCAACTCTTAATGTTGAAGTTGAGCCATATACAGCAGCAGTAAT
TGGATTTTCATTAAATGTCGGTGCATATGCATCTGAAATTATTCGTGCTTCTATCCTTTCGATTCCGAAAGGGCAGTGGG
AAGCAGCTTATACAATTGGGATGACATACCCACAAGCGTTAAAACGTGTTATTTTACCGCAAGCAACGCGTGTATCAATC
CCGCCGCTTTCGAATACATTTATTAGCTTAGTGAAAGATACTTCATTAGCATCGTTAATTTTAGTAACAGAAATGTTCCG
AAAAGCGCAGGAAATTGCGGCAATGAACTATGAGTTTTTAATTGTTTATTTTGAAGCAGGTCTTATTTATTGGGTTATTT
GTTTCTTATTATCAATCGTACAACAGATGTTAGAAAAGCGTTCAGAACGCTACACATTAAAATAA

Upstream 100 bases:

>100_bases
TTCCGTAAAGGTAGCGACAAGCTAGTACAAGAAGTAGATAAAGCGTTAGAAGATATGAAAAAAGATGGTACGTACGATAA
AATAGCGAAAAAATGGTTCG

Downstream 100 bases:

>100_bases
TCCTTTTACAAAAGGAGTTTTTGTTTTTATGATTTCAATTCAGCACTTACAAAAAAGTTTCGGAGATAATACCGTACTAA
AGCATATAGATTTAACAGTT

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKMYLSSALASDRLSTWIDIMQSSFMPMLKEAVFTTIPLTLITFIIGIILATLTALARISGSRILQWIARIYVSIIRGTP
LLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSI
PPLSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK

Sequences:

>Translated_234_residues
MKMYLSSALASDRLSTWIDIMQSSFMPMLKEAVFTTIPLTLITFIIGIILATLTALARISGSRILQWIARIYVSIIRGTP
LLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSI
PPLSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK
>Mature_234_residues
MKMYLSSALASDRLSTWIDIMQSSFMPMLKEAVFTTIPLTLITFIIGIILATLTALARISGSRILQWIARIYVSIIRGTP
LLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSI
PPLSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=205, Percent_Identity=49.7560975609756, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=36.2745098039216, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=32.2429906542056, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786873, Length=220, Percent_Identity=34.0909090909091, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787087, Length=233, Percent_Identity=28.755364806867, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082239, Length=200, Percent_Identity=37.5, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788645, Length=226, Percent_Identity=29.646017699115, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788646, Length=218, Percent_Identity=27.5229357798165, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786874, Length=170, Percent_Identity=31.1764705882353, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI48994930, Length=122, Percent_Identity=38.5245901639344, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26308; Mature: 26308

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMYLSSALASDRLSTWIDIMQSSFMPMLKEAVFTTIPLTLITFIIGIILATLTALARIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSRILQWIARIYVSIIRGTPLLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASEI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCHHEEEEEEECCCHHHHHHH
IRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSIPPLSNTFISLVKDTSLASLI
HHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHH
LVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK
HHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKMYLSSALASDRLSTWIDIMQSSFMPMLKEAVFTTIPLTLITFIIGIILATLTALARIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSRILQWIARIYVSIIRGTPLLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASEI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCHHEEEEEEECCCHHHHHHH
IRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSIPPLSNTFISLVKDTSLASLI
HHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHH
LVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK
HHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]