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The map label for this gene is ywoG [H]

Identifier: 118476357

GI number: 118476357

Start: 712263

End: 713441

Strand: Reverse

Name: ywoG [H]

Synonym: BALH_0615

Alternate gene names: 118476357

Gene position: 713441-712263 (Counterclockwise)

Preceding gene: 118476363

Following gene: 118476346

Centisome position: 13.57

GC content: 36.56

Gene sequence:

>1179_bases
TTGAAATATTTTATTTACTTTATTGTTATCGTAGCGTTTCTAGATACATTTTCACAATTACCTATTATGAGTACGTTCGC
TCAAAGTCTTGGAGGATCCCCTCTTATTATTGGGCTAGTTGTCGGCATGTACTCATTCGCTAATATGATCGGTAATATTA
TTGCTGGCGCTGCTGTCGATAAATTTGGTGCAAAAAAAATACTTTATATAAGCATGGGACTTACGAGTTTCATAGTCTTG
TTATACACTGTTGTTCAAAGTGGTGAACAACTATTAGTTGTGCGCTTTATGCATGGCTTTAGTGACGGATTTTTAATTCC
CGCTGCCTTTACGTTTTTATCAAAACAAACAAATGCAGCAAGACAAGGTAAGGCAATGGCTCTATCTGGTGCTGCTGTTG
GAACAGCGGCAATTGTAGGACCTGCTTTTAGCGGTATTATGAAAGCAACTGCTGGTATAGAGTGGGTGTTCATTACCATT
TCTATTTTAATGGTTCTTGGTACAATCGTATCTCTATTCTTCTTACCAAATAACGTATCAAGAAAAGATACTTCAAGAAC
ACAAATGATGAACAAAGAAGATATGTTTGAACTATTGAAATCAGAACCGTTATTACAGGCGTATATTGGTGCTTTCACAC
TCATGTTTTCACAAGGAATTGTCACTTACATGTTACCAGTGAAAGTTGAGGCATTGGCACTTAAAGCATCTACAACAGGC
ATGATGTTAAGTGTATTCGGCATTACCGCTATCCTCTTCTTCTTACTACCAACAAATCGTATTTATGATCGATTTAATCG
TTCAAAACTAATGCTAATCGGTATTGCAGTAATGGCATTAGCATTATCTTTACTTGGATTATTCGCAACAAAAGGCATGC
TCTTTATCGTTATGATGATTTATGGCATTGGATTCGCTATCCTTTTCCCATCGATAAATGCATTACTTGTTGAAAATACG
ACAGATGATAAACGTGGAAAAGCATTCGGATTGTTTTATGCTTTCTTCTCATTAGGAGTTGTTGCTGGATCCTTTACAGT
TGGAGCAATCGGGGCATCCCCTAGCGTCAGCTTCGTTATTGGAACTGCATTCTTATTAACATTCGCTGGAATGATTTATG
TAAGAAGCAAAGTAAAAAGTAAAGCAAAAAGCAAAGTAAAAAAGACAATGATGGGATAA

Upstream 100 bases:

>100_bases
TATTTTGTCACTTTGTACTTTTTTCCACATCTGTTAATTCAATTTCATTGCGGTTGAAATTCGCATTATGCCATAATAGC
ATAGGAGAGGTGAATATCGC

Downstream 100 bases:

>100_bases
CTCCATCATTGTCTTTTTTTCGCCTAATATATATTACTTTTGCATATAACCAAGTAATACTGTAAATAAACTTATGTATA
AAGACAATACTACATTTCTT

Product: multidrug efflux transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVDKFGAKKILYISMGLTSFIVL
LYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAARQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITI
SILMVLGTIVSLFFLPNNVSRKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
MMLSVFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMIYGIGFAILFPSINALLVENT
TDDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVIGTAFLLTFAGMIYVRSKVKSKAKSKVKKTMMG

Sequences:

>Translated_392_residues
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVDKFGAKKILYISMGLTSFIVL
LYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAARQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITI
SILMVLGTIVSLFFLPNNVSRKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
MMLSVFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMIYGIGFAILFPSINALLVENT
TDDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVIGTAFLLTFAGMIYVRSKVKSKAKSKVKKTMMG
>Mature_392_residues
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVDKFGAKKILYISMGLTSFIVL
LYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAARQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITI
SILMVLGTIVSLFFLPNNVSRKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
MMLSVFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMIYGIGFAILFPSINALLVENT
TDDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVIGTAFLLTFAGMIYVRSKVKSKAKSKVKKTMMG

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42278; Mature: 42278

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS00018 EF_HAND_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVD
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFGAKKILYISMGLTSFIVLLYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAA
HCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCCHHHHHHHHHHHHCCHH
RQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITISILMVLGTIVSLFFLPNNVS
HCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
RKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
CCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHEEEHHHEEEHHEEECCCCH
MMLSVFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMI
HHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGIGFAILFPSINALLVENTTDDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVI
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
GTAFLLTFAGMIYVRSKVKSKAKSKVKKTMMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVD
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFGAKKILYISMGLTSFIVLLYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAA
HCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCCHHHHHHHHHHHHCCHH
RQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITISILMVLGTIVSLFFLPNNVS
HCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
RKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
CCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHEEEHHHEEEHHEEECCCCH
MMLSVFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMI
HHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGIGFAILFPSINALLVENTTDDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVI
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
GTAFLLTFAGMIYVRSKVKSKAKSKVKKTMMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]